Results 121 to 130 of about 899,070 (159)

PGC-1α通过上调SIRT3表达发挥心肌保护作用

Zhongshan Daxue xuebao. Yixue kexue ban, 2016
摘 要: 【目的】探讨第III类组蛋白去乙酰化酶成员3(SIRT3)在过氧化物酶体增殖物受体γ共激活因子1α(PGC-1α)的调控下发挥改善心肌肥大和心肌能量代谢的作用?【方法】 建立血管紧张素II(Ang II)诱导的心肌肥大模型;利用质粒转染诱导PGC-1α基因过表达?siRNA干扰敲低SIRT3表达;Western blot检测PGC-1α?SIRT3及心肌肥大标志蛋白肌球蛋白重链β(β-MHC)的水平?TMRE染色法测定线粒体膜电位;测定ATP含量;DHE染色法测定活性氧水平;qRT ...
doaj  

[Interpretation of the Expert Consensus Statement on the Role of Vitamin D in Metabolic Health]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Zhao Z, Zeng Y.
europepmc   +1 more source

[ZEB2 promotes glioblastoma progression by reprogramming lipid metabolism through the CYLD/FASN axis]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Chen Z, Chai P, Mao Y, Liu R, Song Y.
europepmc   +1 more source

[Research Advances on Mechanisms and Interventions of DNA Methylation-Regulated Aging-Related Imbalance in Bone Metabolism]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
He T, Li J, Mei Y, Xiao G.
europepmc   +1 more source

[Alcoholic liver disease: new insights into an undeniable challenge and strategies for prevention and treatment]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Tang CW.
europepmc   +1 more source

[Interpretation of key updates of the 2026 version of the APASL clinical practice guidelines for the management of chronic hepatitis B]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Liu HS, Ai XW, Sun YM, You H.
europepmc   +1 more source

[Advances in growth impairment associated with pediatric respiratory diseases]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Chen XW, Chen DH.
europepmc   +1 more source

[Prognostic value of palmitoyl-protein thioesterase-1 in gastric cancer and its regulatory role in tumor cell lipid metabolism]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Huang B, Gao Y, Xie J, Yan C, Gu M, Zhang Z, Guo J, Liu S, Wang Z, Yang Y, Zuo L, Chen D.   +11 more
europepmc   +1 more source

[Buffering effect of intensive lipid lowering on mortality risk in type 2 diabetic patients with chronic kidney disease and challenging glycemic management: a cohort study based on dual metabolic trajectories]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Wang X, Yang J, Liang S, Dong Z.
europepmc   +1 more source

[Interpretation of the 2025 Asian Federation of Osteoporosis Societies (AFOS) Clinical Consensus: Atypical femoral fractures in patients with osteoporosis]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Xie M, Kong Q.
europepmc   +1 more source