Measles， rubella， and mumps antibody seroprevalence among the children aged 18 years and younger in Karamay City， Xinjiang Uygur Autonomous Region [PDF]
ObjectiveTo understand the measles, rubella, and mumps antibody seroprevalence among the children aged 18 years and younger in Karamay City, and to evaluate the effectiveness of vaccination.MethodsA stratified whole cluster random sampling method was ...
LI Xia +5 more
core +1 more source
Epidemiological and clinical characteristics of surveillance cases in a sentinel hospital for pertussis in Jiangxi Province in 2019 [PDF]
ObjectiveTo analyze the epidemiological and clinical characteristics of surveillance cases in a sentinel hospital for pertussis in Jiangxi Province in 2019, and to provide corresponding references for the prevention and control of pertussis.MethodsCase ...
GUO Shicheng +5 more
core +1 more source
Immunogenicity and safety of an E. coli-produced bivalent humanpapillomavirus (type 16 and 18) vaccine in preadolescent girls of 9-17 years [PDF]
, 2017 目的：评价重组人乳头瘤病毒16/18型双价疫苗（大肠杆菌）在9-17岁女性人群中的免疫原性和安全性。 方法：研究对象经知情同意、入选或排除标准筛查合格后进入研究。本研究采用开放性试验设计，9-14岁者被随机分配至0/6月2针免疫程序组或0/1/6月3针免疫程序组，15-26岁者全部被分配3针免疫程序组。研究对象按照规定免疫程序接种研究用疫苗。每针接种后记录1个月内的不良反应/事件。采集免前、6月、7月血清标本，测定IgG抗体、中和抗体以作免疫原性评价。 结果 ...
何文刚
core
La traduzione specializzata all’opera per una piccola impresa in espansione: la mia esperienza di internazionalizzazione in cinese di Bioretics© S.r.l. [PDF]
, 2023 Global markets are currently immersed in two all-encompassing and unstoppable processes: internationalization and globalization. While the former pushes companies to look beyond the borders of their country of origin to forge relationships with foreign ...
Tamburini, Matteo
core
Suspected adverse events following immunization associated with seperate/combined administration of 13-valent pneumococcal polysaccharide conjugate vaccine and oral pentavalent human rotavirus live attenuated vaccine in age-eligible children in a district of Shanghai [PDF]
ObjectiveTo analyze the safety of simultaneous vaccination of 13-valent pneumococcal conjugate vaccine (PCV13) and oral pentavalent human rotavirus live attenuated vaccine (RV5) in age-eligible children in Changning District, Shanghai.MethodsAdverse ...
CHEN Jinyan, PANG Hong
core +1 more source
Persistence of antibodies induced by natural hepatitis E virus infection with or without hepatitis E vaccine boosting and the seroprotective antibody level of hepatitis E [PDF]
, 2017 自然感染获得的免疫力对于预防HEV的新发感染发挥着重要的作用，但自然感染获得的HEV抗体的衰减规律和持续时间尚不清楚。本研究基于戊型肝炎疫苗Ⅲ期临床试验及其延续性监测中所采集的免后5.5年内的系列血清抗-HEVIgG数据，将其分成三个数据集进行免疫持久性分析，数据集A为对照组基线HEVIgG阳性人群，7m及之后至少一个时间点有抗-HEVIgG定量检测结果，共纳入2242人；数据集B为对照组7m内HEV新发感染人群，7m之后至少一个时间点有抗-HEVIgG定量检测结果，共纳入60人 ...
苏迎盈
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浙江大学学报. 医学版副黏病毒是一类重要的呼吸道病原体，在儿童感染性疾病中具有重要临床意义。其感染过程中可诱导多种形式的程序性细胞死亡（PCD），这些PCD形式在病毒复制、传播及宿主免疫应答中发挥关键作用，显著影响病毒的生命周期及疾病进展。一方面，PCD通过清除被感染细胞有助于限制病毒扩散并激活宿主免疫应答，从而增强抗病毒防御能力；另一方面，过度或异常的细胞死亡可能导致组织损伤和免疫紊乱，为病毒复制提供有利环境，进而加重病情。如细胞凋亡通过外源性与内源性通路参与感染控制，同时亦可能被病毒操控以增强其扩散能力 ...
刘 叶 +3 more
doaj +1 more source
The protective effect of acellular pertussis vaccine in children ≤10 years of age in Nanshan district, Shenzhen city: a case-control study [PDF]
ObjectiveTo evaluate the protective effectiveness (VE) of acellular pertussis vaccine (aPV) in children ≤10 years of age in Nanshan district, Shenzhen city, Guangdong province, and to provide a reference for optimizing pertussis immunization strategies ...
Jianhui YUAN +5 more
core +1 more source
, 2019 疫苗是公共卫生领域最大的成就之一,疫苗的接种是预防和控制传染病最经济有效的手段。目前,全球共批准预防性疫苗77种,用于预防41种疾病。全球疫苗市场总额近年来稳步增长,2017年达到277亿美元。国际疫苗四大巨头葛兰素史克、默沙东、辉瑞和赛诺菲巴斯德在不断的并购整合下,占据全球90%的销售额。我国疫苗市场发展迅速,2017年市场总额达224亿元,且疫苗品种不断丰富。但我国疫苗产业水平与发达国家仍存在明显差距。需加大疫苗研究投入、合理布局、完善监管制度以推动技术创新 ...
于振行 +5 more
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野生动物学报, 2017 采用牛口蹄疫疫苗对梅花鹿进行不同时段不同剂量免疫注射,定期进行抗体检测,以了解和掌握梅花鹿注射疫苗后鹿只免疫抗体的产生和消长规律,进而探明梅花鹿口蹄疫免疫的最佳程序和方法,确定梅花鹿口蹄疫的免疫计划,为广大梅花鹿饲养者进一步做好梅花鹿口蹄疫疫病的防控工作、提高梅花鹿群体保护率提供依据和方法。
吕见涛 陈法荣 杨玉澜 江海玲 李苗德 方朝柱 吕 濛
doaj