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运动训练促进脑卒中后神经可塑性的机制研究 [PDF]

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2021
运动训练是脑卒中后康复治疗的主要手段。运动训练可以促进脑卒中后神经功能的恢复,其作用目前普遍认为与神经可塑性有关,但具体机制未明。运动训练的神经可塑性机制是当前脑卒中康复研究领域的热点问题。运动训练可以调节脑卒中后脑内血流动力学变化、血管新生、神经炎症反应、营养因子分泌、神经细胞死亡及新生等。本文基于国内外研究,探讨脑卒中后最适的运动干预方案,并结合我们团队在运动训练促进脑卒中后神经功能恢复方向所做的系列研究工作,对运动训练促进脑卒中后神经可塑性的机制研究进行综述。
胡昔权
doaj   +2 more sources

肠道菌群与卒中后肺炎相关性的研究进展 Advances in the Correlation between Gut Microbiota and Post-stroke Pneumonia

open access: yesZhongguo cuzhong zazhi, 2023
近年来,肠道菌群被认为与卒中后肺炎有关,肠道菌群及其代谢产物通过神经-免疫影响卒中后肺炎,靶向调节肠道菌群如粪菌移植、补充益生菌/益生元有望成为控制卒中后肺炎的重要手段。本文从肠道菌群对卒中后肺炎的影响、可能作用机制及肠道菌群调节在卒中后肺炎治疗中的应用效果等方面进行综述,阐述了卒中后感染的一个易被忽视的重要传染源,以期促进卒中后肺炎靶向治疗策略的发展。 Abstract: In recent years, gut microbiota is considered to be related to
隋冉冉,山要中,赵兴军,陈南南,刘凤荣,逄锦晶
doaj   +2 more sources

中国卒中患者高血压管理专家共识 Chinese Expert Consensus on Hypertension Management in Stroke Patients

open access: yesZhongguo cuzhong zazhi
卒中后血压升高与患者死亡和神经功能恢复不良相关,积极有效地控制血压对改善预后非常重要。《中国卒中患者高血压管理专家共识》基于现有循证医学证据,对出血性卒中和缺血性卒中早期降压治疗的时机、目标和用药措施进行了推荐;考虑到临床实际中多病共存的现状,还对合并心力衰竭、颈部大血管狭窄、主动脉夹层、肾功能衰竭、心房颤动、肺部感染等特殊病情卒中患者的降压时机、目标和用药措施进行了推荐;同时就卒中一级、二级预防中的血压管理进行了介绍。《中国卒中患者高血压管理专家共识》的发布有利于临床实践中卒中患者高血压的规范化管理。
北京高血压防治协会,中国卒中学会高血压预防与管理分会 (Beijing Hypertension Association, Chinese Stroke Association Hypertension Prevention and Management Branch )
doaj   +2 more sources

脑卒中患者睡眠障碍的临床异质性研究 [PDF]

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2010
【目的】 探讨急性脑卒中患者睡眠障碍的临床异质性.【方法】 采用匹兹堡睡眠质量指数量表 (PSQI)对84例急性脑卒中患者与55例正常对照者的睡眠状况进行测评分析,同时采用Barthel指数(BI)与美国国立卫生研究院卒中量表(NIHSS)分别评价脑卒中患者的日常生活活动能力与神经功能缺损程度?【结果】 脑卒中组中睡眠障碍发生率(46.4%)明显高于对照组(16.4%)(P < 0.05);脑卒中组PSQI总分以及睡眠质量,入睡时间?睡眠障碍?催眠药物?日间功能障碍五因子得分均明显高于对照组(P < 0.
doaj   +1 more source

Association of glycemic gap with stroke recurrence in patients with ischemic stroke. [PDF]

open access: yesJ Diabetes, 2023
Highlights There was a U‐shaped relationship between glycemic gap and stroke recurrence during a long‐term follow‐up in a Chinese ischemic stroke registry. Clinical physicians should remain vigilant in the fluctuation of glucose level and use individualized glucose control strategies in patients with ischemic stroke.
Yuan K   +10 more
europepmc   +2 more sources

现状、挑战和展望:中国卒中急救地图 The Current Status, Challenges and Prospects of Stroke Emergency Map in China

open access: yesZhongguo cuzhong zazhi
卒中是中国居民致死致残的主要原因,给社会带来了极重的负担。面对这一严峻的卒中救治形势,卒中急救地图应运而生。卒中急救地图通过地理信息系统和人工智能等先进技术整合医疗资源,构建了涵盖急救、转运、治疗到康复全流程的卒中救治网络,可较为显著地提升卒中的急救效率并改善患者预后。作为创新技术平台,卒中急救地图在提升卒中急救效率和治疗效果方面至关重要。目前,中国卒中急救地图取得初步成效,且发展态势良好,然而在实际应用中,仍然面临一些重要挑战。为了更好地发挥地图的作用,未来的研究应着眼于如何完善这一平台,加强推广 ...
曹黎明1,廖雨琦1,2,池枫1,3,任力杰1,3 (CAO Liming1, LIAO Yuqi1,2, CHI Feng1,3, REN Lijie1,3 )
doaj   +2 more sources

组织化卒中管理模式对脑卒中患者住院时间和住院费用的影响 [PDF]

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2008
【目的】 评估组织化卒中管理模式对脑卒中患者平均住院时间和平均住院费用的影响?【方法】 自2002年1月至2006年12月的脑卒中患者共2 637例,随机进入组织化卒中管理病房和普通神经科病房,分别对他们治疗前后结果进行比较? 【结果】 组织化卒中管理模式的病死率较普通神经科病房明显减少;组织化卒中管理病房的平均住院时间为(21 ± 16)d,平均住院费用为(18 579 ± 20 984)元;普通神经科病房的平均住院时间为(21 ± 13)d,平均住院费用为(19 561 ±31 127)元 ...
doaj   +1 more source

A network meta‐analysis of association between cardiometabolic risk factors and COVID‐19 outcome severity 心血管代谢危险因素与COVID‐19严重程度关联的网络荟萃分析

open access: yesJournal of Diabetes, Volume 15, Issue 11, Page 968-977, November 2023., 2023
Highlights Among 301 studies, diabetes mellitus was the most studied cardiometabolic risk factor. In the network meta‐analysis, cerebrovascular disease had the highest impact (relative risk [RR] 1.69; 95% CI, 1.65–1.73) on COVID‐19 outcomes compared to other cardiometabolic risk factors.
Alina Binbin Li   +9 more
wiley   +1 more source

Associations between posttraumatic stress and stroke: A systematic review and meta‐analysis

open access: yesJournal of Traumatic Stress, Volume 36, Issue 2, Page 259-271, April 2023., 2023
Abstract The objective of the present study was to systematically review the existing literature for studies examining the association between posttraumatic stress disorder (PTSD) and stroke risk and perform a meta‐analysis to obtain a pooled risk estimate describing the association.
Hely D. Nanavati   +3 more
wiley   +1 more source

Association of alcohol consumption with all‐cause mortality, new‐onset stroke, and coronary heart disease in patients with abnormal glucose metabolism—Findings from a 10‐year follow‐up of the REACTION study 糖代谢异常患者饮酒与全因死亡率、新发卒中以及冠心病的关系——来自REACTION研究10年随访的发现

open access: yesJournal of Diabetes, Volume 15, Issue 4, Page 289-298, April 2023., 2023
Highlights This long‐term longitudinal study demonstrates the association between alcohol consumption and health outcomes in patients with abnormal glucose metabolism including type 2 diabetes mellitus and prediabetes. Occasional drinking (less than once a week) reduces the risk of all‐cause mortality, while heavy alcohol consumption (≥30 g/day for men
Mengzhao Cui   +7 more
wiley   +1 more source

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