Results 91 to 100 of about 820,645 (209)

The Effect of Active Gambir (Uncaria gambir) Fraction on TNF-α Protein Expression and Lesion Size in Rats Induced Gastritis

open access: yesBioscientia Medicina : Journal of Biomedicine and Translational Research, 2018
Background: Gambir (Uncaria gambir) is empirically used to treat abdominal pain and vomittus caused by gastritis because of its anti-inflammatory effects, especially flavonoid. This study aims to determine the effect of active gambir fraction on TNF-α protein expression and wound size in white rats gastritis model. Methods: The research method ...
Ni Wayan Lisa Suasti   +3 more
openaire   +1 more source

The anti-sepsis activity of the components of Huanglian Jiedu Decoction with high lipid A-binding affinity [PDF]

open access: yes, 2017
Huanglian Jiedu Decoction (HJD), one of the classic recipes for relieving toxicity and fever, is a common method for treating sepsis in China. However, the effective components of HJD have not yet been identified.
Chen, Guirong   +7 more
core   +2 more sources

Exhaled Volatile Organic Compounds during Inflammation Induced by TNF-α in Ventilated Rats

open access: yesMetabolites, 2020
Systemic inflammation alters the composition of exhaled breath, possibly helping clinicians diagnose conditions such as sepsis. We therefore evaluated changes in exhaled breath of rats given tumor necrosis factor-alpha (TNF-α). Thirty male Sprague-Dawley
Frederic W. Albrecht   +9 more
doaj   +1 more source

UTL-5g Lowers Levels of TGF-β and TNF-α Elevated by Lung Irradiation and Does Not Affect Tumor-response to Irradiation

open access: yesAmerican Journal of Biomedical Sciences, 2014
UTL-5g is a small-molecule TNF- inhibitor having chemoprotective and liver radioprotective effects. We investigated the effects of UTL-5g on lung irradiated mice and whether UTL-5g affects tumor responses to radiotherapy. C57BL/6 mice were individually treated with UTL-5g at 15, 30, and 60 mg/kg and amifostine (200 mg/kg) by i.p.
Stephen Brown   +6 more
openaire   +1 more source

Immunomodulatory Effect of Toll-Like Receptor-3 Ligand Poly I:C on Cortical Spreading Depression [PDF]

open access: yes, 2009
The release of inflammatory mediators following cortical spreading depression (CSD) is suggested to play a role in pathophysiology of CSD-related neurological disorders.
Aghabarari, A.   +8 more
core   +2 more sources

TNF-α -308 A allele is associated with an increased risk of distant metastasis in rectal cancer patients from Southwestern China.

open access: yesPLoS ONE, 2017
Tumor necrosis factor-α (TNF-α), an important factor in systematic inflammation, is reportedly involved in several cancer types. The TNF-α -308 G>A (rs1800629) polymorphism in the promoter region influences TNF-α production. The association between TNF-α
Zhen Li   +11 more
doaj   +1 more source

High Dose (5mg) Daily Folic Acid Supplement in Healthy Brazilian Volunteers Increases Mononuclear TNF-α Expression and Reduces NK Cell Number and Activity

open access: yesBlood, 2015
Abstract Background In Brazil, wheat and corn flour is fortified with 150 µg of folic acid (FA), the synthetic form of folate. Individuals with increased cell duplication, including pregnant women and patients with hemolytic anemia need increased amounts of folate.
Juliano Bertinato   +7 more
openaire   +1 more source

The circulating proteinase inhibitor α-1 antitrypsin regulates neutrophil degranulation and autoimmunity. [PDF]

open access: yes, 2014
Pathological inflammation and autoimmune disease frequently involve elevated neutrophil activity in the absence of infectious agents. Tumor necrosis factor-α (TNF-α) contributes to many of the problems associated with autoimmune diseases. We investigated
Bergin, David A   +6 more
core   +1 more source

Indexing TNF-α gene expression using a gene-targeted reporter cell line [PDF]

open access: yes, 2009
Background Current cell-based drug screening technologies utilize randomly integrated reporter genes to index transcriptional activity of an endogenous gene of interest.
Ziying Yan   +3 more
core   +2 more sources

Profil Tumor Necrosis Factor (Tnf-α) Berdasarkan Indeks Massa Tubuh (Imt) Pada Mahasiswa Fakultas Kedokteran Unsrat Angkatan 2014 [PDF]

open access: yes, 2015
: Tumor Necrosis Factor alpha (TNF-α) is one of the pleiotrophic cytokines that plays a role in the inflammatory process, initiates and activates polymorphonuclears (PMNs), therefore the PMNs can reach the infection site.
Marunduh, S. R. (Sylvia)   +2 more
core  

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