Results 31 to 40 of about 19,973 (172)

Research on Chinese Question‐Answering for Gaokao Based on Graph

open access: yesMathematical Problems in Engineering, Volume 2020, Issue 1, 2020., 2020
Reading comprehension Question‐Answering (QA) for College Entrance Examination (Gaokao in Chinese) is a challenging AI task because it requires effective representation to capture complicated semantic relations between the question and answers. In this paper, a novel method of Chinese Automatic Question‐Answering based on a graph is proposed.
Zhizhuo Yang   +5 more
wiley   +1 more source

Single Point Mutation from E22‐to‐K in Aβ Initiates Early‐Onset Alzheimer’s Disease by Binding with Catalase

open access: yesOxidative Medicine and Cellular Longevity, Volume 2020, Issue 1, 2020., 2020
Amyloid‐beta (Aβ) is a critical etiological factor for late‐onset familial Alzheimer’s disease (AD). However, an early‐onset AD has been found to be related with an Aβ mutation in glutamic acid 22‐to‐lysine (Italian type E22K). Why only one single point mutation at E22 residue induces AD remains unclear.
Wenjing Jiang   +12 more
wiley   +1 more source

中国卒中报告2020(中文版)(1)

open access: yesZhongguo cuzhong zazhi, 2022
我国正面临着全球最大的卒中挑战。全球疾病负担(global b urden o f d isease,GBD)研究结果显示,2019年我国新发卒中394万例,卒中患者达到2876万例,卒中死亡人数为219万例。此外,卒中也是我国伤残调整生命年(disability-adjusted life years,DALYs)的首位原因,2019年卒中所致DALYs达到4590万。近期的几项大型流行病学调查对与卒中有关的既往疾病数据进行了更新。2018年我国18~69岁成人的超重和肥胖率分别为34.4%和16.8%
王拥军, 李子孝, 谷鸿秋, 翟屹, 姜勇, 周齐, 赵性泉, 王伊龙, 杨昕, 王春娟, 孟霞, 李昊, 刘丽萍, 荆京, 吴静, 徐安定, 董强, David Wang, 王文志, 马旭东, 赵继宗, 《中国卒中报告》编写委员会(第一作者)
doaj   +1 more source

卒中中心建设及质量控制研究进展 Research Progress of the Construction and Quality Control of Stroke Center

open access: yesZhongguo cuzhong zazhi, 2023
卒中中心建设及质量控制是近年来卒中救治领域的热点话题。我国的卒中中心建设通过医疗资源整合,多学科协作,形成了一个集院前识别与转运、急性期救治、早期康复、二级预防、随访宣教、质量检测及改进于一体的区域组织化卒中救治网络,建立了一套标准、高效、规范的卒中救治及质量控制体系,对规范和提升医疗机构卒中诊疗和效率,促进医疗服务质量改进,降低疾病负担起到了重要作用。急救地图建设着眼于如何在急救响应及急性期治疗环节减少包括院前识别、急救派遣等环节的时间延误,我国逐步构建了“国家-省-地级市”三级卒中急救地图体系 ...
高远,刘凯,李亚鹏,杨宗豫,李玉生,宋波,许予明
doaj   +1 more source

运动训练促进脑卒中后神经可塑性的机制研究

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2021
运动训练是脑卒中后康复治疗的主要手段。运动训练可以促进脑卒中后神经功能的恢复,其作用目前普遍认为与神经可塑性有关,但具体机制未明。运动训练的神经可塑性机制是当前脑卒中康复研究领域的热点问题。运动训练可以调节脑卒中后脑内血流动力学变化、血管新生、神经炎症反应、营养因子分泌、神经细胞死亡及新生等。本文基于国内外研究,探讨脑卒中后最适的运动干预方案,并结合我们团队在运动训练促进脑卒中后神经功能恢复方向所做的系列研究工作,对运动训练促进脑卒中后神经可塑性的机制研究进行综述。
胡昔权
doaj  

卒中后失眠的研究进展 Research Progress of Insomnia after Stroke

open access: yesZhongguo cuzhong zazhi, 2023
卒中后失眠是在卒中后首次出现并达到失眠诊断标准的一组临床综合征,与临床常见失眠相类似,主要表现为睡眠深度异常和平均每晚睡眠时间少于6 h。meta分析显示,卒中急性期、亚急性期及恢复期患者符合失眠障碍诊断标准的比例分别为32.5%、34.8%和37.1%。卒中后失眠不仅增加了卒中死亡及复发风险,而且对卒中康复与预后造成不利影响。本文对卒中后失眠的发病情况、发病机制及治疗等进行综述,以便为临床实践提供信息,并为卒中后失眠提供针对性干预治疗措施。 Abstract: Post stroke ...
杨行妹, 韩美荣, 蒋雪龙, 何忠明, 韩芳
doaj   +1 more source

总胆固醇/高密度脂蛋白胆固醇比值与缺血性卒中复发关系研究 Correlation between Total Cholesterol / High Density Lipoprotein Cholesterol Ratio and Recurrent Stroke in Patients with Acute Ischemic Stroke

open access: yesZhongguo cuzhong zazhi, 2019
【摘要】 目的 探讨急性缺血性卒中90 d内复发与TC/HDL-C比值的关系。 方法 利用急性缺血性卒中患者氧化应激水平临床观察研究(Study on Oxidative Stress in Patients with Acute Ischemic Stroke,SOS-Stroke)数据库的3605例患者作为研究对象,采用多因素Logistic回归分析急性缺血性卒中患者90 d卒中复发的影响因素。 结果 该研究人群中有231例(6.40%)患者90 d卒中复发 ...
王林玉,韩坤强,管生,李振东
doaj   +1 more source

Understanding adherence to continuous positive airway pressure in patients with obstructive sleep apnea post‐stroke: A prospective study based on the Andersen model

open access: yesNursing &Health Sciences, Volume 26, Issue 2, June 2024.
Abstract Adherence to continuous positive airway pressure (CPAP) in patients with obstructive sleep apnea (OSA) post‐stroke is often problematic, despite potential benefits. This study aimed to evaluate CPAP adherence in patients with OSA post‐stroke based on the Andersen behavioral model of health services utilization.
Hua‐Lu Yang   +5 more
wiley   +1 more source

英国国家卒中临床指南2023版要点及解读——缺血性卒中 Interpretation of the Keypoints and Updates on National Clinical Guideline for Stroke for the United Kingdom and Ireland (Edition 2023) —Ischemic Stroke

open access: yesZhongguo cuzhong zazhi, 2023
缺血性卒中的急性期治疗一直是备受关注的话题。英国国家卒中临床指南2016版推出7年来,急性缺血性卒中患者的再灌注已经有了很大的治疗进展以及研究突破,基于这些进展,英国国家卒中临床指南2023版在2016版的基础上,对缺血性卒中的急性期治疗方案进行了部分推荐意见的更新。本文对2023版指南的更新要点进行解读,并与2019年出版的美国心脏学会/美国卒中学会急性缺血性卒中早期管理指南及2023年出版的《中国脑血管病临床管理指南(第2版)》中的推荐进行了对比。 Abstract: The treatment ...
郝曼均1,曹智鑫1,李光硕1,熊云云1,2,3
doaj   +1 more source

Early Symptom Measurement of Post‐Stroke Depression: Development and validation of a new short version 卒中后抑郁的早期症状测量:一个新的短版本的开发和验证

open access: yesJournal of Advanced Nursing, Volume 75, Issue 2, Page 482-493, February 2019., 2019
Abstract Aims The aim of this study was to develop and test the psychometric properties of the Early Symptom Measurement of Post‐Stroke Depression‐Short Form (ESMPSD‐SF). Background The ESMPSD is a specific measurement tool designed to detect early depressive symptoms in acute stroke patients, but it is too long for use in busy clinical settings ...
Jufang Li, Yun Li, Ping Li, Maiyun Ye
wiley   +1 more source

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