Results 11 to 20 of about 495 (146)
, 2017 动脉粥样硬化是一种较为严重的心脑血管疾病,对人体健康有着十分严重的危害。在临床上,通心络胶囊是一种常用的药物,能够有效的保护心脏、血管、血液,对于脑梗死、心肌梗死、冠心病、动脉粥样硬化等疾病的治疗中,均可发挥出良好的效果。在实际治疗中,药物可通过稳定斑块、调节血脂、改善心功能、缓解急性冠状动脉综合征等作用 ...
方鉴
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外源性硫化氢通过PI3K/Akt/eNOS通路改善过氧化氢诱导的人脐静脉内皮细胞衰老 [PDF]
, 2021 目的本研究拟探讨磷脂酰肌醇3激酶/蛋白激酶B/内皮型一氧化氮合酶（PI3K /Akt /eNOS）通路对硫化氢（H2S）改善内皮细胞衰老的作用。方法建立60 μmol/L过氧化氢（H2O2）诱导的人脐静脉内皮细胞（HUVEC）衰老模型；衰老模型的评估及不同浓度硫氢化钠（NaHS）预处理对衰老的作用均通过检测纤溶酶原激活物抑制剂1（PAI-1）的表达水平和衰老相关β-半乳糖苷酶（SA-β-Gal）染色阳性率来研究评估。同时通过Western blot法检测各组内皮细胞中蛋白激酶B（Akt）蛋白 ...
余显冠 +7 more
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Zhongguo cuzhong zazhi, 2019 目的 探讨腔隙性脑梗死（lacunar infarction，LI）认知功能障碍与颈动脉粥样硬化性斑块的关系。 方法 回顾性分析2017年1月-2018年11月就诊于海淀医院神经内科的符合LI诊断标准的患者171例，按照蒙特利尔认知评估量表（Montreal cognitive assessment scale，MoCA）评分分为认知功能障碍组和非认知功能障碍组，对颈动脉动脉粥样硬化性斑块与认知功能障碍之间的关系进行Logistic多因素回归分析。 结果 调整潜在混杂因素后 ...
杨兴东，曾一君，唐晓梅，冯研，史冬梅，刘磊，于逢春
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Research progress in biological activities and mechanisms of theabrownin [PDF]
, 2023 Tea is beneficial to human health, which is rich in tea pigments with important biological activities. Theabrownin, derived from theaflavins and thearubigins by oxidative polymerization, mainly distributes in semi-fermented oolong tea, and completely ...
JIA Wei +4 more
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Zhongguo cuzhong zazhi, 2022 目的 探索同侧非狭窄性颈动脉粥样硬化斑块特征与前循环不明原因栓塞性卒中（embolic stroke of undetermined source，ESUS）的相关性。 方法 回顾性纳入北京市大兴区人民医院神经内科2017年1月-2022年5月连续住院的急性单侧前循环缺血性ESUS患者。采用颈动脉超声评估双侧非狭窄性颈动脉粥样硬化斑块，比较梗死同侧颈动脉与对侧颈动脉斑块的发生率、多发斑块的发生率、不均质回声斑块的比例以及颈动脉斑块厚度等特征的差异。 结果 共纳入101例ESUS患者，平均年龄60.7±
徐莹鑫, 张爽, 周晓梅, 袁景林, 赵留庄, 杨海华
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Effects of sennoside A on atherosclerotic plaque formation and expression of 5-hydroxytryptamine signal moleculars in mice with diabetes mellitus type 2 [PDF]
Objective·To investigate the effects of sennoside A (SA) on the formation of atherosclerotic plaque and the expression of 5-hydroxytryptamine (5-HT) and its receptor in mice with diabetes mellitus type 2 (T2DM).Methods·Twelve mice with knocked-out ...
JIANG Yaning +4 more
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Distribution characteristics of coronary atherosclerotic plaque in patients with myocardial bridge of mid⁃left anterior descending coronary artery and influencing factors of plaque stability [PDF]
Objective To explore the relationship between myocardial bridge（MB）parameters and plaque distribution in patients with coronary atherosclerosis，as well as the factors influencing plaque stability.
CHEN Zhenmin*，Li Yanping，HE Huiqiong，WU Xi
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Growth and Development Trend of Lateral Plaques and Subsequent Plaques in Bifurcated Vessels: A Dynamic Simulation [PDF]
Objective To investigate vascular remodeling and low-density lipoprotein (LDL) deposition, the growth and development trends of lateral branch plaques in bifurcated vessels, and the potential locations of subsequent plaque growth due to the presence of ...
Du, T +7 more
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Comparison on the Treatments of Three Methods for Knee Osteoarthritis [PDF]
, 2017 目的 探讨膝关节骨性关节炎（knee osteoarthritis,KOA）的较佳治疗方案。方法 从双氯芬酸钠治疗组（A组）、正清风痛宁口服治疗组（B组）、正清风痛宁关节腔注射与片剂序贯疗法组（C组）各随机抽取60例病例,比较3组治疗前后疗效、不良反应等指标。结果 3组患者治疗后的Lequesne指数均较治疗前下降（P均〈0.01）;A组治疗后的Lequesne指数与B组差异无统计学意义（P〉0.05）;C组治疗后的Lequesne指数均低于A组与B组（P均〈0.01）。A、B、C ...
方庆全, 陈丰庆, 陈宏
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麝香心脑乐片薄膜衣片减轻大鼠冠状动脉粥样硬化斑块负荷的机制研究
Zhongguo shiyan zhenduanxue, 2023 目的 探讨麝香心脑乐片薄膜衣片对冠状动脉粥样硬化斑块负荷的影响及作用机制。方法 90只大鼠随机分为3组，每组30只，包括模型组(高脂饲料+0.9%氯化钠盐溶液)、实验组(高脂饲料+麝香心脑乐薄膜衣片溶液)、空白对照组(普通词料饲养+0.9%氯化钠盐溶液),全部大鼠造模成功后连续灌胃8周。HE染色检测冠脉斑块大小及泡沫细胞含量，生化检测血清中总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)水平，ELISA法检测血清中白细胞介素-6(IL-6 ...
任航, 凌浩, 丁宛萱, 宋春莉
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