Results 81 to 90 of about 3,516,666 (358)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
TNF-α Expression Test (TET) for endotoxin detection.
, 2016 a). The TET was performed to detect endotoxin content in all GBMs upon exposure of HMDM to 25 and 50 μg/ml for 24 h. The differences in TNF-α expression in the presence and absence of polymyxin B sulfate (Poly-B) (10 μM) provided evidence of the presence
Peter Wick (435597) +8 more
core +1 more source
Disease progression and protection by anti-TNF-α Ab treatment.
, 2023 (A) IFN-α/β/γR knockout (KO) mice (8–10 weeks old) were infected intraperitoneally with 2 × 106 focus-forming units (FFU) of DENV-3 P12/08 and sacrificed at Days 2, 3, and 4 post-infection (p.i.).
Mohamad Al Kadi (11987393) +14 more
core +1 more source
Journal of Biomedical Science, 2009 Atorvastatin has been shown to reduce resistin expression in macrophages after pro-inflammatory stimulation. However, the mechanism of reducing resistin expression by atorvastatin is not known. Therefore, we sought to investigate the molecular mechanisms
Chua Su-Kiat +3 more
doaj +1 more source
Immunology Letters, 2017 Programmed cell death protein 1 (PD-1) acts on PD-1 ligands (PD-L1 and PD-L2) to suppress activation of cytotoxic T lymphocytes. Interleukin-17 (IL-17) and tumor necrosis factor-α (TNF-α) are co-expressed by T helper 17 (TH17) cells in many tumors.
Xun Wang +6 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
A Case with Anti TNF- α Induced Bullous Pemhigoid
The Turkish Journal of Gastroenterology, 2010 Tumor necrosis factor-alpha (TNF-α) plays a crucial role in the development of autoimmune diseases, and anti-TNF-α agents are used in the treatment of this group of diseases.
Özlem Altındağ +2 more
doaj
CNS Demyelination with TNF-α Blockers
Current Neurology and Neuroscience Reports, 2017 Tumor necrosis factor–α (TNF-α) blockers are a popular therapeutic choice in a number of inflammatory diseases. Thus far, five TNF- α blockers have been approved for clinical use (etanercept, infliximab, adalimumab, golimumab. and certolizumab).
E. Kemanetzoglou, E. Andreadou
semanticscholar +1 more source
Jurnal Kedokteran Brawijaya, 2016 Preeklampsia ditandai dengan adanya hipertensi dan proteinuria pada usia kehamilan lebih dari 20 minggu. Preeklampsia diderita oleh 3%-8% wanita hamil dan menjadi penyebab utama kematian pada kehamilan. Tumor Necrosis Factor-α(TNF-α) diduga memiliki peranan penting dalam menimbulkan terjadinya preeklampsia.
Syahroni Yudistian Agmar +2 more
openaire +1 more source
TNF-α-mediated activation of HIV-1 LTR in monocytoid cells by mycobacteria [PDF]
FEMS Immunology & Medical Microbiology, 2001 Mycobacterial infection occurs commonly in patients with acquired immune deficiency syndrome. Incubation of monocytoid cell line U937 cells, which was cotransfected HIV-1 long terminal repeat sequence (LTR) chloramphenicol acetyltransferase (CAT) plasmid and Tat expression plasmid, with Mycobacterium smegmatis, Mycobacterium avium, Mycobacterium bovis ...
H, Kitaura +3 more
openaire +2 more sources