Results 91 to 100 of about 1,383,229 (318)
TNF-α expression and age in skin punch biopsies of healthy controls and PD patients.
, 2022 Age is not correlated with altered TNF-α gene expression in the skin punch biopsy samples obtained from the lateral lower leg of healthy controls (a, b) and PD patients (c, d). Abbreviations: PD = Parkinson’s disease, TNF-α = tumor necrosis factor-alpha.
Anastasia Kuzkina (14019707) +5 more
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FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
ヒト歯肉上皮細胞のInterleukin-8産生に対するtumor necrosis factor -αの影響 [PDF]
大阪歯科大学Osaka Dental University博士（歯学）Tumor necrosis factor (TNF)-α is an inflammatory mediator that is released during the early stages of the inflammatory response and plays an important role in the development of periodontitis.
鄭, 峰, Zheng, Feng, テイ, ホウ
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, 2022 Tumour Necrosis Factor-alpha (TNF-α) is one of the main drivers of inflammatory bowel disease (IBD). Regulating the actions of this pro-inflammatory cytokine through selective antagonism using an anti-TNF-α monoclonal antibody (mAb) provides effective
Owen Rees Griffiths (13040982)
core +1 more source
FEBS Open Bio, EarlyView.In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
Familial Aggregation of High Tumor Necrosis Factor Alpha Levels in Systemic Lupus Erythematosus
Clinical and Developmental Immunology, 2013 Systemic lupus erythematosus (SLE) patients frequently have high circulating tumor necrosis factor alpha (TNF-α) levels. We explored circulating TNF-α levels in SLE families to determine whether high levels of TNF-α were clustered in a heritable pattern.
Dorothy Mangale +8 more
doaj +1 more source
TNF-α levels in psychosis group.
, 2019 Agitated psychosis patients had significantly higher serum levels of TNF-α compared to non-agitated psychosis patients (21.71 ± 27.00 vs 12.84 ± 18.15 pg/ml). data are expressed as median ± 95% confidence interval. **p = 0.027.
Arne Vaaler (525065) +3 more
core +1 more source
FEBS Open Bio, EarlyView.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Sarcoidosis: is there a role for anti-TNF-α?
Revista Portuguesa de Pneumologia, 2007 AbstractIn severe cases of sarcoidosis treatment can be very difficult. The common treatment strategies might be failing. Tumour necrosis factor (TNF) α therapy is approved in rheumatoid arthritis, M. Crohn, psoriasis and ankylosing spondylitis. In sarcoidosis more recently a phase 2, multicenter, randomized, double-blind, placebo-controlled study was ...
openaire +3 more sources
Jurnal Kedokteran Brawijaya, 2016 Preeklampsia ditandai dengan adanya hipertensi dan proteinuria pada usia kehamilan lebih dari 20 minggu. Preeklampsia diderita oleh 3%-8% wanita hamil dan menjadi penyebab utama kematian pada kehamilan. Tumor Necrosis Factor-α(TNF-α) diduga memiliki peranan penting dalam menimbulkan terjadinya preeklampsia.
Syahroni Yudistian Agmar +2 more
openaire +1 more source