Results 1 to 10 of about 60,800,054 (257)

Plasma interleukin-22 concentration and disease activity in inflammatory bowel disease [PDF]

Scientific Reports
The relationship between interleukin-22 and clinical characteristics of patients with inflammatory bowel disease is uncertain. We sought to determine whether plasma interleukin-22 concentrations are associated with disease activity in a large population ...
Claudia Cabrera, Daniel Fernández-Llaneza, Marita Olsson, Charles Sopp, Tara Fehlmann, Elizabeth A. Duncan, Emon Khan, Junmei Cairns, Jessica Neisen, Ulf Gehrmann, Nick Powell   +10 more
doaj   +3 more sources

Protective function of interleukin‐22 in pulmonary fibrosis [PDF]

Clinical and Translational Medicine, 2021
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive scarring disease with unknown etiology. The evidence of a pathogenic role for transforming growth factor‐beta (TGF‐β) in the development and progression of IPF is overwhelming.
Peiyu Gu, Dandan Wang, Ji Zhang, Xin Wang, Zhiyong Chen, Lina Gu, Mengying Liu, Fanqing Meng, Jun Yang, Hourong Cai, Yonglong Xiao, Yin Chen, Mengshu Cao   +12 more
doaj   +2 more sources

Interleukin 22 and its association with neurodegenerative disease activity [PDF]

Frontiers in Pharmacology, 2022
It is worth noting that neuroinflammation is well recognized as a symptom of neurodegenerative diseases (NDs). The regulation of neuroinflammation becomes an attractive focus for innovative ND treatment technologies.
Wenjian Chen, Jianpeng Wang, Huaizhi Yang, Yuankai Sun, Bangjie Chen, Yuchen Liu, Yanxun Han, Ming Shan, Junfeng Zhan   +8 more
doaj   +2 more sources

Interleukin 18 and interleukin 22 as important immune markers in patients with tuberculosis [PDF]

E3S Web of Conferences, 2023
Tuberculosis (TB) is a lung infection caused by the bacterium Mycobacterium tuberculosis (MTB). TB is a leading cause of death globally, accounting for approximately 1.5 million deaths per year.
Kamoona Firas Mohammad Hussein, Aljanaby Ahmed Abduljabbar Jaloob   +1 more
doaj   +1 more source

Interleukin-22 From Type 3 Innate Lymphoid Cells Aggravates Lupus Nephritis by Promoting Macrophage Infiltration in Lupus-Prone Mice

Frontiers in Immunology, 2021
Lupus nephritis (LN) is one of the most severe manifestations of systemic lupus erythematosus (SLE). Our previous studies demonstrated increased serum and renal Interleukin (IL)-22 in LN patients and MRL/lpr mice.
Lingzhen Hu, Jingyi Hu, Liheng Chen, Yi Zhang, Yi Zhang, Qingqing Wang, Xuyan Yang   +6 more
doaj   +1 more source

Interleukin-22 Deficiency Contributes to Dextran Sulfate Sodium-Induced Inflammation in Japanese Medaka, Oryzias latipes

Frontiers in Immunology, 2021
Mucosal tissue forms the first line of defense against pathogenic microorganisms. Cellular damage in the mucosal epithelium may induce the interleukin (IL)-22-related activation of many immune cells, which are essential for maintaining the mucosal ...
Yoshie Takahashi, Yo Okamura, Nanaki Harada, Mika Watanabe, Hiroshi Miyanishi, Tomoya Kono, Masahiro Sakai, Jun-ichi Hikima   +7 more
doaj   +1 more source

Anti-Psoriatic Effects and IL-22 Targeting Mechanism of Indirubin by Suppressing Keratinocyte Inflammation and Proliferation

Applied Sciences, 2021
Indigo naturalis, which is extracted from the leaves and branches of Baphicacanthus cusia (Nees) Bremek, has traditionally been used to treat psoriasis.
Ly Thi Huong Nguyen, Tae-Woo Oh, Min-Jin Choi, In-Jun Yang, Heung-Mook Shin   +4 more
doaj   +1 more source

The Effect of Herbal Medicinal Products on Psoriasis-Like Keratinocytes

Biomolecules, 2021
Psoriasis is a chronic inflammatory skin disease characterized by hyperproliferation of keratinocytes and expression of pro-inflammatory cytokines in the epidermis.
Fabian Gendrisch, Birgit Haarhaus, Nina Krieger, Karl-Werner Quirin, Christoph M. Schempp, Ute Wölfle   +5 more
doaj   +1 more source

Interleukin-22 Mediates the Chemotactic Migration of Breast Cancer Cells and Macrophage Infiltration of the Bone Microenvironment by Potentiating S1P/SIPR Signaling

Cells, 2020
The interleukin-22 (IL-22) signaling pathway is well known to be involved in the progression of various cancer types but its role in bone metastatic breast cancer remains unclear.
Eun-Young Kim, Bongkun Choi, Ji-Eun Kim, Si-On Park, Sang-Min Kim, Eun-Ju Chang   +5 more
doaj   +1 more source

New Findings on Autoimmune Etiology of Idiopathic Granulomatous Mastitis: Serum IL-17, IL-22 and IL-23 Levels of Patients

Journal of Investigative Surgery, 2021
Background Idiopathic Granulomatous Mastitis (IGM) is a benign chronic inflammatory breast disease that mimics breast cancer, and the etiopathogenesis has not yet been fully evaluated. Autoimmunity has received the most focus as a possible etiology.
Mehmet Saydam, Kerim Bora Yilmaz, Mutlu Sahin, Hamdullah Yanik, Melih Akinci, Ibrahim Yilmaz, Sener Balas, Cem Azili, Mehmet Ali Gulcelik   +8 more
doaj   +1 more source