抗体药物偶联物治疗转移性去势抵抗性前列腺癌研究进展 [PDF]
浙江大学学报. 医学版转移性去势抵抗性前列腺癌（mCRPC）患者因肿瘤异质性和耐药性预后不佳，抗体药物偶联物（ADC）治疗mCRPC部分临床试验中已展现出抗肿瘤活性及较好的安全性。在靶向前列腺特异性膜抗原（PSMA）的ADC中，相较于早期ADC如MLN2704、PSMA-ADC、MEDI3726，ARX517安全性更优，前列腺特异性抗原下降更显著。在靶向B7-H3的ADC中，MGC018和DB-1311也展现出抗肿瘤活性。靶向前列腺六跨膜上皮抗原（STEAP）1的DSTP3086S、靶向滋养层细胞表面抗原（TROP ...
徐 嘉程 +5 more
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磁共振结合经直肠超声在各PSA 区间对前列腺癌的诊断价值 [PDF]
Zhongshan Daxue xuebao. Yixue kexue ban, 2017 摘要：【目的】探讨磁共振（MRI）结合经直肠超声（TRUS）在不同前列腺特异性抗原（PSA）区间对前列腺癌的诊断价 值。【方法】搜集2014年11月至2016年6月在我院的278例患者的临床资料。纳入研究的病例穿刺前均进行了PSA血清学 检查，MRI 以及TRUS 的影像学检查。278 例患者分别按PSA 水平4 ~ 10 ng/mL、10 ~ 20 ng/mL、大于20 ng/mL 分为A、B、C 3组。对3组的MRI结合TRUS的诊断率进行了回顾性分析。【结果】A组MRI ...
苏冠宇 +6 more
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Zhongshan Daxue xuebao. Yixue kexue ban, 2013 【目的】 探讨经直肠超声引导的前列腺穿刺中前列腺体积(PV)、前列腺特异性抗原密度(PSAD)与前列腺癌(Pca)检出率之间的关系。 【方法】 分析2008年7月至2011年5月间在我院行前列腺穿刺262例患者的临床资料,了解PSAD、PV与Pca检出率之间的关系。所有穿刺病例在行穿刺术前均行前列腺特异性抗原(PSA)、直肠指诊(DRE)及经直肠超声(TRUS)扫描测量PV水平并计算得出前列腺特异性抗原密度(PSAD)。 【结果】 在总计262例前列腺穿刺的病例中,有101例经病理确诊为Pca ...
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Zhongshan Daxue xuebao. Yixue kexue ban, 2016 摘 要: 【目的】 分析前列腺癌病人的多种临床指标与其3年生存的相关性,为前列腺癌病人预后判断提供依据?【方法】 回顾性随访分析341名前列腺癌病人的资料,计算3年总生存率,并应用单因素相关分析及多因素logistic回归分析年龄(AGE)?总前列腺特异性抗原(TPSA)?直肠指检(DRE)?经直肠B超结果(TRUS)?前列腺特异性抗原密度(PSAD)?前列腺移行区体积密度(PSATZ)?肿瘤T2分期,转移情况?Gleason 评分?是否接受治疗等指标与病人3年生存的相关性 ...
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Value of 18F-PSMA PET/MRI for early diagnosis of recurrence and metastasis in prostate cancer patients after radical prostatectomy [PDF]
, 2023 Objective: To investigate the value and significance of 18F-prostate-specific membrane antigen (18F-PSMA)-1007 PET/MR for early diagnosis of recurrence and metastasis in prostate cancer patients after radical prostatectomy (RP).
ZHOU Yilei, ZHANG Miao, GUO Rui, ZHOU Jinxin, LI Biao, LI Xiang
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Research progress in the relationship between plasma FIB and prostate cancer [PDF]
, 2023 The incidence of prostate cancer （PCa） has been increased year by year， mainly occurring in elderly men. Currently， prostate-specific antigen （PSA） is still used as a marker for diagnosing PCa in clinical practice.
Zhang Peng, Han Conghui, Liu Dachuang
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Latent profile analysis of adverse effects associated with endocrine therapy in prostate cancer patients based on the theory of unpleasant symptoms [PDF]
, 2023 Objective·Based on the theory of unpleasant symptoms, to investigate the current status of adverse effects associated with endocrine therapy in prostate cancer patients, and identify the difference of population specificity in each latent category ...
YANG Yan +3 more
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Interpretation of US cancer statistics 2023 and its implications for cancer prevention and treatment in China [PDF]
, 2023 In the year 2023, 1 958 310 new cancer cases and 609 820 cancer deaths are projected to occur in the United States, estimated by Cancer Statistics, published by American Cancer Society.
ZHOU Changming, WANG Zezhou, ZHENG Ying
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Analysis of Detection of Mixed Semen Stains with Different Immunological Test Methods and Case Applications [PDF]
, 2019 Objective To perform the separation and confirmation of mixed semen stains with immunological test method, and find a more effective method for the detection of mixed semen stains. Methods The semens of three volunteers were mixed. The mixed semen stains
DONG Min-an, LI Mei-li, CAI Ming-sheng
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Advances in basic research, clinical diagnosis and treatment of prostate cancer in 2022 [PDF]
, 2023 About 40%-70% of newly diagnosed prostate cancer patients in China are in the stage of metastatic disease, and the spatio-temporal heterogeneity of the occurrence and development of prostate cancer and the unique metastasis pattern make it difficult to ...
PAN Jian, ZHU Yao, DAI Bo, YE Dingwei
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