β7 Integrin Inhibition Can Increase Intestinal Inflammation by Impairing Homing of CD25hiFoxP3+ Regulatory T Cells. [PDF]
, 2020 Background & aimsIntegrin α4β7 mediates lymphocyte trafficking to the gut and gut-associated lymphoid tissues, a process critical for recruitment of effector lymphocytes from the circulation to the gut mucosa in inflammatory bowel disease (IBD) and ...
Eckmann, Lars +5 more
core +1 more source
Interleukin-10 and soluble tumor necrosis factor receptor II are potential biomarkers of Plasmodium falciparum infections in pregnant women: a case-control study from Nanoro, Burkina Faso. [PDF]
, 2017 BACKGROUND: Diagnosis of malaria in pregnancy is problematic due to the low sensitivity of conventional diagnostic tests (rapid diagnostic test and microscopy), which is exacerbated due to low peripheral parasite densities, and lack of clinical symptoms.
Bradley, J +12 more
core +1 more source
Current review of genetically modified lactic acid bacteria for the prevention and treatment of colitis using murine models [PDF]
, 2015 Inflammatory Bowel Diseases (IBD) are disorders of the gastrointestinal tract characterized by recurrent inflammation that requires lifelong treatments.
Azevedo, Vasco +7 more
core +1 more source
eLife, 2017 Infants with defects in the interleukin 10 receptor (IL10R) develop very early onset inflammatory bowel disease. Whether IL10R regulates lamina propria macrophage function during infant development in mice and whether macrophage-intrinsic IL10R signaling
Naresh S Redhu +16 more
doaj +1 more source
Blood concentrations of endothelin, interleukins 6 and 10 in men with diabetes mellitus
Mìžnarodnij Endokrinologìčnij Žurnal, 2021 Background. Pathological activation of cytokines is one of the key links in the pathogenesis of diabetes mellitus (DM) and the development of its complications, in particular from the cardiovascular system.
E.V. Luchytskiy +4 more
doaj +1 more source
Mapping of the interleukin‐10/interleukin‐10 receptor combining site [PDF]
Protein Science, 1998 AbstractThe discontinuous interleukin‐10(IL‐10)/interleukin‐10 receptor (IL‐10R) combining site was mapped using sets of overlapping peptides derived from both binding partners bound to continuous cellulose membranes. Low affinity binding of single regions of the discontinuous contact sites on IL‐10 and IL‐10R could be identified due to (1) high ...
U, Reineke +3 more
openaire +2 more sources
Targeting self- and foreign antigens to dendritic cells via DC-ASGPR generates IL-10-producing suppressive CD4+ T cells [PDF]
, 2012 Dendritic cells (DCs) can initiate and shape host immune responses toward either immunity or tolerance by their effects on antigen-specific CD4(+) T cells.
Akira +66 more
core +2 more sources
Melatonin attenuates oxidative stress and modulates inflammatory response after experimental burn trauma [PDF]
, 2018 Introduction. Thermal injury activates an inflammatory response. Melatonin possesses anti-oxidant and anti-inflammatory properties. The objective of the present work was to study melatonin effects on the inflammatory response under ...
Atanasova, Milena +3 more
core +3 more sources
Cytokine profiling for Egyptian diabetic patients with nephropathy
Journal of Medicine in Scientific Research, 2022 Background Evidence suggests that poor glycemic control is significantly associated with the development of microvascular complications of diabetes such as nephropathy.
Samar M Samir +3 more
doaj +1 more source
Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2016 Background: Immune respons disturbance oftenly found in leprosy patient, mainly in various T cell subset and cytokine immune system arranger. Interleukin-10 produced by Th 2 cell, Th3 cell, monocyte, dendritic cell, eosinophil, mast cell, and ...
Eva Krishna Sutedja +2 more
doaj +1 more source