Results 31 to 40 of about 150,483 (315)

Investigating the causal impact of gut microbiota on glioblastoma: a bidirectional Mendelian randomization study

BMC Genomics, 2023
Background Currently, the influence of microbiota on the occurrence, progression, and treatment of cancer is a topic of considerable research interest. Therefore, based on the theory of the gut-brain axis proved by previous studies, our objective was to ...
Chuan Zeng, Chaolong Zhang, Chunming He, Haimin Song   +3 more
doaj   +1 more source

Mendelian randomization Asthma exposure pain outcome.

, 2023
Mendelian randomization Asthma exposure pain outcome.
James A. Perry (10515389), Siobhan M. Schabrun (11929656), Susan G. Dorsey (11780093), Kathryn Ward (17174753), Evelina Mocci (374296), Seth A. Ament (9427801), Cynthia Renn (17174756), Angela Starkweather (10581244), Laura S. Stone (9392671)   +8 more
core   +1 more source

The role of smoking and alcohol in mediating the effect of gastroesophageal reflux disease on lung cancer: A Mendelian randomization study

Frontiers in Genetics, 2023
Observational studies have suggested a positive association between gastroesophageal reflux disease and lung cancer, but due to the existence of confounders, it remains undetermined whether gastroesophageal reflux disease (GERD) has a causal association ...
Jing Yang, Duorui Nie, Yujing Chen, Zixing Liu, Mengzhao Li, Chun Gong, Qiong Liu   +6 more
doaj   +1 more source

Mendelian randomization results of weighted median.

, 2023
Mendelian randomization results of weighted median.
Jianlin Zuo (13019001), Lanlan Chen (4860436), Haitao Li (305080), Hongqun Yang (11451091), Zhuangzhuang Ma (5220842), Chaofeng Yuan (17441259)   +5 more
core   +1 more source

Results of multivariable mendelian randomization (MVMR) analyses.

, 2023
Results of multivariable mendelian randomization (MVMR) analyses.
Maddalena Ardissino (9118004), Rohin K. Reddy (13716480), Fu Siong Ng (6547454), Kiran Haresh Kumar Patel, Greg J. Mellor, Maddalena Ardissino, Fu Siong Ng, Bilal Rayes (16799256), Bilal Rayes, Rohin K. Reddy, Greg J. Mellor (16799259), Kiran Haresh Kumar Patel (12971666)   +11 more
core   +1 more source

Graphical analysis for phenome-wide causal discovery in genotyped population-scale biobanks

Nature Communications, 2021
Mendelian randomization is a popular method to detect causal relationships between traits, but can be confounded by instances of horizontal pleiotropy. Here, the authors present a Mendelian randomization workflow which includes causal discovery analysis ...
David Amar, Nasa Sinnott-Armstrong, Euan A. Ashley, Manuel A. Rivas   +3 more
doaj   +1 more source

Mendelian randomization in family data [PDF]

BMC Proceedings, 2009
The phrase "mendelian randomization" has become associated with the use of genetic polymorphisms to uncover causal relationships between phenotypic variables. The statistical methods useful in mendelian randomization are known as instrumental variable techniques.
Morris, Nathan J, Gray-McGuire, Courtney, Stein, Catherine M   +2 more
openaire   +2 more sources

Study on the causal relationship between educational attainment and delirium: A two-sample Mendelian randomization study

Heliyon
This study aimed to investigate whether there is a causal relationship between educational attainment and delirium at the genetic level using the Mendelian randomization method, and provide new evidence for studies in this field.
Xianjie Wan, Hui Yu, Mingyi Yang, Weikun Hou, Jiale Xie, Ke Xu, Yujie Ma, Rui Ma, Fan Wang, Peng Xu   +9 more
doaj   +1 more source

Mendelian randomization coronary heart disease exposure pain outcome.

, 2023
Mendelian randomization coronary heart disease exposure pain outcome.
James A. Perry (10515389), Siobhan M. Schabrun (11929656), Susan G. Dorsey (11780093), Kathryn Ward (17174753), Evelina Mocci (374296), Seth A. Ament (9427801), Cynthia Renn (17174756), Angela Starkweather (10581244), Laura S. Stone (9392671)   +8 more
core   +1 more source

Results of Mendelian randomization analysis of PAS on intelligence.

, 2023
Results of Mendelian randomization analysis of PAS on intelligence.
Tianmin Zhu (2206318), Furong Zhang (5690462), Yushan Shi (16440272), Zhangmeng Xu (16726372), Guorong Qiu (16726375), Duoduo Yu (16726378), Guogang Dai (9228115)   +6 more
core   +1 more source