Results 71 to 80 of about 539,865 (299)
Biomedicines, 2021 Nonalcoholic fatty liver disease (NAFLD) represents one of the most common liver disorders and can progress into a series of liver diseases, including nonalcoholic steatohepatitis (NASH), fibrosis, cirrhosis, and even liver cancer. Interleukin-22 (IL-22),
Wenjing Zai +3 more
doaj +1 more source
Systemic levels of IL-23 are strongly associated with disease activity in rheumatoid arthritis but not spondyloarthritis [PDF]
, 2009 Objectives Th17 cells are an effector T-cell population that plays a role in chronic inflammatory conditions and is dependent on IL-23 for their survival and expansion. More recently, a genetic association was discovered between polymorphisms in the gene
De Keyser, Filip +8 more
core +1 more source
Crystal Structure of Recombinant Human Interleukin-22 [PDF]
Structure, 2002 Interleukin-22 (IL-10-related T cell-derived inducible factor/IL-TIF/IL-22) is a novel cytokine belonging to the IL-10 family. Recombinant human IL-22 (hIL-22) was found to activate the signal transducers and activators of transcription factors 1 and 3 as well as acute phase reactants in several hepatoma cell lines, suggesting its involvement in the ...
Nagem, Ronaldo Alves Pinto +5 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Interleukin-22, a potent target for treatment of non-autoimmune diseases
Human Vaccines & Immunotherapeutics, 2018 Interleukin −22 (IL-22) is a member of interleukin-10 (IL-10) family cytokines that is produced by different types of lymphocytes included in both innate and adaptive immune systems. These lymphocytes include activated T cells, most notably Th17 and Th22
Yue Zheng, Tong Li
doaj +1 more source
Interleukin‐22 and CD160 play additive roles in the host mucosal response to Clostridium difficile infection in mice [PDF]
, 2015 Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/110834/1/imm12414 ...
Bergin, Ingrid L. +9 more
core +1 more source
FEBS Open Bio, EarlyView.The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source
Inhibitory role of trichostatin A in secretion function of mouse peripheral lymph node cells
Di-san junyi daxue xuebao, 2020 Objective To investigate the role of trichostatin A (TSA) and its mechanism on secretory function of peripheral lymph node cells in mice. Methods The adult male C57BL/6 mice were sacrificed and their peripheral lymph nodes (LN), mesenteric lymph nodes ...
LIU Yijia +8 more
doaj +1 more source
Bcl-3 deficiency protects against dextran-sodium sulphate-induced colitis in the mouse [PDF]
, 2013 Bcl-3 is a member of the IκB family of proteins and is an essential negative regulator of Toll-like receptor induced responses. Recently, a single nucleotide polymorphism associated with reduced Bcl-3 gene expression has been identified as a potential ...
Araki +26 more
core +1 more source
Aging and Cancer, EarlyView.This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source