Results 11 to 20 of about 18,866 (201)

Justice in coexistence: Pastoralism and large carnivores on the Qinghai‐Tibet Plateau

open access: yesPeople and Nature, EarlyView.
Abstract The conflict between livestock husbandry and large carnivore conservation presents significant challenges in grassland ecosystems worldwide. Achieving sustainable coexistence among herders, livestock and large carnivores requires reconciling diverse perspectives and interests through equitable, inclusive and fair processes that address both ...
Yufang Gao, Yue Yu
wiley   +1 more source

The Th cell subsets analysis of syphilis patients and mechanism of Treponema pallidum infection [PDF]

open access: yes, 2016
梅毒是由梅毒螺旋体引起的性传播疾病。梅毒螺旋体可侵入人体各个组织器官,引起各种临床表现。目前机体对梅毒螺旋体的免疫机制尚不清楚。本课题分别从体内和体外实验分析梅毒螺旋体引起的初始Th细胞分化,初步探讨梅毒螺旋体细胞免疫机制。我们分析32例梅毒患者外周血辅助性T细胞(Th)亚群含量变化;通过兔皮内接种模型,分析梅毒螺旋体感染后局部炎症反应中IFN-γ和IL-4mRNA的表达随时间变化情况。体内研究发现梅毒螺旋体感染后细胞免疫应答在人外周血和兔皮损中IFN-γ含量明显升高,Th1型细胞增多 ...
张巧
core  

The Dependence of Properties on Structural Features in Macro/Micro Levels for PBF‐LB Fabricated Porous NiTi Alloy

open access: yesRare Metals, EarlyView.
ABSTRACT Porous NiTi alloys are widely used in biomedical and engineering fields. Using the PBF‐LB technique, the TPMS and Voronoi porous parts with a porosity of ∼67% and a minimum feature size of 0.15 ± 0.02 mm were fabricated. Although the bulk sample fabricated with the same parameters is defect‐free, μ‐CT reconstruction on the porous sample ...
Wen‐Hao Zeng   +7 more
wiley   +1 more source

The Role and Mechanism of MicroRNA-219 in Epileptogenesis [PDF]

open access: yes, 2015
目的:通过海人酸、匹罗卡品诱导C57BL/6、ICR小鼠癫痫持续状态发作,制造人类颞叶癫痫动物模型,探讨microRNA-219在癫痫发病中的功能通路及调控网络的动态变化,为癫痫的诊断提供新的依据,为抗痫药物研制提示新的作用靶点。 方法:用成年雄性C57BL/6、ICR小鼠为研究对象,侧脑室注射海人酸(Kainicacid,KA)或腹腔注射匹罗卡品诱发小鼠癫痫发作,建立小鼠癫痫动物模型。24小时后检测小鼠皮质脑电图改变并运用荧光定量PCR方法检测小鼠海马和皮质中microRNA-219表达变化情况 ...
唐荣
core  

Laser‐Driven Halide Exchange and High‐Resolution Multicolor Patterning of Perovskite Films

open access: yesRare Metals, EarlyView.
ABSTRACT Translating the excellent properties of metal halide perovskites (MHPs) into practical flexible optoelectronic devices requires high‐resolution multicolor patterning techniques that are compatible with post‐fabrication processing. However, such a capability has remained elusive.
Shu Yang   +6 more
wiley   +1 more source

利用生物地球化学模型研究草地生态系统土地变化对生态环境的影响

open access: yesShuitu Baochi Xuebao, 2003
分析了生物地球化学循环中植物—土壤生态系统的有机物动态,土壤有机质(SOM)主要库类——土壤C,N,P,S循环特点;阐述了土壤有机质的生物地球化学循环模型CENTURY结构。利用CENTURY模型模拟土地利用变化情形下内蒙古草原生态典型区土壤有机质动态。由数值模拟结果分析看,CENTURY对自然和人为活动影响下生态系统的土壤有机质动态有良好的模拟能力,同时又可有效地反映土地利用类型变化对生态环境和土壤侵蚀的影响。
张佳华 徐永福 等
doaj   +2 more sources

Establishment and Application of Respiratory Syncytial Virus Animal Model [PDF]

open access: yes, 2016
人呼吸道合胞病毒(HumanRespiratorySyncytiaVirus,hRSV)是全球范围内引起下呼吸道感染主要病原体之一。其感染人群年龄分布广,新生儿与老年人是主要高危人群。据报道,几乎所有小于2周岁婴幼儿都有RSV感染经历,婴幼儿发病住院率高达2.5-4%。RSV引起大于65周岁的老年人感染率为3-4%,病死率约为2%。早产儿、先天性心脏病、先天性支气管及肺发育不良、免疫缺陷的婴幼儿RSV病死率率高达5%,造成严重的医疗负担。 RSV无安全、有效疫苗上市 ...
詹炉停
core  

Rational Design of Multifunctional Nano–Architected Coatings for Bipolar Plates in Proton Exchange Membrane Fuel Cells

open access: yesRare Metals, EarlyView.
ABSTRACT Proton exchange membrane fuel cells (PEMFCs) require advanced bipolar plate coatings to enhance efficiency, durability, and commercialization potential. This review presents a systematic framework for evaluating and designing bipolar plate coatings, integrating material selection, performance metrics, deposition techniques, and future ...
Shijie Li   +12 more
wiley   +1 more source

The establishment of new organ transplant models for immune rejection and the exploration of the mechanisms of transplantation immunity [PDF]

open access: yes, 2015
目的:建立两种新型的器官移植排斥反应模型,即树鼩异种心脏移植模型以及使用套管法建立新型小鼠主动脉移植模型,并分别对这两种器官移植模型中的异种移植免疫排斥机制和慢性排斥反应机制进行初步探索。 方法:1.采用腹部异位心脏移植的方法建立树鼩到SD大鼠,SD大鼠到树鼩的异种心脏移植模型,对比树鼩与大鼠的解剖数据,分析模型的可行性,观察移植心脏的生存期及病理变化,观察模型的免疫排斥反应类型,进行免疫组化、微量淋巴毒实验、混合淋巴实验以进行机制的初步探讨。2.利用套管法将供体BALB ...
伍源
core  

Hybrid Probiotic Hydrogel With Curcumin‐Loaded MnO2 Nanoparticles Enhances Diabetic Wound Healing Through Multimodal Microenvironmental Regulation

open access: yesRare Metals, EarlyView.
ABSTRACT Skin wound injuries are often accompanied by bacterial infections and severe inflammation. Especially, M1‐type macrophages at the wound site can trigger a cascade of inflammatory responses, mediating a vicious cycle of inflammation. Meanwhile, hypoxia further exacerbates vascular damage and constriction in the wound microenvironment, thereby ...
Xianfeng Wang   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy