Results 21 to 30 of about 576,409 (261)

Role of Interleukin-22 in ulcerative colitis

Biomedicine & Pharmacotherapy, 2023
Ulcerative Colitis (UC) is a chronic disease, in the progression of which an immune overreaction may play an important role. IL-22 is a member of the IL-10 superfamily of cytokines and is pleiotropic in immune regulation and inflammatory responses. IL-22 can produce protective effects, promote wound healing and tissue regeneration, while it can also ...
Nan Zhao, Chuanguo Liu, Ning Li, Shuang Zhou, Yuting Guo, Shihua Yang, Huimin Liu   +6 more
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Interleukin-22 Influences the Th1/Th17 Axis

Frontiers in Immunology, 2021
Interleukin-22 (IL-22) is secreted by a wide range of immune cells and its downstream effects are mediated by the IL-22 receptor, which is present on non-immune cells in many organs throughout the body.
Hannes Lindahl, Tomas Olsson
doaj   +1 more source

Lactobacillus delivery of bioactive interleukin-22 [PDF]

Microbial Cell Factories, 2017
Interleukin-22 (IL-22) plays a prominent role in epithelial regeneration and dampening of chronic inflammatory responses by protecting intestinal stem cells from immune-mediated tissue damage. IL-22 has a considerable therapeutic potential in graft-versus-host disease (GVHD), which is a frequent and challenging complication following allogeneic stem ...
Lin, Yin, Krogh-Andersen, Kasper, Hammarström, Lennart, Marcotte, Harold   +3 more
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Pivotal Role of IL-22 Binding Protein in the Epithelial Autoregulation of Interleukin-22 Signaling in the Control of Skin Inflammation

Frontiers in Immunology, 2018
Disruption of skin homeostasis can lead to inflammatory cutaneous diseases resulting from the dysregulated interplay between epithelial keratinocytes and immune cells.
Tomohiro Fukaya, Tomohiro Fukaya, Takehito Fukui, Takehito Fukui, Tomofumi Uto, Tomofumi Uto, Hideaki Takagi, Hideaki Takagi, Junta Nasu, Junta Nasu, Noriaki Miyanaga, Noriaki Miyanaga, Keiichi Arimura, Keiichi Arimura, Takeshi Nakamura, Takeshi Nakamura, Haruhiko Koseki, Narantsog Choijookhuu, Yoshitaka Hishikawa, Katsuaki Sato, Katsuaki Sato   +20 more
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Analysis of Interleukin 22 Gene Expression in Helicobacter pylori-Infected Patients With Inflammation and Peptic Ulcer Compared to Uninfected Controls [PDF]

Journal of Shahrekord University of Medical Sciences
Background and aims: Inflammation is a key feature of Helicobacter pylori infection and its associated complications, gastritis, and gastrointestinal ulcers.
Mehrnoosh Haghighian, Noosha Zia Jahromi, Ghorbanali Rahimian   +2 more
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Interleukin-22 acts as a mitochondrial protector

Theranostics, 2020
Interleukin (IL)-22 has been increasingly recognized as a promising therapeutic option for various types of diseases. This commentary summarizes the novel mechanistic aspects of IL-22 for the treatment of liver diseases including the study by Chen et al.
Hwang, Seonghwan, Feng, Dechun, Gao, Bin
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Characterization of IL-22 Bioactivity and IL-22-Positive Cells in Grass Carp Ctenopharyngodon idella

Frontiers in Immunology, 2020
Interleukin (IL)-22 plays an important role in regulating inflammation and clearance of infectious pathogens. IL-22 homologs have been discovered in fish, but the functions and sources of IL-22 have not been fully characterized.
Yibin Yang, Yibin Yang, Yibin Yang, Yibin Yang, Junya Wang, Junya Wang, Junya Wang, Jiawen Xu, Jiawen Xu, Jiawen Xu, Qin Liu, Qin Liu, Qin Liu, Zixuan Wang, Zixuan Wang, Zixuan Wang, Xiaozhen Zhu, Xiaozhen Zhu, Xiaozhen Zhu, Xiaohui Ai, Qian Gao, Qian Gao, Qian Gao, Xinhua Chen, Jun Zou, Jun Zou, Jun Zou, Jun Zou   +27 more
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Anti-Psoriatic Effects and IL-22 Targeting Mechanism of Indirubin by Suppressing Keratinocyte Inflammation and Proliferation

Applied Sciences, 2021
Indigo naturalis, which is extracted from the leaves and branches of Baphicacanthus cusia (Nees) Bremek, has traditionally been used to treat psoriasis.
Ly Thi Huong Nguyen, Tae-Woo Oh, Min-Jin Choi, In-Jun Yang, Heung-Mook Shin   +4 more
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Interleukin-22 Attenuates Acute Pancreatitis-Associated Intestinal Mucosa Injury in Mice via STAT3 Activation

Gut and Liver, 2021
Background/Aims: Interleukin-22 (IL-22) is an important cytokine maintaining homeostasis at barrier surfaces. In this study, the role of IL-22 in acute pancreatitis-associated intestinal injury was further explored.
Jinxia Bai, Jinyun Bai, Meng Yang
doaj   +1 more source

Biological and pathological activities of interleukin-22 [PDF]

Journal of Molecular Medicine, 2016
Interleukin (IL)-22, a member of the IL-10 family, is a cytokine secreted by several types of immune cells including IL-22(+)CD4(+) T cells (Th22) and IL-22 expressing innate leukocytes (ILC22). Recent studies have demonstrated that IL-22 is a key component in mucosal barrier defense, tissue repair, epithelial cell survival, and proliferation ...
Mirna, Perusina Lanfranca, Yanwei, Lin, Jingyuan, Fang, Weiping, Zou, Timothy, Frankel   +4 more
openaire   +2 more sources