Results 11 to 20 of about 1,857,465 (364)
COVID-19: consider cytokine storm syndromes and immunosuppression
The Lancet, 2020 www.thelancet.com Published online March 13, 2020 https://doi.org/10.1016/S0140-6736(20)30628-0 1 Submissions should be made via our electronic submission system at http://ees.elsevier.com/ thelancet/ However, in hyperinflammation, immunosuppression is ...
Puja Mehta +5 more
semanticscholar +1 more source
An inflammatory cytokine signature predicts COVID-19 severity and survival
Nature Medicine, 2020 Several studies have revealed that the hyper-inflammatory response induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a major cause of disease severity and death.
D. D. Del Valle +31 more
semanticscholar +1 more source
, 2021 Periodontitis is a high prevalent disease into the clinical dentistry. Genetic variations in interleukins (IL) genes were associated with chronic periodontitis (CP) and were focus of several meta-analyses. This study aimed to assess the noteworthiness in
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medRxiv, 2020 Background: The dynamic changes of lymphocyte subsets and cytokines profiles of patients with novel coronavirus disease (COVID-19) and their correlation with the disease severity remain unclear.
Jing Liu +49 more
semanticscholar +1 more source
Cytokine release syndrome and associated neurotoxicity in cancer immunotherapy
Nature reviews. Immunology, 2021 A paradigm shift has recently occurred in the field of cancer therapeutics. Traditional anticancer agents, such as chemotherapy, radiotherapy and small-molecule drugs targeting specific signalling pathways, have been joined by cellular immunotherapies ...
E. Morris +3 more
semanticscholar +1 more source
The cytokine storm and COVID‐19
Journal of Medical Virology, 2020 Coronavirus disease 2019 (COVID‐19), which began in Wuhan, China, in December 2019, has caused a large global pandemic and poses a serious threat to public health.
B. Hu, Shaoying Huang, L. Yin
semanticscholar +1 more source
Cell, 2020 COVID-19 is characterized by excessive production of pro-inflammatory cytokines and acute lung damage associated with patient mortality. While multiple inflammatory cytokines are produced by innate immune cells during SARS-CoV-2 infection, we found that ...
Rajendra Karki +15 more
semanticscholar +2 more sources
The COVID-19 Cytokine Storm; What We Know So Far
Frontiers in Immunology, 2020 COVID-19 is a rapidly spreading global threat that has been declared as a pandemic by the WHO. COVID-19 is transmitted via droplets or direct contact and infects the respiratory tract resulting in pneumonia in most of the cases and acute respiratory ...
D. Ragab +4 more
semanticscholar +1 more source
Scientific Reports, 2017 The transcriptional activity of the glucocorticoid receptor (GR) is co-determined by its ability to recruit a vast and varying number of cofactors. We here identify Striatin-3 (STRN3) as a novel interaction partner of GR that interferes with GR’s ligand ...
Ioanna Petta +12 more
doaj +1 more source
Seminars in Immunopathology, 2017 Human coronaviruses (hCoVs) can be divided into low pathogenic and highly pathogenic coronaviruses. The low pathogenic CoVs infect the upper respiratory tract and cause mild, cold-like respiratory illness.
Rudragouda Channappanavar, S. Perlman
semanticscholar +1 more source