Results 1 to 10 of about 615,879 (297)
Association of interleukin 22 receptor subunit alpha 1 gene polymorphisms with chronic rhinosinusitis [PDF]
Brazilian Journal of Otorhinolaryngology, 2021 Introduction: Chronic rhinosinusitis is a multifactorial disease whose pathogenesis, influenced by both genetic and environmental factors, is still unclear.
Vanessa R. Pires Dinarte +5 more
doaj +6 more sources
Distinct Expression Patterns of Interleukin-22 Receptor 1 on Blood Hematopoietic Cells in SARS-CoV-2 Infection [PDF]
Frontiers in Immunology, 2022 The new pandemic virus SARS-CoV-2 is characterized by uncontrolled hyper-inflammation in severe cases. As the IL-22/IL-22R1 axis was reported to be involved in inflammation during viral infections, we characterized the expression of IL-22 receptor1, IL ...
Nurhan Albayrak +12 more
doaj +5 more sources
Low Interleukin-22 Binding Protein Is Associated With High Mortality in Alcoholic Hepatitis and Modulates Interleukin-22 Receptor Expression. [PDF]
Clin Transl Gastroenterol, 2020 INTRODUCTION: In alcoholic hepatitis (AH), high interleukin (IL)-22 production is associated with disease improvement, purportedly through enhanced infection resistance and liver regeneration. IL-22 binding protein (BP) binds and antagonizes IL-22 bioactivity, but data on IL-22BP in liver disease suggest a complex interplay ...
Støy S +13 more
europepmc +3 more sources
Ozone-Induced Aryl Hydrocarbon Receptor Activation Controls Lung Inflammation via Interleukin-22 Modulation [PDF]
Frontiers in Immunology, 2020 Airborne ozone exposure causes severe lung injury and inflammation. The aryl hydrocarbon Receptor (AhR) (1), activated in pollutant-induced inflammation, is critical for cytokine production, especially IL-22 and IL-17A.
Chloé Michaudel +14 more
doaj +3 more sources
A polymorphism of interleukin-22 receptor alpha-1 is associated with the development of childhood IgA nephropathy. [PDF]
J Interferon Cytokine Res, 2013 Recent studies suggest that dysregulated innate immunity plays an important role in the pathogenesis of immunoglobulin A nephropathy (IgAN). The interleukin-20 subfamily and its receptor, interleukin-22 receptor alpha-1 (IL-22R1), were recently identified as immunomodulators in human diseases, acting as mediators of mucosal host defense.
Suh JS +5 more
europepmc +4 more sources
Interleukin-22 receptor 1 is expressed in multinucleated giant cells: A study on intestinal tuberculosis and Crohn's disease. [PDF]
World J Gastroenterol, 2019 It is challenging to distinguish intestinal tuberculosis from Crohn's disease due to dynamic changes in epidemiology and similar clinical characteristics. Recent studies have shown that polymorphisms in genes involved in the interleukin (IL)-23/IL-17 axis may affect intestinal mucosal immunity by affecting the differentiation of Th17 cells.To ...
Yu ZQ +4 more
europepmc +3 more sources
The pathogenic role of interleukin-22 and its receptor during UVB-induced skin inflammation.
PLoS ONE, 2017 Recent studies show that IL-22, a cytokine produced by activated CD4+ T cells and NK cells, plays a pathogenic role in acute and chronic skin diseases. While IL-22 is produced by immune cells, the expression of IL-22Rα, the functional subunit of IL-22R ...
Yejin Kim +6 more
doaj +4 more sources
Clinical and Experimental Obstetrics & Gynecology, 2023 Objectives: Immune thrombocytopenia (ITP) is an acquired autoimmune bleeding disease characterized by thrombocytopenia. This review will examine the Notch-aromatic hydrocarbon receptor (AhR)-interleukin-22 (IL-22) signaling pathway regulatory mechanisms ...
Qian-qian Fan, Rong-xia He
doaj +2 more sources
PLoS ONE, 2016 IL-22 is a pro- and anti-inflammatory cytokine that is mainly produced by T cells and NK cells. Recent studies have reported the increased number of IL-22 producing T cells in patients with autoimmune noninfectious uveitis; however, the correlation ...
Yejin Kim +10 more
doaj +5 more sources
مجله كليه طب الكنديBackground: Interleukin-22 is an effector cytokine belongs to the IL-10 family. Signaling of this cytokine control tumor development by boosting cancerous cells growth.
Ikram Khazal Qasim Al-Hasso
doaj +2 more sources