Results 41 to 50 of about 150,483 (315)

Causal relationship between air pollution, lung function, gastroesophageal reflux disease, and non-alcoholic fatty liver disease: univariate and multivariate Mendelian randomization study

Frontiers in Public Health
BackgroundThe association between air pollution, lung function, gastroesophageal reflux disease, and Non-alcoholic fatty liver disease (NAFLD) remains inconclusive. Previous studies were not convincing due to confounding factors and reverse causality. We
Runmin Cao, Honghe Jiang, Yurun Zhang, Ying Guo, Weibin Zhang   +4 more
doaj   +1 more source

Dairy Consumption and Body Mass Index Among Adults: Mendelian Randomization Analysis of 184802 Individuals from 25 Studies [PDF]

, 2018
BACKGROUND—Associations between dairy intake and body mass index (BMI) have been inconsistently observed in epidemiological studies, and the causal relationship remains ill defined.
Mendelian Randomization of Dairy Consumption Working Group
core   +1 more source

Results of Mendelian randomization analysis of intelligence on PAS.

, 2023
Results of Mendelian randomization analysis of intelligence on PAS.
Tianmin Zhu (2206318), Furong Zhang (5690462), Yushan Shi (16440272), Zhangmeng Xu (16726372), Guorong Qiu (16726375), Duoduo Yu (16726378), Guogang Dai (9228115)   +6 more
core   +1 more source

Mendelian randomization approach.

, 2013
Mendelian randomization approach.
Akshay Anand (118579), Amod Gupta (118583), Suresh Kumar Sharma (118585), Sudesh Prabhakar (118584), Neel Kamal Sharma (118581), Ramandeep Singh (118586), Wei Chen (23863)   +6 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Rheumatoid arthritis and risk of lung diseases in East Asians and Europeans: Evidence from a Mendelian randomization study

SAGE Open Medicine
Background: Rheumatoid arthritis might increase the risk of lung diseases, such as interstitial lung disease and lung cancer. However, the causal relationships remained unclear.
Shengkai Zhang, Xiang Huang, Meiying Huang, Xinhan Peng, Qiuye Cao, Yi Lan   +5 more
doaj   +1 more source

Concept of Mendelian randomization.

, 2015
Concept of Mendelian randomization.
Albert Hofman (107303), Oscar H. Franco (303354), Marte C. Liefaard (765482), Anna Vitezova (733786), Abbas Dehghan (174878), Jessica C. Kiefte-de Jong (591843), Symen Ligthart (701678), M. Carola Zillikens (152896), André G. Uitterlinden (2213413)   +8 more
core   +1 more source

Mendelian randomization in nutritional epidemiology [PDF]

Nutrition Reviews, 2009
Nutritional epidemiology aims to identify dietary and lifestyle causes for human diseases. Causality inference in nutritional epidemiology is largely based on evidence from studies of observational design, and may be distorted by unmeasured or residual confounding and reverse causation.
openaire   +2 more sources

Smoking and stroke: A mendelian randomization study [PDF]

Annals of Neurology, 2019
We used the Mendelian randomization design to explore the potential causal association of smoking with ischemic stroke and intracerebral hemorrhage using summary statistics data for 34,217 ischemic stroke cases and 404,630 noncases, and 1,545 cases of intracerebral hemorrhage and 1,481 noncases.
Larsson, Susanna C, Burgess, Stephen, Michaëlsson, Karl   +2 more
openaire   +4 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source