Results 81 to 90 of about 820,645 (209)

VCAM1 modulation on endothelial cells – implications for vasculopathy in sickle cell anemia [PDF]

, 2019
Sickle cell anemia (SCA) is a highly heterogeneous and multifactorial-like monogenic disease that arises from homozygosity for the c.20A>T mutation in the HBB gene.
Coelho, Andreia, Faustino, Paula, Lavinha, João, Silva, Marisa, Vargas, Sofia   +4 more
core  

Familial Aggregation of High Tumor Necrosis Factor Alpha Levels in Systemic Lupus Erythematosus

Clinical and Developmental Immunology, 2013
Systemic lupus erythematosus (SLE) patients frequently have high circulating tumor necrosis factor alpha (TNF-α) levels. We explored circulating TNF-α levels in SLE families to determine whether high levels of TNF-α were clustered in a heritable pattern.
Dorothy Mangale, Silvia N. Kariuki, Beverly S. Chrabot, Marissa Kumabe, Jennifer A. Kelly, John B. Harley, Judith A. James, Kathy L. Sivils, Timothy B. Niewold   +8 more
doaj   +1 more source

THE INFLUENCE OF PEPAYA LEAF STEW (CARICA PAPAYA) ON PROSTAGLANDIN (PGF2 α) AND TNF-α LEVELS IN DISMENOREA PATIENTS

Jurnal Kesehatan, 2023
Analysis:The prevalence of dysmenorrhoea in Indonesia is quite high at 64.25%. Several factors are known as a factor in the occurrence of dysmenorrhoea among others is the increased synthesis of Prostaglandins (PGF2α) and Cytokines (TNFαα) as mediators that play an important role besides PGF2α in the inflammatory process.Method:The purpose of this ...
Nisa, Setia, Maifita, Yesi
openaire   +1 more source

KORELASI KADAR CRP, TNF-α DAN BONE MINERAL DENSITY DENGAN CARBOXYTERMINAL CROSSLINKED TELOPEPTIDE TYPE I OF COLLAGEN DI PENDERITA ARTRITIS REUMATOID

INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY, 2018
Rheumatoid Arthritis (RA) is a systemic autoimmune disease accompanied by decreasing bone mass density and ultimately leads toosteoporosis. The cause of decreased bone mass density is still unknown, but the inflammation has been suspected as an important factor.The correlation between the severity of inflammation with the decrease in bone mass density ...
Kusworini Handono, BP Putra Suryana, Sulistyorini Sulistyorini   +2 more
openaire   +2 more sources

Moderate Concentrations of TNF- α Induce BMP-2 Expression in Endothelial Cells [PDF]

, 2016
Tumor necrosis factor-alpha (TNF-α) is best-known as a potent pro-inflammatory cytokine involved in many cardiovascular diseases. During vascular calcification, TNF-α has been reported topromote osteogenic differentiation of human vascular smooth muscle ...
Hidajat Sujuti, Nur Permatasari, Oski Illiandri, Setyawati Soeharto   +3 more
core   +1 more source

TNF-α enhances Th9 cell differentiation and antitumor immunity via TNFR2-dependent pathways

Journal for ImmunoTherapy of Cancer, 2019
Tumor specific Th9 cells are potential effector cells for adoptive therapy of human cancers. TNF family members OX40L, TL1A and GITRL have been shown to promote the induction of Th9 cells and antitumor immunity.
Yuxue Jiang, Jintong Chen, Enguang Bi, Yinghua Zhao, Tianxue Qin, Yiming Wang, Alison Wang, Sujun Gao, Qing Yi, Siqing Wang   +9 more
doaj   +1 more source

Ekstrak Metanol Daun Kelor Menurunkan Kadar TNF-α dan IL-6 Serum, serta MDA Kolon Tikus yang Diinduksi DMBA

Jurnal Kedokteran Brawijaya, 2016
Ekstrak daun kelor (Moringa oleifera) dapat berfungsi sebagai anti oksidan, anti radang, dan anti kanker.TNF-α dan IL-6 merupakan sitokin proinflamasi yang berperan penting pada patogenesis kanker, sedangkan pada jaringan kanker sering ditemukan peningkatan kadar MDA.
Tinny Endang H, Dian Sukma H
openaire   +1 more source

The ability of earthworm Lumbricus rubellus extract in slowing down the activation of NFkB and TNF-α in lipopolysaccharide-induced Rattus norvegicus

Bali Medical Journal, 2019
Background: Earthworm (L. rubellus) contains many compounds such as Lumbricin I, G-90 glycoprotein, and polyphenols as antimicrobial, antioxidant, and hepatoprotective toward bacterial infections. Tumor necrosis factor (TNF-α) has been identified as a mediator for necrosis tumor inside animal serum treated by lipopolysaccharide (LPS).
Neiny Prisy Foekh, I Dewa Made Sukrama, Anak Agung Wiradewi Lestari   +2 more
openaire   +1 more source

TNF-α reduces the level ofStaphylococcus epidermidisinternalization by bovine endothelial cells [PDF]

FEMS Microbiology Letters, 2009
Staphylococcus epidermidis is an environmental opportunistic pathogen associated with bovine intramammary infections. In bacterial infections, the endothelial tissue plays an important role during inflammation and it is the target of proinflammatory cytokines such as tumor necrosis factor alpha (TNF-alpha).
Javier, Oviedo-Boyso, Alejandro, Bravo-Patiño, Marcos, Cajero-Juárez, Juan J, Valdez-Alarcón, Víctor M, Baizabal-Aguirre   +4 more
openaire   +2 more sources

Insulin attenuates TNFα-induced hemopexin mRNA: An anti-inflammatory action of insulin in rat H4IIE hepatoma cells

Biochemistry and Biophysics Reports, 2017
Proinflammatory cytokines, including TNF-α and IL-6, can contribute to insulin resistance. Conversely, insulin has some actions that can be considered anti-inflammatory.
J. Lee Franklin, William L. Bennett, Joseph L. Messina   +2 more
doaj   +1 more source