Results 11 to 20 of about 615,879 (297)

Pro-inflammatory signaling by IL-10 and IL-22: bad habit stirred up by interferons? [PDF]

open access: yes, 2013
Interleukin (IL)-10 and IL-22 are key members of the IL-10 cytokine family that share characteristic properties such as defined structural features, usage of IL-10R2 as one receptor chain, and activation of signal transducer and activator of ...
Mühl, Heiko
core   +13 more sources

Interleukin-22 From Type 3 Innate Lymphoid Cells Aggravates Lupus Nephritis by Promoting Macrophage Infiltration in Lupus-Prone Mice

open access: yesFrontiers in Immunology, 2021
Lupus nephritis (LN) is one of the most severe manifestations of systemic lupus erythematosus (SLE). Our previous studies demonstrated increased serum and renal Interleukin (IL)-22 in LN patients and MRL/lpr mice.
Lingzhen Hu   +6 more
doaj   +1 more source

Interleukin-22 Deficiency Contributes to Dextran Sulfate Sodium-Induced Inflammation in Japanese Medaka, Oryzias latipes

open access: yesFrontiers in Immunology, 2021
Mucosal tissue forms the first line of defense against pathogenic microorganisms. Cellular damage in the mucosal epithelium may induce the interleukin (IL)-22-related activation of many immune cells, which are essential for maintaining the mucosal ...
Yoshie Takahashi   +7 more
doaj   +1 more source

Functions of 1,25-dihydroxy vitamin D3, vitamin D3 receptor and interleukin-22 involved in pathogenesis of gout arthritis through altering metabolic pattern and inflammatory responses [PDF]

open access: yesPeerJ, 2021
Background Gouty arthritis (GA) is a common type of inflammatory arthritis. Recent studies demonstrated that 1,25-dihydroxy vitamin D3 (1,25(OH) 2 VD3) and vitamin D3 receptor (VD-R) play a protective role in acute inflammation, but interleukin-22(IL-22)
Yuqi Chen   +6 more
doaj   +2 more sources

IL22RA1 (interleukin 22 receptor, alpha 1) [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on IL22RA1 (interleukin 22 receptor, alpha 1), with data on DNA, on the protein encoded, and where the gene is implicated.
Gelebart, P, Lai, R
openaire   +2 more sources

Interleukin-22 and keratinocytes; pathogenic implications in skin inflammation

open access: yesExploration of Immunology, 2021
Interleukin (IL)-22 is produced from immune cells such as T helper (Th)22 cells, Th17/22 cells, and group 3 innate lymphoid cells. IL-22 signals via the IL-22 receptor 1 (IL-22R1) and the IL-10 receptor 2 (IL-10R2).
Masutaka Furue, Mihoko Furue
doaj   +1 more source

From intestinal dysbiosis to alcohol-associated liver disease [PDF]

open access: yesClinical and Molecular Hepatology, 2020
Alcohol-associated intestinal dysbiosis and bacterial overgrowth can lead to a dysregulation of tryptophan metabolism and lower production of indoles. Several of these indole derivatives are aryl hydrocarbon receptor ligands that, in turn, are involved ...
Beatriz Garcia Mendes, Bernd Schnabl
doaj   +1 more source

Fetal skin as a pro-inflammatory organ: Evidence from a primate model of chorioamnionitis. [PDF]

open access: yes, 2017
BackgroundIntrauterine infection is a primary cause of preterm birth and fetal injury. The pro-inflammatory role of the fetal skin in the setting of intrauterine infection remains poorly characterized. Whether or not inflammation of the fetal skin occurs
Boonkasidecha, Suppawat   +4 more
core   +10 more sources

The role of interleukin-22 in lung health and its therapeutic potential for COVID-19

open access: yesFrontiers in Immunology, 2022
Although numerous clinical trials have been implemented, an absolutely effective treatment against coronavirus disease 2019 (COVID-19) is still elusive.
Si Fang   +4 more
doaj   +1 more source

Crystal structure of a soluble decoy receptor IL‐22BP bound to interleukin‐22 [PDF]

open access: yesFEBS Letters, 2009
MINT‐7010533: IL‐22 BP (uniprotkb:Q969J5) and IL‐22 (uniprotkb:Q9GZX6) bind (MI:0407) by X‐ray crystallography (MI:0114)
de Moura, Patricia Ribeiro   +7 more
openaire   +2 more sources

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