Results 1 to 10 of about 143,068 (301)

Evaluation of the Association Between Postpartum Hemorrhage and Antidepressant Use: A Mendelian Randomization Study

Drugs - Real World Outcomes
Background The relationship between antidepressants, depression, and the incidence of postpartum hemorrhage (PPH) has been reported in observational studies, but the causal link between these factors remains unknown.
Zhenzhen Chen, Qingqing Lv, Shiteng Lin, Wanlong Lin, Wei Zhuang   +4 more
doaj   +1 more source

Mendelian Randomization Applied to Neurology

Neurology
The Mendelian randomization (MR) paradigm allows for causal inferences to be drawn using genetic data. In recent years, the expansion of well-powered publicly available genetic association data related to phenotypes such as brain tissue gene expression, brain imaging, and neurologic diseases offers exciting opportunities for the application of MR in ...
Eloi Gagnon, Iyas Daghlas, Loukas Zagkos, Muralidharan Sargurupremraj, Marios K. Georgakis, Christopher D. Anderson, Helene T. Cronje, Stephen Burgess, Benoit J. Arsenault, Dipender Gill   +9 more
openaire   +2 more sources

Managing the exponential growth of Mendelian randomization studies

Addiction
[No abstract]
Marcus R Munafo, Jamie Brown, Marita Hefler, George Davey Smith   +3 more
openaire   +9 more sources

Commentary: The concept of 'Mendelian Randomization' [PDF]

International Journal of Epidemiology, 2004
Duncan C, Thomas, David V, Conti
openaire   +2 more sources

Relationship Between Migraine and Alzheimer's Disease: A Study of Mendelian Randomization

Brain and Behavior
Background Given inconsistent evidence regarding the migraine‐Alzheimer's disease association, this Mendelian randomization (MR) study examines their potential causal relationship. Methods GWAS summary statistics for migraine and Alzheimer's disease were
Ran Bi, Weimin Zhao, Jiaoxuan Li, Songji Han, Haotian Qi, Jian Liu, Jinpu Wu, Shengxian Xu, Zhongda Sun, Zhenru Liu   +9 more
doaj   +1 more source

Bidirectional Mendelian randomization identifies differential causal associations between inflammatory cytokines and lung cancer subtypes

Discover Oncology
Highlights Mendelian randomization study on relationships between inflammatory factors and lung cancer risk. Bidirectional two-sample Mendelian randomization approach, utilizing Genome-Wide Association Studies data for two primary lung cancer subtypes ...
Menglu Sun, Xue Gao
doaj   +1 more source

Mendelian randomization: the challenge of unobserved environmental confounds [PDF]

International Journal of Epidemiology, 2019
Koellinger, Philipp D, de Vlaming, Ronald   +1 more
openaire   +3 more sources

Association of Physical Activity with Asthma and Chronic Obstructive Pulmonary Disease and Mediation of Frailty: Mendelian Randomization Analyses

International Journal of COPD
Nanxin Chen,1 Xuejie Si,2 Jun Wang,2 Wenjing Chen2 1First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, 250014, People’s Republic of China; 2Department of Respiratory and Critical Care Medicine, The ...
Chen N, Si X, Wang J, Chen W
doaj  

Alzheimer disease and lichen planus: A Mendelian randomization analysis. [PDF]

Medicine (Baltimore)
Huang W, Xiao L.
europepmc   +1 more source

Commentary: Mendelian randomization and women’s health [PDF]

International Journal of Epidemiology, 2019
Censin, JC, Bovijn, J, Holmes, MV, Lindgren, CM   +3 more
openaire   +2 more sources