Results 71 to 80 of about 3,516,666 (358)
TNF-α response in macrophages depends on clinical Legionella pneumophila isolates genotypes
, 2022 Legionnaires’ Disease (LD) is a severe pneumonia mainly caused in Europe by Legionella pneumophila serogroup 1 (Lp1). Sequence-based typing methods reveal that some sequence types (ST) are overrepresented in clinical samples such as ST1 and ST47 ...
Christophe Ginevra (6558530) +7 more
core +1 more source
Osteoarthritis and Cartilage OpenObjective: We previously identified extracellular vesicles (EVs) as a key source of TNF-α in the plasma of both knee osteoarthritis (OA) patients and healthy individuals.
Xin Zhang, Virginia Byers Kraus
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
TNF-α Stimulated iNOS mRNA and Transcription Factor Expression Dynamics.
, 2016 The system was simulated with LPS (control), TNF-α, and TNF-α with LPS as inputs. (A-D) show the transcription factors of iNOS under the three stimulatory conditions. STAT1 phosphorylated dimers remain at zero since there is no IFN-γ stimulation.
Taha Salim (2825270) +2 more
core +1 more source
A Novel TNF-α-Targeting Aptamer for TNF-α-Mediated Acute Lung Injury and Acute Liver Failure
Theranostics, 2019 Rationale: The TNF-α pathway plays as a double-edged sword that simultaneously regulates cell apoptosis and proliferation. The dysregulated TNF-α signaling can trigger cytokine storms that lead to profound cell death during the phase of acute tissue ...
Wei-Yun Lai +4 more
semanticscholar +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Electric foot-shock stress drives TNF-alpha production in the liver of IL-6-deficient mice [PDF]
, 2004 Objectives: Accumulating evidence has shown that interleukin-6 (IL-6) has pleiotropic effects on a variety of biological functions, including its antiapoptotic potential during liver injury.
Chida, Y, Motomura, Y, Kubo, C, Sudo, N
core
TNF-α infusion in AI results in tinnitus in normal-hearing wild-type and TNF-α KO mice.
, 2019 A. Behavioral evidence of tinnitus was assessed with gap detection. B. The ability to hear tones was assessed with PPI. TNF-α infusion resulted in impaired gap detection in both wild-type and TNF-α KO mice but did not alter their performances in PPI ...
Hao Luo (454719) +12 more
core +1 more source
THE ROLE OF IFN- γ AND TNF- α IN EXPERIMENTAL MASTITIS
The Iraqi Journal of Agricultural science, 2021 This study was design to characterize the immune response in experimentally Pseudomonas aeruginosa mastitis mice treated probiotic bifidocin and cazacin of Bifidobacterium spp. and Lactobacillus casei.
Touma & et al
doaj
TNF-α gene polymorphisms: association with age-related macular degeneration in Russian population [PDF]
International Journal of Ophthalmology, 2019 AIM: To study polymorphisms in promotor regions of tumor necrosis factor (TNF)-α TNF-863A/C (rs1800630), TNF-308A/G (rs1800629), and TNF-238A/G (rs361525) in patients with age-related macular degeneration (AMD) and associations of complex TNF-α genotypes
Valeriy Chernykh +5 more
doaj +1 more source