[Research Progress on the Regulatory Mechanism of Respiratory Microbiota in the Comorbidity of Chronic Obstructive Pulmonary Disease and Lung Cancer]. [PDF]
Zhongguo Fei Ai Za ZhiZhang Y, Zhang T, Wang H.
europepmc +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban目的在急诊重症监护室（EICU）脓毒症患者中，探讨宏基因高通量测序技术（mNGS）的临床应用价值及其指导精准抗感染治疗的意义，并分析影响mNGS阳性检出率及患者预后的关键因素。方法回顾性分析2020年11月至2024年10月在中山大学孙逸仙纪念医院EICU收治的524例脓毒症患者临床资料，比较mNGS与传统培养在阳性检出率、病原体构成及一致性方面的差异；评估感染部位、基础疾病及免疫状态对mNGS阳性检出率的影响，并分析根据mNGS结果调整抗感染方案对患者预后的作用。结果mNGS阳性检出率显著高于传统培养（
杜静, 林帆荣, 张洁, 杨正飞
doaj
[Extracellular matrix materials and tissue regeneration and repair]. [PDF]
Zhongguo Xiu Fu Chong Jian Wai Ke Za ZhiZhao L, Xie H.
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[cGAS-STING agonist cGAMP enhances natural killer cell-mediated cytotoxicity against gastric cancer cells]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoWang Q +6 more
europepmc +1 more source
ARF鸟苷酸交换因子BIGs对高尔基体相关的囊泡转运的调控作用
Zhongshan Daxue xuebao. Yixue kexue ban, 2012 【目的】 探讨ARF鸟苷酸交换因子BIG1和BIG2在高尔基体相关囊泡转运方面的功能。【方法】 利用脂质体将 siRNA干扰序列转入细胞中,western blotting方法检测转染效率; 利用细胞免疫荧光染色方法检测Hela细胞中 BIGs蛋白水平的表达分布; 采用Alexa568标记的转铁蛋白孵育Hela细胞,检测转铁蛋白相关的内吞体循环;利用脂质体转染VSVG-YFP病毒质粒,检测新生蛋白经从内质网经高尔基体转运至胞膜的途径。【结果】 BIG1和BIG2的siRNA干扰效率均高于70 ...
doaj
[Systemic lupus erythematosus complicated by autoimmune nodopathy: A case report]. [PDF]
Beijing Da Xue Xue Bao Yi Xue BanWei C, Yang Y, Zhao X, Liu X, Jia Y.
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[Expression of the melanoma 2-mediated pyroptosis pathway in peripheral blood mononuclear cells of patients with idiopathic inflammatory myopathies]. [PDF]
Beijing Da Xue Xue Bao Yi Xue BanChu J +6 more
europepmc +1 more source
[Progress of scRNA-seq technology in nasopharyngeal carcinoma research]. [PDF]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za ZhiZheng B, Jin G.
europepmc +1 more source
[The Impact of Oral Microecology on the Development of Inflammatory Bowel Disease]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue BanWan K, Yang C, Chen N, Chen F.
europepmc +1 more source