Results 1 to 10 of about 848,055 (251)
Interleukin-22 From Type 3 Innate Lymphoid Cells Aggravates Lupus Nephritis by Promoting Macrophage Infiltration in Lupus-Prone Mice [PDF]
Frontiers in Immunology, 2021 Lupus nephritis (LN) is one of the most severe manifestations of systemic lupus erythematosus (SLE). Our previous studies demonstrated increased serum and renal Interleukin (IL)-22 in LN patients and MRL/lpr mice.
Lingzhen Hu +6 more
doaj +2 more sources
Interleukin-22 and acute pancreatitis: A review. [PDF]
Medicine (Baltimore), 2023 Acute pancreatitis (AP) is one of the most common gastrointestinal diseases, and it is divided into 3 types according to its severity:mild acute pancreatitis, moderately severe acute pancreatitis, and severe acute pancreatitis. The mortality in severe acute pancreatitis is approximately 15% to 30% due to multiorgan dysfunction and the lack of specific ...
Fu X, Xiu Z, Xu H.
europepmc +3 more sources
Protective function of interleukin‐22 in pulmonary fibrosis [PDF]
Clinical and Translational Medicine, 2021 Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive scarring disease with unknown etiology. The evidence of a pathogenic role for transforming growth factor‐beta (TGF‐β) in the development and progression of IPF is overwhelming.
Peiyu Gu +12 more
doaj +2 more sources
Interleukin-22: Immunobiology and Pathology [PDF]
Annual Review of Immunology, 2015 Interleukin-22 (IL-22) is a recently described IL-10 family cytokine that is produced by T helper (Th) 17 cells, γδ T cells, NKT cells, and newly described innate lymphoid cells (ILCs). Knowledge of IL-22 biology has evolved rapidly since its discovery in 2000, and a role for IL-22 has been identified in numerous tissues, including the intestines, lung,
Jarrod A Dudakov +2 more
exaly +3 more sources
Targeting interleukin-22 for cancer therapy [PDF]
Human Vaccines & Immunotherapeutics, 2018 Interleukin-22 (IL-22) is a member of IL-10 family of cytokines. IL-22 induces proliferative and anti-apoptotic signaling pathways and production of anti-microbial molecules that enhance tissue regeneration and host defense.
Anamarija Markota +2 more
doaj +3 more sources
Interleukin 22 and its association with neurodegenerative disease activity [PDF]
Frontiers in Pharmacology, 2022 It is worth noting that neuroinflammation is well recognized as a symptom of neurodegenerative diseases (NDs). The regulation of neuroinflammation becomes an attractive focus for innovative ND treatment technologies.
Wenjian Chen +8 more
doaj +2 more sources
Interleukin-22 Inhibits Bleomycin-Induced Pulmonary Fibrosis [PDF]
Mediators of Inflammation, 2013 Pulmonary fibrosis is a progressive and fatal fibrotic disease of the lungs with unclear etiology. Recent insight has suggested that early injury/inflammation of alveolar epithelial cells could lead to dysregulation of tissue repair driven by multiple ...
Minrui Liang +11 more
doaj +4 more sources
Plasma interleukin-22 concentration and disease activity in inflammatory bowel disease [PDF]
Scientific ReportsThe relationship between interleukin-22 and clinical characteristics of patients with inflammatory bowel disease is uncertain. We sought to determine whether plasma interleukin-22 concentrations are associated with disease activity in a large population ...
Claudia Cabrera +10 more
doaj +2 more sources
Interleukin-22: a potential therapeutic target in atherosclerosis [PDF]
Molecular Medicine, 2021 Background Atherosclerosis is recognized as a chronic immuno-inflammatory disease that is characterized by the accumulation of immune cells and lipids in the vascular wall.
Jin-Wen Luo +4 more
doaj +2 more sources
Interleukin-22 mitigates acute respiratory distress syndrome (ARDS). [PDF]
PLoS ONE, 2021 BackgroundThe goal of this study was to determine if IL-22:Fc would Acute Respiratory Distress Syndrome (ARDS).Summary background dataNo therapies exist for ARDS and treatment is purely supportive.
Sharven Taghavi +9 more
doaj +2 more sources