Interleukin-17 Receptor D in Physiology, Inflammation and Cancer [PDF]
Frontiers in Oncology, 2021 Interleukin-17 receptor D (IL-17RD) is an evolutionarily conserved member of the IL-17 receptor family. Originally identified as a negative regulator of fibroblast growth factor (FGF) signaling under the name of Sef (Similar expression to FGF genes), IL ...
Charlotte Girondel +4 more
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Endometrial senescence is mediated by interleukin 17 receptor B signaling [PDF]
Cell Communication and SignalingBackground We previously identified Il17RB, a member of the IL17 superfamily, as a candidate marker gene for endometrial aging. While IL17RB has been linked to inflammation and malignancies in several organ systems, its function in the endometrium has ...
Keiko Kawamura +9 more
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Impact of Adalimumab Treatment on Interleukin-17 and Interleukin-17 Receptor Expression in Skin and Synovium of Psoriatic Arthritis Patients with Mild Psoriasis [PDF]
Biomedicines, 2022 Interleukin (IL)-17 and tumor necrosis factor-alpha (TNF)-α are key players in psoriatic arthritis (PsA) pathogenesis. While both cytokines can be therapeutically targeted with beneficial clinical outcome, it is unclear whether inhibiting one cytokine ...
Janne W. Bolt +9 more
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Interleukin 17 receptor A modulates monocyte subsets and macrophage generation in vivo. [PDF]
PLoS ONE, 2014 Interleukin (IL)-17A signaling via Interleukin 17 receptor A (Il17ra) contributes to the inflammatory host response by inducing recruitment of innate immune cells, but also plays a role in homeostatic neutrophilic granulocyte regulation.
Shuwang Ge +7 more
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Interleukin-17 Cytokines and Receptors: Potential Amplifiers of Tendon Inflammation [PDF]
Frontiers in Bioengineering and Biotechnology, 2021 Interleukin (IL)-17A, a pro-inflammatory cytokine that is linked to the pathology of several inflammatory diseases, has been shown to be upregulated in early human tendinopathy and to mediate inflammatory and tissue remodelling events.
Jolet Y. Mimpen +3 more
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Interleukin-17 receptor D (Sef) is a multi-functional regulator of cell signaling [PDF]
Cell Communication and Signaling, 2021 Interleukin-17 receptor D (IL17RD or IL-17RD) also known as Sef (similar expression to fibroblast growth factor), is a single pass transmembrane protein that is reported to regulate several signaling pathways .
Shivangi Pande +2 more
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B cell-intrinsic interleukin 17 receptor A signaling supports the establishment of chronic murine gammaherpesvirus 68 infection [PDF]
Journal of VirologyThe human-specific gammaherpesviruses Epstein-Barr virus and Kaposi’s sarcoma-associated herpesvirus infect >95% of all adults, establish lifelong infections, and are associated with multiple different cancers, including B-cell lymphomas.
Sheikh Tahir Majeed +3 more
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Downregulation of chicken interleukin-17 receptor A during Eimeria infection. [PDF]
Infect Immun, 2014 ABSTRACT Both interleukin-17A (IL-17A) and IL-17F are proinflammatory cytokines that have an important role in intestinal homeostasis via receptor signaling. These cytokines have been characterized in chickens, but very little is known about their receptors and their functional activity.
Kim WH +9 more
europepmc +4 more sources
Interleukin 17 Receptor Gene Polymorphism in Periimplantitis and Chronic Periodontitis
Acta Medica Iranica, 2013 Gene polymorphism of cytokines influencing their function has been known as a contributing factor in the pathogenesis of inflammatory diseases of the tooth and implant supporting tissues. The aim of this study was to investigate the association of IL-17R
Mahdi Kadkhodazadeh +4 more
doaj +4 more sources
The deubiquitinase A20 mediates feedback inhibition of interleukin-17 receptor signaling. [PDF]
Sci Signal, 2013 Inhibition of an inflammatory cytokine signaling pathway by A20 at the receptor may play a role in preventing autoimmunity.
Garg AV +4 more
europepmc +4 more sources