Studies on the Extraction and Pharmacokinetics of Acacetin [PDF]
野菊花为菊科植物野菊、北野菊或岩香菊的头状花序。野菊花中主要含有挥发油、野菊花素A、刺槐苷(acaciin)、蒙花苷等成分。具有治疗各种炎症,治疗各种病毒性疾病以及清热解毒等功效,具有较高的药用保健价值,并且临床不良反应较少,慢性给药亦无蓄积中毒现象。 野菊花中含有刺槐苷,而刺槐苷的水解产物刺槐素(acacetin)具有抗炎、抗过氧化、抑菌、促进白血球吞噬等作用。刺槐素可以抑制肿瘤细胞的生长,具有良好的抗肿瘤应用前景,有望成为抗肿瘤的新药。 但国内外关于刺槐素提取分离工艺的文献报道较少 ...
朱性海
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Study on the rheology of xanthan and synergistic interaction with konjac gum and other gum [PDF]
研究前期筛选获得一株多糖胶质高产菌Xanthomonas axonopodis所产的黄原胶FJAT-10151-DTJZ的品质,为该黄原胶的开发应用提供基础数据及参考。通过分析浓度、剪切速率、p H、加热温度、时间、冻融处理等对FJAT-10151-DTJZ粘度的影响研究其流变性,并研究其与结冷胶、黄原胶、凝胶多糖、瓜尔豆胶、刺槐豆胶、魔芋胶、果胶和壳聚糖8种胶的协效性。实验结果表明,FJAT-10151-DTJZ溶液的粘度随浓度的升高而升高,且为非牛顿流体;当FJAT-10151-DTJZ的浓度为1 ...
刘波 +6 more
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Preparation of Ternary-component Sodium Alginate- Low-methyl Pectins-Locust Bean Gum Film and Its Application in Explosion Puffing Drying of Shiitake Mushrooms [PDF]
This study focused on the preparation of a ternary composite edible film using sodium alginate (SA), low-methoxyl pectin (LMP), and locust bean gum (LBG) as film-forming materials. The film, termed sodium alginate-low-methoxyl pectin-locust bean gum (SPL)
Dawei CHANG +7 more
core +1 more source
The Anticancer Mechanism of Acacetin Targeting RARγ and Regulating AKT-p53 Signal Pathway [PDF]
视黄酸受体(RARα、RARβ和RARγ)是核受体超家族中重要的一员,在细胞生长、增殖、免疫、分化、代谢、凋亡、自噬和自稳态等生物学过程中发挥重要的作用,是人类实体瘤和血液恶性肿瘤极好的药物治疗靶标。最近,我们和其他实验室的研究人员已经报道,RARγ在多种肿瘤中高度表达,通过激活PI3K/AKT这条生存通路,扮演促癌蛋白的角色。 在本研究中,我们进一步研究了RARγ介导的PI3K/AKT信号通路在癌细胞中的调节,并发现了一种活性黄酮类物质刺槐素(5,7-二羟基-4’-甲氧基黄酮 ...
曾文军
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Preparation of W/O/W Pickering emulsion based on ursolic acid [PDF]
Objective: This study aimed to improve the application range and bioavailability of ursolic acid. Methods: The W/O/W pickering emulsion was prepared by a two-step process with ursolic acid as emulsifier and pectin as external aqueous phase.
LIU Cheng-guo +5 more
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选择晋西黄土区蔡家川流域5种典型林地(山杨×辽东栎天然次生林、人工油松×刺槐混交林、人工油松林、人工刺槐林、人工侧柏林)作为研究对象,在每块样地中心布设1个土壤水分观测点,采用TRIME-TDR土壤水分测定仪定位观测2016—2018年1—12月的土壤体积含水量,测定深度为200 cm,每20 cm为1个测层,每月分上、中、下旬进行土壤水分含量观测,分析不同林地类型土壤水分年内变化规律和土壤水分垂直变化规律。结果表明:(1)研究区不同林地土壤水分年内变化可以划分为稳定期(1—3月)、波动期(4—6月 ...
赵丹阳 +7 more
doaj
Tianshui's Three Treasures: Water and Soil Conservation in Wartime Northwest China [PDF]
In addition to examining how wartime imperatives shaped the agricultural research, demonstration, and extension programs undertaken by the Nationalist government’s Tianshui Water and Soil Conservation Experiment Area (the Experiment Area) after its ...
Muscolino, Micah S
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为研究晋西黄土区不同密度刺槐人工林对土壤水分的影响,分别选取2 400株/hm2与1 300株/hm2刺槐人工林代表研究区高、低密度刺槐林分,以裸地为对照,分别利用Enviro-SMART土壤水分定位监测系统和翻斗式自记雨量计对0—150 cm深度范围内各土层体积含水量与林外降雨进行定位观测。结果表明:(1)从不同降水年份来看,在干旱年和平水年,低密度刺槐生长季平均土壤储水量高于高密度刺槐,在研究年份中,低密度刺槐多年平均土壤储水量比高密度刺槐多年平均土壤储水量高6.80 mm。(2)在土壤剖面垂直方向,
王宁 +6 more
doaj
The Anticancer Mechanism of Acacetin Targeting RARγ/PI3K/AKT Signal Pathway [PDF]
视黄酸受体(RetinoicAcidReceptor,RAR)是核受体家族中的重要一员,其在细胞生长、增殖、分化、免疫、代谢、凋亡及自噬等过程中发挥着重要作用。经典理论认为,视黄酸受体发挥其多效性生物学功能的机制是通过调控相关基因的表达,但随着研究的深入,其非基因型功能逐渐受到人们的重视。我们发现视黄酸受体亚型之一RARγ具有独特的胞质定位。在高密度培养、生长因子刺激等情况下,RARγ可由细胞核定位到细胞质中,并与细胞质中的PI3K调节亚基p85α相互作用,激活下游激酶AKT,进而活化NF-κB通路 ...
刘金星
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Soil Water Characteristics of Different Aerial-seeded Plant Communities at Northeastern Edge of Tengger Desert [PDF]
[Objective] Soil water characteristics of different plant communities at different slope positions on aerial-seeded afforestation areas in 1992 were studied at the northeastern edge of the Tengger Desert in order to provide a theoretical basis for the ...
Ge Nan +4 more
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