IL22RA1 (interleukin 22 receptor, alpha 1) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on IL22RA1 (interleukin 22 receptor, alpha 1), with data on DNA, on the protein encoded, and where the gene is implicated.
Gelebart, P, Lai, R
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Low Interleukin-22 Binding Protein Is Associated With High Mortality in Alcoholic Hepatitis and Modulates Interleukin-22 Receptor Expression [PDF]
Clinical and Translational Gastroenterology, 2020 INTRODUCTION: In alcoholic hepatitis (AH), high interleukin (IL)-22 production is associated with disease improvement, purportedly through enhanced infection resistance and liver regeneration.
Støy, Sidsel +13 more
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Crystal structure of a soluble decoy receptor IL‐22BP bound to interleukin‐22 [PDF]
FEBS Letters, 2009 MINT‐7010533: IL‐22 BP (uniprotkb:Q969J5) and IL‐22 (uniprotkb:Q9GZX6) bind (MI:0407) by X‐ray crystallography (MI:0114)
de Moura, Patricia Ribeiro +7 more
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A Polymorphism of Interleukin-22 Receptor Alpha-1 Is Associated with the Development of Childhood IgA Nephropathy [PDF]
Journal of Interferon & Cytokine Research, 2013 Recent studies suggest that dysregulated innate immunity plays an important role in the pathogenesis of immunoglobulin A nephropathy (IgAN). The interleukin-20 subfamily and its receptor, interleukin-22 receptor alpha-1 (IL-22R1), were recently identified as immunomodulators in human diseases, acting as mediators of mucosal host defense.
Jin-Soon, Suh +5 more
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Interleukin-22 Forms Dimers that are Recognized by Two Interleukin-22R1 Receptor Chains [PDF]
Biophysical Journal, 2008 Interleukin-22 (IL-22) is a class 2 cytokine whose primary structure is similar to that of interleukin 10 (IL-10) and interferon-gamma (IFN-gamma). IL-22 induction during acute phase immune response indicates its involvement in mechanisms of inflammation.
de Oliveira Neto, Mario +8 more
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Interleukin-22 receptor 1 is expressed in multinucleated giant cells: A study on intestinal tuberculosis and Crohn's disease [PDF]
World Journal of Gastroenterology, 2019 It is challenging to distinguish intestinal tuberculosis from Crohn's disease due to dynamic changes in epidemiology and similar clinical characteristics. Recent studies have shown that polymorphisms in genes involved in the interleukin (IL)-23/IL-17 axis may affect intestinal mucosal immunity by affecting the differentiation of Th17 cells.To ...
Yu, Zi-Qi +4 more
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ES-62 protects against collagen-induced arthritis by resetting interleukin-22 towards resolution of inflammation in the joints [PDF]
, 2014 Objective. The parasitic worm–derived immunomodulator ES-62 protects against disease in the mouse collagen-induced arthritis (CIA) model of rheumatoid arthritis (RA) by suppressing pathogenic interleukin-17 (IL-17) responses. The Th17 associated cytokine
Al-Riyami, Lamyaa +4 more
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Interleukin-22 and keratinocytes; pathogenic implications in skin inflammation
Exploration of Immunology, 2021 Interleukin (IL)-22 is produced from immune cells such as T helper (Th)22 cells, Th17/22 cells, and group 3 innate lymphoid cells. IL-22 signals via the IL-22 receptor 1 (IL-22R1) and the IL-10 receptor 2 (IL-10R2).
Masutaka Furue, Mihoko Furue
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From intestinal dysbiosis to alcohol-associated liver disease [PDF]
Clinical and Molecular Hepatology, 2020 Alcohol-associated intestinal dysbiosis and bacterial overgrowth can lead to a dysregulation of tryptophan metabolism and lower production of indoles. Several of these indole derivatives are aryl hydrocarbon receptor ligands that, in turn, are involved ...
Beatriz Garcia Mendes, Bernd Schnabl
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Functions of 1,25-dihydroxy vitamin D3, vitamin D3 receptor and interleukin-22 involved in pathogenesis of gout arthritis through altering metabolic pattern and inflammatory responses [PDF]
PeerJ, 2021 Background Gouty arthritis (GA) is a common type of inflammatory arthritis. Recent studies demonstrated that 1,25-dihydroxy vitamin D3 (1,25(OH) 2 VD3) and vitamin D3 receptor (VD-R) play a protective role in acute inflammation, but interleukin-22(IL-22)
Yuqi Chen +6 more
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