Results 21 to 30 of about 4,022,531 (291)

Expression and significance of interleukin-17 and interleukin-22 in the serum and the lower esophageal sphincter of patients with achalasia

The Saudi Journal of Gastroenterology, 2018
Background/Aim: We studied the expression of interleukin-17 and interleukin-22 in the serum and the lower esophageal sphincter (LES) in healthy individuals and in patients diagnosed with achalasia (AC) to gain a better understanding of the ...
Zeyu Wang, Jun Zhang, Jianwei Mi, Huihui Ma, Dongqiang Zhao   +4 more
doaj   +1 more source

Distinct Expression Patterns of Interleukin-22 Receptor 1 on Blood Hematopoietic Cells in SARS-CoV-2 Infection

Frontiers in Immunology, 2022
The new pandemic virus SARS-CoV-2 is characterized by uncontrolled hyper-inflammation in severe cases. As the IL-22/IL-22R1 axis was reported to be involved in inflammation during viral infections, we characterized the expression of IL-22 receptor1, IL ...
Nurhan Albayrak, Carmen Orte Cano, Sina Karimi, David Dogahe, Anne Van Praet, Audrey Godefroid, Véronique Del Marmol, David Grimaldi, Benjamin Bondue, Jean-Paul Van Vooren, Jean-Paul Van Vooren, Françoise Mascart, Véronique Corbière   +12 more
doaj   +1 more source

Elevated circulating levels of IL-21 and IL-22 define a cytokine signature profile in type 2 autoimmune hepatitis patients

Annals of Hepatology, 2016
Background and aims. Autoimmune hepatitis (AIH) is a chronic inflammatory condition of the liver in which the immunological mechanisms involved in tissue destruction and/or repair are still unclear. Different pro-inflammatory cytokines have been shown to
Pablo Thomas-Dupont, José M. Remes-Troche, Irma Y. Izaguirre-Hernández, Luis A. Sánchez-Vargas, Mathywz de J. Maldonado-Rentería, Karina G. Hernández-Flores, Aldo Torre, Elidé Bravo-Sarmiento, Héctor Vivanco-Cid   +8 more
doaj   +1 more source

Early production of IL-22 but not IL-17 by peripheral blood mononuclear cells exposed to live Borrelia burgdorferi: the role of monocytes and interleukin-1 [PDF]

, 2010
If insufficiently treated, Lyme borreliosis can evolve into an inflammatory disorder affecting skin, joints, and the CNS. Early innate immunity may determine host responses targeting infection. Thus, we sought to characterize the immediate cytokine storm
Nicole Darsow, Kind, Peter, Rudloff, Ina, Klaus-Peter Hunfeld, Katharina Horn, Itamar Goren, Urs Christen, Kraiczy Peter, Horn Katharina, Pfeilschifter, Josef (Prof. Dr.), Mühl Heiko, Koehl Ulrike, Peter Kind, Goren Itamar, Pfeilschifter, Josef, Peter Kraiczy, Rudloff Ina, Goren, Itamar, Mühl, Heiko, Darsow, Nicole, Christen Urs, Kraiczy, Peter, Christen, Urs, Holdener, Martin, Horn, Katharina, Hunfeld, Klaus-Peter, Ulrike Koehl, Hunfeld Klaus-Peter, Heiko Mühl, Ina Rudloff, Malte Bachmann, Martin Holdener, Holdener Martin, Koehl, Ulricke, Bachmann Malte, Darsow Nicole, Kind Peter, Köhl, Ulrike, Josef Pfeilschifter, Bachmann, Malte, Pfeilschifter Josef   +40 more
core   +1 more source

Role of Interleukin-22 in ulcerative colitis

Biomedicine & Pharmacotherapy, 2023
Ulcerative Colitis (UC) is a chronic disease, in the progression of which an immune overreaction may play an important role. IL-22 is a member of the IL-10 superfamily of cytokines and is pleiotropic in immune regulation and inflammatory responses. IL-22 can produce protective effects, promote wound healing and tissue regeneration, while it can also ...
Nan Zhao, Chuanguo Liu, Ning Li, Shuang Zhou, Yuting Guo, Shihua Yang, Huimin Liu   +6 more
openaire   +2 more sources

Pro-inflammatory signaling by IL-10 and IL-22: bad habit stirred up by interferons? [PDF]

, 2013
Interleukin (IL)-10 and IL-22 are key members of the IL-10 cytokine family that share characteristic properties such as defined structural features, usage of IL-10R2 as one receptor chain, and activation of signal transducer and activator of ...
Heiko Mühl, Heiko eMühl, Mühl, Heiko
core   +1 more source

Cytokines (interleukin-9, IL-17, IL-22, IL-25 and IL-33) and asthma

Advanced Biomedical Research, 2014
Asthma is a reversible airway obstruction that is characterized by constriction of airway smooth muscle, hyper secretion of mucus, edema and airway hyper responsiveness (AHR), mucus secretion and thickening of the basement membrane underlying the airway ...
Rahim Farahani, Roya Sherkat, Mazdak Ganjalikhani Hakemi, Nahid Eskandari, Reza Yazdani   +4 more
doaj   +1 more source

Tristetraprolin regulation of interleukin-22 production [PDF]

Scientific Reports, 2015
AbstractInterleukin (IL)-22 is a STAT3-activating cytokine displaying characteristic AU-rich elements (ARE) in the 3′-untranslated region (3′-UTR) of its mRNA. This architecture suggests gene regulation by modulation of mRNA stability. Since related cytokines undergo post-transcriptional regulation by ARE-binding tristetraprolin (TTP), the role of this
Härdle, Lorena, Bachmann, Malte, Bollmann, Franziska, Pautz, Andrea, Schmid, Tobias, Eberhardt, Wolfgang, Kleinert, Hartmut, Pfeilschifter, Josef, Mühl, Heiko   +8 more
openaire   +3 more sources

Interleukin-22 acts as a mitochondrial protector

Theranostics, 2020
Interleukin (IL)-22 has been increasingly recognized as a promising therapeutic option for various types of diseases. This commentary summarizes the novel mechanistic aspects of IL-22 for the treatment of liver diseases including the study by Chen et al.
Hwang, Seonghwan, Feng, Dechun, Gao, Bin
openaire   +2 more sources

Role of Interleukin-22 in liver diseases [PDF]

Inflammation Research, 2014
Interleukin (IL)-22, originally referred to as IL-TIF for IL-10-related T cell-derived inducible factor, is a member of the IL-10-like cytokine family. IL-22 is highly expressed by Th17 cells and is tightly linked to chronic inflammation, including inflammatory bowel disease and local intestinal inflammation among others.A PubMed and Web of Science ...
Pan, Chun-xiao, Tang, Jie, Wang, Xiao-yu, Wu, Fan-rong, Ge, Jin-fang, Chen, Fei-hu   +5 more
openaire   +2 more sources