Results 31 to 40 of about 71,336,553 (298)

The Chemokine Receptor CXCR6 Controls the Functional Topography of Interleukin-22 Producing Intestinal Innate Lymphoid Cells [PDF]

open access: yesImmunity, 2014
Interleukin-22 (IL-22) plays a critical role in mucosal defense, although the molecular mechanisms that ensure IL-22 tissue distribution remain poorly understood. We show that the CXCL16-CXCR6 chemokine-chemokine receptor axis regulated group 3 innate lymphoid cell (ILC3) diversity and function.
Satoh-Takayama, Naoko   +6 more
openaire   +2 more sources

The role of interleukin-4 receptor alpha on smooth muscle cells during helminth infection [PDF]

open access: yes, 2011
Includes abstract.Includes bibliographical references (leaves 101-111).Interleukin-4 receptor alpha (IL-4Ra) signaling, mediated by the ligands IL-4 and IL- 13, is important for effective host protection during murine Nippostrongylus brasiliensis (N ...
Brombacher, Tiroyaone M H
core   +1 more source

A comprehensive analysis of interleukin-4 receptor polymorphisms and their association with atopy and IgE regulation in childhood [PDF]

open access: yes, 2004
Background: The interleukin (IL) 4/IL13 pathway is involved in the regulation of IgE production associated with atopic diseases. Numerous polymorphisms have been identified in the coding region of the IL4 receptor alpha chain (IL4Ra) and previous ...
Kabesch, Michael   +7 more
core   +1 more source

Research advances in understanding the role of interleukin-22 in renal disease

open access: yesLinchuang shenzangbing zazhi, 2022
Interleukin 22(IL-22),a member of IL-10 cytokine superfamily,is dominantly produced by innate lymphoid cells and CD4+ T helper subtypes such as Th17 and Th22 cells.And interleukin-22 receptor (IL-22R) is a dimer composed of IL-22R1 and IL-10R2 subunit.IL-
Zhao Dan   +7 more
doaj  

Interleukin-22 predicts severity and death in advanced liver cirrhosis: a prospective cohort study [PDF]

open access: yes, 2012
Background: Interleukin-22 (IL-22), recently identified as a crucial parameter of pathology in experimental liver damage, may determine survival in clinical end-stage liver disease.
Stefan Zeuzem   +35 more
core   +2 more sources

Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22 [PDF]

open access: yesImmunity, 2013
Endogenous tryptophan (Trp) metabolites have an important role in mammalian gut immune homeostasis, yet the potential contribution of Trp metabolites from resident microbiota has never been addressed experimentally. Here, we describe a metabolic pathway whereby Trp metabolites from the microbiota balance mucosal reactivity in mice. Switching from sugar
ZELANTE, TERESA   +12 more
openaire   +5 more sources

Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist : a Mendelian randomisation analysis [PDF]

open access: yes, 2015
Funded by: UK Medical Research Council, British Heart Foundation, UK National Institute for Health Research, National Institute for Health Research Cambridge Biomedical Research Centre, European Research Council, and European Commission Framework ...
D. F. Easton (7608179)   +867 more
core   +3 more sources

Toll/interleukin-1 receptor domains in bacterial and plant immunity

open access: yes, 2023
The Toll/interleukin-1 receptor (TIR) domain is found in animal, plant, and bacterial immune systems. It was first described as a protein-protein interaction module mediating signalling downstream of the Toll-like receptor and interleukin-1 receptor ...
Bostjan Kobe   +9 more
core   +1 more source

Increased expression of interleukin-22 and its receptor is relevant to poor prognosis in laryngeal squamous cell carcinoma

open access: yesMedicine, 2021
Abstract To detect the expression of interlerukin-22 (IL-22) and associated genes and to evaluate their relationship with clinicopathological features and prognosis in laryngeal squamous cell carcinoma (LSCC). The expression of IL-22 and associated genes were evaluated by immunohistochemistry and real time ...
Wenjun Ji   +4 more
openaire   +2 more sources

Some Serum Activity Markers of Airways Inflammation in Difficult-To-Control Asthma Patients

open access: yesActa Medica, 1997
The main aim of the present study was a search for a characteristic serum marker of inflammatory activity in the airways of asthmatics with difficult-to-control disease.
Bohuslav Král   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy