Results 11 to 20 of about 4,207 (149)
超声弹性成像与磁共振弥散成像引导穿刺活检前列腺癌诊断的对比研究 [PDF]
Zhongshan Daxue xuebao. Yixue kexue ban, 2019 【目的】对比分析经直肠超声实时弹性成像（TRTE）和磁共振弥散成像（DWI）对前列腺癌的诊断效能，探讨两者靶向引导前列腺穿刺活检的价值及与Gleason评分之间的关系。【方法】选取126例疑诊为前列腺癌的患者，穿刺活检前均行TRTE和DWI检查，结合病理结果比较TRTE和DWI对前列腺癌的诊断效能，评估两者引导前列腺穿刺活检的准确性，分析超声弹性评分和ADC值与Gleason评分之间的相关性。【结果】TRTE诊断前列腺癌的敏感度、特异度和准确性为78.8%、78.3%和78.6 ...
鲁虹霞
doaj +2 more sources
生育酚结合蛋白通过磷酸肌醇3激酶途径抑制前列腺癌的生长 [PDF]
Zhongshan Daxue xuebao. Yixue kexue ban, 2007 【目的】探讨生育酚结合蛋白（TAP）对前列腺癌细胞的生长调节及其分子机制。【方法】四甲基偶氮唑盐生长试验（MTY）测定细胞增殖情况，体外集落形成试验测定各细胞的致癌能力，高效液相层析法检测细胞内维生素E的浓度，利用基因转染、基因沉默、免疫印迹、Northem blot，RT-PCR、荧光定量PCR、免疫沉淀等方法研究TAP对前列腺细胞生长的作用及机制。【结果】TAPmRNA水平在前列腺癌细胞LNCaP、PC-3、DU-145、CWR22R中均较正常前列腺细胞RWPE-1低 ...
温星桥 +7 more
doaj +2 more sources
Zhongshan Daxue xuebao. Yixue kexue ban, 2004 【目的】构建前列腺癌患者的噬菌体抗体库,为前列腺癌特异性的人源性抗体Fab片段的筛选及其应用奠定基础。【方法】由前列腺癌患者外周血分离得淋巴细胞,完整提取其总RNA,经RT-PCR及半套式扩增得到免疫球蛋白全部轻链和重链Fd段基因,然后经酶切、纯化、连接等步骤克隆进载体pComb3,并电转化大肠杆菌XL1-Blue,从而构建前列腺癌患者噬菌体抗体库。【结果】成功构建噬菌体抗体Fab片段库,其轻链及重链Fd段与载体DNA的重组率分别为87%、79%,库容为23.2×107,滴度为87×1012mL-1 ...
doaj +2 more sources
Zhongshan Daxue xuebao. Yixue kexue ban, 2019 【目的】利用生物信息学的方法，对GEO和TCGA两个基因组学数据库进行分析，探究与前列腺癌相关的差异基因及相关的调控网络。【方法】综合GEO数据库的前列腺癌基因表达芯片数据（GSE46602、GSE55945）和TCGA数据库的RNA-seq数据，利用GEO2R及R语言的edgeR包进行基因差异分析，获得共同的显著差异基因，结合R语言的clusterProfiler包进行GO功能分析及KEGG通路分析，同时利用string网站进行蛋白互作网络分析，筛选出前列腺癌中调节蛋白表达量的关键基因 ...
李志标
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Journal of Diabetes, Volume 13, Issue 12, Page 1007-1014, December 2021., 2021 Highlights This prospective study compares 15 patients with immune‐checkpoint induced diabetes mellitus (CPI‐DM) with a propensity score matched cohort of patients with other diabetes types. Diabetic ketoacidosis at onset and autoimmune comorbidity is more frequent in CPI‐DM patients. This can be avoided by regular glucose measurements and education on
Sascha R. Tittel +10 more
wiley +1 more source
Impact of skeletal-related events on survival in patients with metastatic prostate cancer prescribed androgen deprivation therapy [PDF]
, 2016 published_or_final_versio
Ho, KL +7 more
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Delays and Barriers to Cancer Care in Low‐ and Middle‐Income Countries: A Systematic Review
The Oncologist, Volume 24, Issue 12, Page e1371-e1380, December 2019., 2019 Abstract Background Advanced stage presentation of patients with is common in low‐ and middle‐income countries (LMICs). A comprehensive analysis of existing delays and barriers in LMICs has not been previously reported. We conducted a systematic literature review to comprehensively outline delays and barriers to identify targets for future ...
Nathan R. Brand +3 more
wiley +1 more source
, 2002 目的 提高晚期前列腺癌并发症的治疗水平。方法 对 42例晚期前列腺癌患者分别出现的骨痛、贫血、尿路梗阻、顽固性血尿及下肢水肿等并发症分别给予多种止痛剂、博宁、氯化锶、外放射、间断输血、经尿道前列腺电切术等治疗。结果 42例患者中 1 8例死亡 ,2 4例存活 ;结论 ...
王晓峰, 白培明
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Research progress in the relationship between plasma FIB and prostate cancer [PDF]
, 2023 The incidence of prostate cancer （PCa） has been increased year by year， mainly occurring in elderly men. Currently， prostate-specific antigen （PSA） is still used as a marker for diagnosing PCa in clinical practice.
Zhang Peng, Han Conghui, Liu Dachuang
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Value of 18F-PSMA PET/MRI for early diagnosis of recurrence and metastasis in prostate cancer patients after radical prostatectomy [PDF]
, 2023 Objective: To investigate the value and significance of 18F-prostate-specific membrane antigen (18F-PSMA)-1007 PET/MR for early diagnosis of recurrence and metastasis in prostate cancer patients after radical prostatectomy (RP).
ZHOU Yilei, ZHANG Miao, GUO Rui, ZHOU Jinxin, LI Biao, LI Xiang
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