Results 81 to 90 of about 1,383,229 (318)

TNF-α and IFN-γ primed iNOS Gene Expression Dynamics.

, 2016
The model was simulated with TNF-α, IFN-γ, or both TNF-α /IFN-γ for 24 simulation hours to prime the system. The concentrations of iNOS transcription factors, iNOS mRNA, and iNOS protein were used as inputs to the system for an 8-hour addition simulation
Taha Salim (2825270), Elebeoba E. May (2825273), Cheryl L. Sershen (350195)   +2 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

TNF-α affects human cortical neural progenitor cell differentiation through the autocrine secretion of leukemia inhibitory factor. [PDF]

PLoS ONE, 2012
Proinflammatory cytokine tumor necrosis factor-alpha (TNF-α) is a crucial effector of immune responses in the brain that participates in the pathogenesis of several acute and chronic neurodegenerative disorders.
Xiqian Lan, Qiang Chen, Yongxiang Wang, Beibei Jia, Lijun Sun, Jialin Zheng, Hui Peng   +6 more
doaj   +1 more source

The Effect of Active Gambir (Uncaria gambir) Fraction on TNF-α Protein Expression and Lesion Size in Rats Induced Gastritis

Bioscientia Medicina : Journal of Biomedicine and Translational Research, 2018
Background: Gambir (Uncaria gambir) is empirically used to treat abdominal pain and vomittus caused by gastritis because of its anti-inflammatory effects, especially flavonoid. This study aims to determine the effect of active gambir fraction on TNF-α protein expression and wound size in white rats gastritis model. Methods: The research method ...
Ni Wayan Lisa Suasti, Lunsi Oktafitria, Ellya Aidia, Rahmad Dhani   +3 more
openaire   +1 more source

Profil TNF-α sesaat setelah melakukan senam zumba

Jurnal e-Biomedik, 2016
Abstract: Tumor Necrosis Factor-alpha (TNF-α) is one type of pro inflammatory cytokines produced by macrophages and T cell as response to acute inflammation and trauma. Exercise can be the cause of the physical stress that can lead to muscle and joints damage.
Ratulangi, Maria R. J., Polii, Hedison, Wungouw, Herlina I. S.   +2 more
openaire   +3 more sources

TNF-α-mediated activation of HIV-1 LTR in monocytoid cells by mycobacteria [PDF]

FEMS Immunology & Medical Microbiology, 2001
Mycobacterial infection occurs commonly in patients with acquired immune deficiency syndrome. Incubation of monocytoid cell line U937 cells, which was cotransfected HIV-1 long terminal repeat sequence (LTR) chloramphenicol acetyltransferase (CAT) plasmid and Tat expression plasmid, with Mycobacterium smegmatis, Mycobacterium avium, Mycobacterium bovis ...
H, Kitaura, N, Ohara, K, Kobayashi, T, Yamada   +3 more
openaire   +2 more sources

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Hyperuricemia and Pro Inflammatory Cytokine (IL-1β, IL-6, and TNF-α)

Indonesian Journal of Rheumatology, 2018
Background. Rugerio et al 2006 reported that there were a positive correlation between the level of hyperuricemia and the level of IL-1β, IL-6, and TNF-α pro infl ammatory cytokines value. On the other hand, Choi et al reported a negative correlation between hyperuricemia and the level of pro infl ammatory cytokine in the late phase of hyperuricemia.
Suyanto Hadi, D Sudarsono, Bantar Suntoko   +2 more
openaire   +1 more source

UTL-5g Lowers Levels of TGF-β and TNF-α Elevated by Lung Irradiation and Does Not Affect Tumor-response to Irradiation

American Journal of Biomedical Sciences, 2014
UTL-5g is a small-molecule TNF- inhibitor having chemoprotective and liver radioprotective effects. We investigated the effects of UTL-5g on lung irradiated mice and whether UTL-5g affects tumor responses to radiotherapy. C57BL/6 mice were individually treated with UTL-5g at 15, 30, and 60 mg/kg and amifostine (200 mg/kg) by i.p.
Stephen Brown, Frederick Valeriote, Ben Chen, Kevin Bobbitt, Joseph Media, Halina Pietraszkiewicz, Jiajiu Shaw   +6 more
openaire   +1 more source

TNF-α and adiponectin.

, 2016
Histograms of A) tumor necrosis factor alpha (TNF-α) (pg/ml) and B) adiponectin (ng/ml) in plasma of lean Zucker rats (white), obese Zucker rats that received water (black) and obese Zucker rats that received 750 mg/kg/day of pepsin egg white hydrolysate
C. González (2949234), J. A. Uranga (3176838), R. López-Fandiño (3176835), V. López-Miranda (3176841), M. Miguel (3176844), M. Garcés-Rimón (3176847)   +5 more
core   +1 more source