Results 21 to 30 of about 899,070 (159)
Highlights Diabetes may predispose COVID‐19 hospitalized patients to worse clinical outcomes. Our findings indicate that diabetes is significantly associated with increased odds of severe COVID‐19, acute respiratory distress syndrome, mortality, and need for mechanical ventilation in hospitalized patients.
Sian A. Bradley +4 more
wiley +1 more source
Highlights In patients with hypertension and diabetes, early detection and intervention of insulin resistance and related risk factors in patients with normal BMI may reduce the occurrence of urinary microalbumin and delay the progression of CKD. Abstract Background The relationship between albuminuria and insulin resistance (IR) has not been clarified
Shi Gu +4 more
wiley +1 more source
目的 本国际临床指南由欧洲残疾儿童学会(the European Academy of Childhood Disability,EACD)牵头制定,旨在解决发育性协调障碍(developmental coordination disorder,DCD)的定义、诊断、评估、干预以及与社会心理方面的临床应用关键问题。 方法 本指南针对五个领域的关键问题,通过文献综述和专家团队的正式讨论达成共识。为保证指南的循证基础,以“机制”、“评估”和“干预”为检索词, 对2012年更新以来提出的最新建议以及新增的“社会心理问题”和“青少年/成人”为检索词进行检索。根据牛津大学循证医学中心证据等级 (证据水平 [level of evidence, LOE]1–4) 将结果进行分类,最终转化为指南建议。并由国际 ...
Jing Hua +6 more
wiley +1 more source
Background In the last decade, olanzapine became widely used in mental health service worldwide even after being criticized for its metabolic side effects. Patients with schizophrenia on olanzapine were usually found to stay on their medications longer than the other second‐generation antipsychotics (SGAs) except clozapine.
Hongbo He +5 more
wiley +1 more source
介绍针灸促进胃黏膜损伤修复的代谢机制,重点从针灸在胃黏膜损伤修复的氨基酸代谢、脂代谢、糖代谢等几个方面探讨其机理,认为针灸可通过调节以上3个方面的代谢途径实现胃黏膜修复,并提出代谢组学在中医应用的展望。广东省自然科学基金项目(2017A030313748)深圳市卫生计生委科研项目(201607061)深圳市福田区卫生公益性科研项目 ...
杨宗保, 杨锦兰, 冯军, 谢宇锋
core +1 more source
Read the free Plain Language Summary for this article on the Journal blog. Abstract Root activity creates unique microbial hotspots in the rhizosphere by influencing the metabolic activities of surrounding soil microorganisms, profoundly regulating the dynamics of soil organic carbon (SOC). However, how root economic strategies affect the formation and
Qiyu Tan +8 more
wiley +1 more source
A terminology (or coding system) is a formal set of controlled vocabulary in a specific domain. With a well‐defined terminology, each concept in the target domain is assigned with a unique code, which can be identified and processed across different medical systems in an unambiguous way.
Yinsheng Zhang +2 more
wiley +1 more source
氢谱磁共振代谢组学在2型糖尿病特征代谢物监测中的应用 [PDF]
目的应用氢谱磁共振(~1H-NMR)代谢组学方法研究2型糖尿病(T2DM)患者尿液中小分子代谢物代谢轮廓的变化。方法选择T2DM患者98例及健康对照组82例,利用~1H-NMR方法检测尿液的代谢轮廓,结合偏最小二乘判别分析法的模式识别分析方法,比较两组尿液中小分子代谢物差异。结果尿液的偏最小二乘判别分析法得分图显示与T2DM有关的特征代谢物包括乙酸、乳酸、牛磺酸、乙酰乙酸、葡萄糖、丙氨酸、甲基丙二酸、肌酐、柠檬酸、三甲胺等。结论糖代谢紊乱、氧化应激、氨基酸及脂类代谢异常 ...
张志军, 马红, 董继扬
core
Read the free Plain Language Summary for this article on the Journal blog. Abstract Grasslands worldwide are experiencing severe degradation due to overgrazing, climate change and anthropogenic disturbances, resulting in substantial declines in biodiversity and ecosystem functioning.
Xiaoqi Wang +5 more
wiley +1 more source
Read the free Plain Language Summary for this article on the Journal blog. Abstract Root exudates play a key role as signals and nutrients in mediating plant–microbe communication. However, critical knowledge gaps remain regarding how root exudates mediate soil–microbe–plant interactions to regulate crop yield under long‐term straw mulching combined ...
Jiajie Song +7 more
wiley +1 more source

