Results 21 to 30 of about 3,161 (182)
ABSTRACT Moderating harmful and offensive content on social media is challenging for digital platforms that seek to balance regulation and censorship across a diverse user group. It is further complicated by discrepancies between platform policies, user expectations and user experiences.
Asher Flynn +4 more
wiley +1 more source
Analysis on amide synthase and methyltransferase in biosynthesis of streptovaricin from the strain NRRL 2494 [PDF]
曲张链菌素(streptovaricin)是由壮观链霉菌(Streptomycesspectabilis)NRRL2494产生的安莎类抗生素,与抗结核药物利福霉素具有相似的化学结构骨架,具有抗菌及免疫抑制等多种生物活性。本论文在对NRRL2494菌株基因组测序的基础上,获得曲张链菌素生物合成基因簇,并通过构建稳定的遗传操作体系,研究其生物合成途径中重要基因的功能,为利用组合生物学手段获得成药性好的曲张链菌素类化合物奠定基础。 本论文首次分析了NRRL2494菌株的基因组全长17.5MB序列 ...
宋姣姣
core
Child Rights Impact Assessment: A Policy Tool for a Rights‐Respecting Digital Environment
ABSTRACT Businesses that develop digital products and services often anticipate generic users, paying insufficient attention to the needs and rights of children who may use or be impacted by their practices. This article investigates the potential of child rights impact assessment (CRIA) as a policy tool to protect and respect children's rights in the ...
Sonia Livingstone, Kruakae Pothong
wiley +1 more source
动物福利,就是让动物在健康、快乐的状态下生存。从动物福利运动兴起至今,许多国家和国际组织在动物福利方面已经制定或即将制定相应的法律、法规、标准和准则。中国是一个农业大国,尽快制定出适合国情的动物福利法律、法规及标准,提高我国的动物福利水平,已显得十分紧迫和必要。
马纲, 张敏
doaj
目的评价探针熔解曲线技术检测结核杆菌耐药效果。方法利用探针熔解曲线技术对46例涂阳肺结核患者的痰标本进行异烟肼和利福平耐药检测,以传统罗氏药敏试验为金标准,对探针熔解曲线技术的检测效果进行评价。结果在46例菌株中,用探针熔解曲线进行异烟肼耐药基因检测,与罗氏药敏的符合率为91.3%,进行利福平耐药基因检测,符合率为84.8%。结论探针熔解曲线检测异烟肼和利福平的耐药性与罗氏药敏方法具有很好的一致性,具有简便快速,灵敏度高,特异性好的优点,对临床及时准确进行抗结核治疗具有重要意义。沈阳市科技计划项目 ...
孙娇, 孙炳奇, 张娟, 张婷
core
Conservation benefits of a large marine protected area network that spans multiple ecosystems
Abstract Marine protected areas (MPAs) are widely implemented tools for long‐term ocean conservation and resource management. Assessments of MPA performance have largely focused on specific ecosystems individually and have rarely evaluated performance across multiple ecosystems either in an individual MPA or across an MPA network.
Joshua G. Smith +23 more
wiley +1 more source
目的评价基因芯片技术在结核病防治工作中对结核分枝杆菌异烟肼和利福平耐药性的检测效果。方法利用基因芯片技术对38例涂阳肺结核患者的痰标本进行异烟肼和利福平耐药检测,以传统罗氏药敏试验为金标准,对基因芯片技术的检测效果进行评价。结果在38例菌株中,用基因芯片法进行异烟肼耐药基因检测,与罗氏药敏的符合率为84.2%,对38例进行利福平耐药基因检测,符合率为89.5%。结论基因芯片检测异烟肼和利福平的耐药性与罗氏药敏方法具有很好的一致性,具有简便快速,灵敏度高,特异性好的优点 ...
孙炳奇 +4 more
doaj
The common welfare human resource management system and innovativeness: the mediating role of altruism [PDF]
Purpose – The paper analyzes and develops Chiva's (2014) proposal on the common welfare HRM system and uncovers its relationship with innovativeness, using altruism as a mediator.
Francisco Fermín Mallén-Broch +3 more
doaj +1 more source
The establishment and mechanism research in the mice model of actue liver failure [PDF]
背景和目的:急性肝衰竭(acuteliverfailure,ALF)是一个危及生命的严重病理生理状态。它可导致肝脏合成、排泄、解毒、生物转化等功能发生严重障碍或失代偿,出现凝血功能障碍、黄疸以及肝性脑病等主要表现的临床综合征。因其死亡率极高,严重ALF的治疗是当今临床医学中最具有挑战的课题之一。为了有效地治疗ALF,制备与ALF发病经过相同、临床表现类似并可复制的物模型是解决此难题的第一步,而了解各种ALF动物模型的构建机制就显得尤为重要。本课题以氧化偶氮甲烷(azoxymethane,AOM ...
金丽鑫
core
Influencing factors for recurrence after successful treatment in pulmonary tuberculosis patients with isoniazid resistance in Shaoxing City, Zhejiang Province [PDF]
ObjectiveTo analyze the influencing factors for recurrence in successfully treated pulmonary tuberculosis patients with isoniazid-resistant and rifampicin-sensitive in Shaoxing City, Zhejiang Province.MethodsData on general demographic information ...
GAO Huaqiang +6 more
core +1 more source

