Results 11 to 20 of about 1,481,271 (307)

Engineering cytokines and cytokine circuits

Science, 2020
Learning to speak the secret language of immune cells could improve ...
Aileen W, Li, Wendell A, Lim
openaire   +3 more sources

Smoking in asthma is associated with elevated levels of corticosteroid resistant sputum cytokines—an exploratory study [PDF]

, 2013
<p>Background: Current cigarette smoking is associated with reduced acute responses to corticosteroids and worse clinical outcomes in stable chronic asthma. The mechanism by which current smoking promotes this altered behavior is currently unclear.
A McKay, A Sykes, B Pedersen, Carl de Wet, Charles McSharry, Christopher J. Weir, E Goleva, E Goleva, E Irusen, E Juniper, E Livingston, GJ Zijlstra, GW Chalmers, GW Chalmers, H Kerstjens, J Kam, J St-Laurent, JEM Tomlinson, M Althuis, M Broekema, M Spears, Marco Idzko, Mark Spears, MR Edwards, MR Miller, MR Stämpfli, NC Thomson, Neil C. Thomson, R Chaudhuri, R Chaudhuri, R Crapo, R Meijer, R Sher, Rekha Chaudhuri, S Holgate, SC Lazarus, SE Pedersen, SE Wenzel, WE Naugler, Z Qiu, Z Xing   +40 more
core   +8 more sources

Paracrine IL-2 Is Required for Optimal Type 2 Effector Cytokine Production [PDF]

, 2017
IL-2 is a pleiotropic cytokine that promotes the differentiation of Th cell subsets, including Th1, Th2, and Th9 cells, but it impairs the development of Th17 and T follicular helper cells.
Cherukur, Yesesri, Dent, Alexander L., Hummel, Sarah A., Janga, Sarath Chandra, Kaplan, Mark H., Khan, Ibrahim, Meuris, Brice, Olson, Matthew R., Ulrich, Benjamin J.   +8 more
core   +1 more source

Efficient lysis of rhabdomyosarcoma cells by cytokine-induced killer cells : implications for adoptive immunotherapy after allogeneic stem cell transplantation [PDF]

, 2010
Background: Rhabdomyosarcoma is the most common soft tissue sarcoma in childhood and has a poor prognosis. Here we assessed the capability of ex vivo expanded cytokine-induced killer cells to lyse both alveolar and embryonic rhabdomyosarcoma cell lines ...
Kuçi, Selim, Rettinger, Eva, Voß, Bernhard, Weber, Gerrit, Stais, Miriam, Kreyenberg, Hermann, Willasch, Andre Manfred, Kuçi, Zyrafete, Koscielniak, Ewa, Klöß, Stephan, Laer, Dorothee von, Klingebiel, Thomas, Bader, Peter   +12 more
core   +1 more source

Global landscape of mouse and human cytokine transcriptional regulation [PDF]

, 2018
Cytokines are cell-to-cell signaling proteins that play a central role in immune development, pathogen responses, and diseases. Cytokines are highly regulated at the transcriptional level by combinations of transcription factors (TFs) that recruit ...
Fuxman Bass, Juan Ignacio, Gan, Kok Ann, Imedio, Alvaro Dafonte, Martinez, Melissa, Mehta, Shivani, Pro, Sebastian Carrasco, Santoso, Clarissa Stephanie, Sereda, Rebecca, Sewell, Jared Allan   +8 more
core   +1 more source

Torsional stability of interference screws derived from bovine bone - a biomechanical study [PDF]

, 2010
Introduction: It has been proposed that individual genetic variation contributes to the course of severe infections and sepsis. Recent studies of single nucleotide polymorphisms (SNPs) within the endotoxin receptor and its signaling system showed an ...
Joscha Bauer, Turgay Efe, Silke Herdrich, Leo Gotzen, Bilal Farouk El-Zayat, Jan Schmitt, Nina Timmesfeld, Markus Dietmar Schofer, M Majewski, W Krudwig, A Weiler, JA Abate, LA Pinczewski, KD Shelbourne, G Milano, I Vuori, FH Fu, Y Ishibashi, G Laxdal, TR Duquin, R Seil, MS George, JS Suh, JO Drogset, L Macarini, F Pena, MH Baums, MP Hall, N Zheng, WL Adeyemo, R Rosito, DJ Beevers, OA Ilahi, LL Johnson, Y Kocabey, DK Park, MP Walsh, A Weiler, T Zantop, JJ Costi, J Nyland, BB Phillips, F Boccafoschi, C Hofmann, ST Pfuhler, DN Caborn, M Kurosaka, LS Matthews, PJ Novak, S Rupp, D Kohn, GB Maletis, S Piltz, IS Corry, LA Pinczewski, LS Matthews, PH Shen, T Zantop, K Tecklenburg, KW Wander, A Worth, OA Trentz, J Katz, P Hunt, BD Beynnon, DG Nagarkatti, CH Brown Jr   +66 more
core   +1 more source

Ex vivo innate immune cytokine signature of enhanced risk of relapsing brucellosis. [PDF]

, 2013
BackgroundBrucellosis, a zoonotic infection caused by one of the Gram-negative intracellular bacteria of the Brucella genus, is an ongoing public health problem in Perú.
Feldman, Kristyn E, Gilman, Robert H, Gotuzzo, Eduardo, Hoffmann, Alexander, Loriaux, Paul M, Saito, Mayuko, Siva, Tenaya, Tuero, Iskra, Villaverde, Homarh, Vinetz, Joseph M   +9 more
core   +3 more sources

Cytokine tuning of intestinal epithelial function [PDF]

, 2018
The intestine serves as both our largest single barrier to the external environment and the host of more immune cells than any other location in our bodies.
Andrews, Caroline, Durum, Scott K., McLean, Mairi H.   +2 more
core   +4 more sources

COVID-19 spike polypeptide vaccine reduces the pathogenesis and viral infection in a mouse model of SARS-CoV-2

Frontiers in Immunology, 2023
The SARS-CoV-2 coronavirus, which causes a respiratory disease called COVID-19, has been declared a pandemic by the World Health Organization (WHO) and is still ongoing. Vaccination is the most important strategy to end the pandemic.
Yasmin Hisham, Sun-Min Seo, Sinae Kim, Sinae Kim, Saerok Shim, Jihyeong Hwang, Eun-Seon Yoo, Na-Won Kim, Chang-Seon Song, Hyunjhung Jhun, Ho-Young Park, Youngmin Lee, Kyeong-Cheol Shin, Sun-Young Han, Je Kyung Seong, Je Kyung Seong, Yang-Kyu Choi, Soohyun Kim, Soohyun Kim   +18 more
doaj   +1 more source

Salivary cytokine panel indicative of non-small cell lung cancer. [PDF]

, 2018
Objective To develop a combinatorial panel of salivary cytokines that manifests the presence of non-small cell lung cancer (NSCLC) that will eventually improve prognosis by facilitating the early diagnosis and management of this common cancer. Methods We
Koizumi, Tomonobu, Shetty, Vivek, Yamaguchi, Masaki   +2 more
core   +3 more sources