Correction: Endometrial senescence is mediated by interleukin 17 receptor B signaling [PDF]
Cell Communication and SignalingKeiko Kawamura +9 more
doaj +2 more sources
An essential role of interleukin-17 receptor signaling in the development of autoimmune glomerulonephritis. [PDF]
J Leukoc Biol, 2014 AbstractIn recent years, proinflammatory cytokines in the nephritic kidney appear to contribute to the pathogenesis of AGN. The complex inflammatory cytokine network that drives renal pathology is poorly understood. IL-17, the signature cytokine of Th17 cells, which promotes autoimmune pathology in a variety of settings, is beginning to be identified ...
Ramani K +5 more
europepmc +3 more sources
Differential regulation of interleukin-17 and interferon-y production in inflammatory bowel disease [PDF]
, 2010 PhDBackground and Aims. Interleukin (IL)-17 is now known to be involved in a number of chronic inflammatory disorders. However, the mechanisms regulating its production in inflammatory bowel disease (IBD) are still unclear. Methods.
Rovedatti, Laura
core +4 more sources
Applied Sciences, 2022 Background: Periodontitis (P) is a chronic inflammatory disease characterized by the destruction of periodontium support tissue generated by different immuno-inflammatory mechanisms, including the RANK/RANKL/OPG and the IL-23/IL-17 axis.
Ruth Rodríguez-Montaño +7 more
doaj +1 more source
Bioscience, Biotechnology, and Biochemistry, 2023 ABSTRACT This research is based on a Systematic Evolution of Ligands by EXponential enrichment, also referred to as in vitro selection against the extracellular domain of human interleukin-17 receptor A (IL-17RA). Pull-down assay via quantitative polymerase chain reaction and chemiluminescence detection showed that the cloned RNA with ...
Arifur Rahman Munshi +10 more
openaire +2 more sources
The parasitic helminth product ES-62 suppresses pathogenesis in collagen-induced arthritis by targeting the interleukin-17–producing cellular network at multiple sites [PDF]
, 2012 Among many survival strategies, parasitic worms secrete molecules to modulate host immune responses. One such product, ES-62, is protective in the collagen-induced arthritis (CIA) model of rheumatoid arthritis.
Pineda, Miguel +7 more
core +4 more sources
Interleukin-17 receptor antagonist reduces inflammatory response in experimental periodontitis
International Dental Journal, 2023 Aim or Purpose: Interleukin (IL)-17 is one of the inflammatory cytokines caused periodontitis and psoriasis. Psoriasis, a chronic inflammatory skin disease, treats with IL-17 receptor antagonist (brodalumab: BRD).
Dr Takenori Sato, Dr. Keisuke Handa
doaj +1 more source
Genetic association between interleukin-17 and susceptibility to rheumatoid arthritis
BMC Medical Genomics, 2023 Background The pathogenesis of rheumatoid arthritis (RA) is an immune imbalance, in which various inflammatory immune cells and pro-inflammatory factors are involved.
Rong Zhao +7 more
doaj +1 more source
Study on the Mechanism of Budesonide in the Treatment of IgA Nephropathy Based on Network Pharmacology [PDF]
Zhongguo quanke yixue, 2023 Background IgA nephropathy (IgAN) is the most common primary glomerulonephritis in China and worldwide, approximately 25%-30% of patients will progress to end-stage renal disease within 20 years after diagnosis.
ZHANG Kang, ZHAO Tingting, ZHANG Bo, GAO Mengqi, LI Yuxi, WANG Shaopeng, ZHAO Wenjing
doaj +1 more source
Effect of interleukin (IL)-35 on IL-17 expression and production by human CD4+ T cells [PDF]
PeerJ, 2017 Background Interleukin (IL)-17 produced by mainly T helper 17 (Th17) cells may play an important destructive role in chronic periodontitis (CP). Thus, anti-inflammatory cytokines, such as IL-35, might have a beneficial effect in periodontitis by ...
Kosuke Okada +12 more
doaj +2 more sources