Results 91 to 100 of about 14,254 (195)

Immunotherapy strategies and pharmaceutical care practice on a long-term surviving patient with advanced gastric cancer and mismatch repair deficient [PDF]

open access: yes
To analyze the treatment strategy for a 78-year-old female patient with mismatch repair deficient (dMMR) gastric cancer who achieved long-term survival.
Jinyin LI   +5 more
core   +1 more source

香菇多糖抗胃癌机制研究

open access: yesZhongguo shiyan zhenduanxue, 2011
胃癌是我国常见的恶性肿瘤,全世界35%胃癌发生在中国,年发病30多万,年胃癌死亡超过26万。免疫治疗可通过直接抑制肿瘤细胞及增强机体免疫功能等作用治疗肿瘤 ...
冯燕, 全吉钟, 王冬旭, 吕晓鹏
doaj  

CIK治疗前后肿瘤患者外周血CD4+ CD25+调节型T细胞变化研究

open access: yesZhongguo shiyan zhenduanxue, 2011
目的探讨细胞因子诱导的杀伤(Cytokine-induced killer cells,CIK)细胞治疗后肿瘤患者的免疫功能改变。方法采用流式细胞术检测28例肿瘤患者经CIK细胞治疗前后外周血CD4+CD25+T细胞比例。结果肿瘤患者CD4+CD25+T细胞比例明显高于对照组 ...
李敏   +11 more
doaj  

Detection of PD-L1 protein in circulating tumor cells of Non Small Cell Lung Cancer [PDF]

open access: yes, 2017
背景现状及研究的目的意义 目前,肺癌位居全世界死亡率和发病率很高的恶性肿瘤之一。按病理组织学,分为小细胞肺癌(smallcelllungcancer,SCLC)和非小细胞肺癌(nonsmallcelllungcancer,NSCLC),其中大约80%是NSCLC。由于NSCLC早期的临床症状和体征不明显,大概2/3的NSCLC患者在确诊时就已经失去手术根治的机会。由于传统的化疗药物和放疗治疗不能获得很好的疗效,NSCLC自诊断之后的5年生存率只有10%-15 ...
吴晓婷
core  

Analysis of pathological remission degree and influencing factors of radical surgery after neoadjuvant immunotherapy combined with chemotherapy in patients with locally advanced esophageal squamous cell carcinoma [PDF]

open access: yes
Background and purpose: Radical surgery after neoadjuvant immunotherapy combined with chemotherapy (nICT) in patients with locally advanced esophageal squamous cell carcinoma (LAESCC) has good efficacy and safety, and it can improve the patients ...
LIAO Ziyi, PENG Yang, ZENG Beilei, MA Yingying, ZENG Li, GAN Kelun, MA Daiyuan
core   +1 more source

An exploratory study on the perioperative treatment of locally advanced gastric cancer with combination of penpulimab, anlotinib and chemotherapy [PDF]

open access: yes
Background and purpose: There is a consensus within the medical community regarding the perioperative treatment of locally advanced gastric cancer (LAGC), yet the selection of an efficient and safe treatment strategy remains a contentious issue. Previous
LIU Shuai, ZHANG Kai, ZHANG Xiaoqing, LUAN Wei
core   +1 more source

Progress of Targeted Therapy and Immunotherapy for Gastric Cancer [PDF]

open access: yes
Gastric cancer (GC) is a common malignant tumor of the digestive tract in China. It is characterized by high morbidity, mortality, and proportion of patients in advanced stages.
PAN Hongming, ZHENG Yu
core   +1 more source

女性生殖道湿疣患者电灼治疗后免疫状态的变化

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 1999
目的: 比较电灼治疗前后女性生殖道湿疣的免疫状态变化, 了解患者其免疫功能在湿疣发展中的作用。方法: 采用流式细胞技术及比浊法对 45例生殖道湿疣及 30例正常妇女的血淋巴细胞亚群及血清免疫球蛋白和补体进行检测。结 果: 湿疣者 CD3、CD4、CD4/CD8 及 IgA、C3水平低于正常对照组, 治疗后无复发者 12 例的 5 项指标比治疗前升高, 而复发者 33 例则无变化。结论: 免疫功能在湿疣的发生发展中起关键作用,电灼等治疗可刺激机体的免疫功能。
doaj  

肾移植术后不同免疫抑制方案五年随访观察(附256例报告)

open access: yesZhongguo shiyan zhenduanxue, 2012
随着新型免疫抑制剂的出现,肾移植的人/肾存活率已得到很大的提高,已成为治疗终末期肾功能衰竭的有效手段,然而,这些免疫抑制剂的治疗窗很窄,移植医生应根据不同的个体施行个体化免疫抑制治疗方案,以期达到科学合理的用药,提高患者肾移植术后的生活质量和存活率。现将我院2005年6月至2006年12月256例肾移植患者的五年用药随访情况报告如下。
王钢   +5 more
doaj  

铁死亡调控肝细胞癌及其肿瘤免疫研究进展

open access: yes浙江大学学报. 医学版
铁死亡是一种依赖铁代谢失衡并以脂质过氧化为特征的调控性细胞死亡形式,在多种病理过程中发挥关键作用。研究表明,铁死亡的发生与肝细胞癌(HCC)的进展密切相关。铁死亡参与调控HCC的脂质代谢、铁离子稳态、线粒体代谢和氧化还原过程,在HCC肿瘤免疫中发挥着关键作用。铁死亡通过调节免疫微环境中不同细胞的表型和功能影响肿瘤的免疫逃逸和进展;铁死亡诱导的脂质过氧化物和氧化应激能促进M1型巨噬细胞的极化,增强肿瘤的促炎反应,同时抑制髓源性抑制细胞和调节性T细胞等免疫抑制细胞的功能,从而破坏免疫抑制 ...
莫 宇倩, 邹 志霖, 陈 二宝
doaj   +1 more source

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