Results 51 to 60 of about 539,865 (299)

Interleukin-22 ameliorates liver fibrosis through miR-200a/beta-catenin [PDF]

open access: yes, 2016
IL-22 ameliorates liver fibrosis by inhibiting hepatic stellate cells (HSC), and loss of miR-200a is associated with the development of liver fibrosis. The study aimed to investigate the interplay between IL-22 and miR-200a in regulating liver fibrosis ...
Hu, Bang-li   +7 more
core   +2 more sources

T helper cell subsets specific for pseudomonas aeruginosa in healthy individuals and patients with cystic fibrosis [PDF]

open access: yes, 2014
Background: We set out to determine the magnitude of antigen-specific memory T helper cell responses to Pseudomonas aeruginosa in healthy humans and patients with cystic fibrosis.
AJ Vallis   +36 more
core   +3 more sources

Interleukin-22 in alcoholic hepatitis and beyond

open access: yesHepatology International, 2020
Alcoholic hepatitis (AH) is a clinical syndrome characterized by jaundice and progressive inflammatory liver injury in patients with a history of prolonged periods of excess alcohol consumption and recent heavy alcohol abuse. Severe AH is a life-threatening form of alcohol-associated liver disease with a high short-term mortality rate around 30-50% at ...
Xiaogang, Xiang   +4 more
openaire   +3 more sources

Restoration of Type 17 immune signaling is not sufficient for protection during influenza-associated pulmonary aspergillosis

open access: yesFrontiers in Immunology
IntroductionInfluenza-associated pulmonary aspergillosis (IAPA) is a severe complication of influenza infection that occurs in critically ill patients and results in higher mortality compared to influenza infection alone.
Aijaz Ahmad   +6 more
doaj   +1 more source

MALDI-MSI for the analysis of a 3D tissue-engineered psoriatic skin model [PDF]

open access: yes, 2016
MALDI-MS Imaging is a novel label-free technique that can be used to visualize the changes in multiple mass responses following treatment. Following treatment with proinflammatory cytokine interleukin-22 (IL-22), the epidermal differentiation of ...
Auger   +23 more
core   +1 more source

Research advances in understanding the role of interleukin-22 in renal disease

open access: yesLinchuang shenzangbing zazhi, 2022
Interleukin 22(IL-22),a member of IL-10 cytokine superfamily,is dominantly produced by innate lymphoid cells and CD4+ T helper subtypes such as Th17 and Th22 cells.And interleukin-22 receptor (IL-22R) is a dimer composed of IL-22R1 and IL-10R2 subunit.IL-
Zhao Dan   +7 more
doaj  

Candida albicans Colonizes and Disseminates to the Gastrointestinal Tract in the Presence of the Microbiota in a Severe Combined Immunodeficient Mouse Model

open access: yesFrontiers in Microbiology, 2021
Candida albicans is the leading cause of candidemia or other invasive candidiasis. Gastrointestinal colonization has been considered as the primary source of candidemia. However, few established mouse models that mimic this infection route are available.
Chien-Hsiung Pan   +11 more
doaj   +1 more source

Interleukin 22 in Liver Injury, Inflammation and Cancer [PDF]

open access: yesInternational Journal of Biological Sciences, 2020
Interleukin 22(IL-22), a member of the IL-10 cytokine family and is an emerging CD4+Th cytokine that plays an important role in anti-microbial defense, homeostasis and tissue repair. We are interested in IL-22 as it has the double function of suppressing or encouraging inflammation in various disease models including hepatic inflammation. As a survival
Wu, Ye   +6 more
openaire   +2 more sources

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider   +4 more
wiley   +1 more source

Cytochrome P4501-inhibiting chemicals amplify aryl hydrocarbon receptor activation and IL-22 production in T helper 17 cells [PDF]

open access: yes, 2018
The aryl hydrocarbon receptor (AHR)controls interleukin 22 production by T helper 17 cells (Th17). IL-22contributes to intestinalhomeostasis but has also been implicated inchronic inflammatory disorders and colorectal cancer, highlighting the need for ...
Das, S   +4 more
core   +1 more source

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