Results 111 to 120 of about 8,446 (167)

苯二氮卓受体的提纯及受体亚基单克隆抗体的制备

Zhongshan Daxue xuebao. Yixue kexue ban, 1995
用不实验室建立的亲和层析系统成功地址猪脑分离纯化了苯二氮卓受体（ＢＺ－Ｒ）。结合试验显示，纯化的ＢＺ－Ｒ和专一配基最大的结合容量为１９７０ｆｍｏｌ／ｍｇ蛋白，解离常数Ｋｄ值为５．７ｌｎｍｏｌ／Ｌ，圆盘电泳和等电聚焦电泳均显示出单一区带。纯化受体经ＳＤＳ一聚丙烯酰胺不连续电泳，可分离出分子量分别为５９ｋｕ、５６ｋｕ、５１ｋｕ、４８ｋｕ和３８ｋｕ的５条区带。用这些区带蛋白免疫动物，得到了３种单克隆抗体，酶联免疫检测显示，它们和纯化受体结合的最大滴度分别为１：３００００，１：２２０００，１：２２０００ ...
doaj  

[Expert consensus on monoclonal antibody immunoprophylaxis against respiratory syncytial virus in infants and young children in tropical and subtropical regions of China]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Subspecialty Group of Neonatology, Society of Pediatrics, Chinese Medical Association, Guangdong Medical Association, Editorial Board of Chinese Journal of Contemporary Pediatrics.   +4 more
europepmc   +1 more source

[IgA vasculitis with necrosis of the small intestine secondary to monoclonal gammopathy of renal significance: A case report]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Ding Y, Li C, Huang W, Zhu L, Wang L, Ma D, Zhang J, Shi L.   +7 more
europepmc   +1 more source

Olig2⁺ single-colony-derived cranial bone-marrow mesenchymal stem cells achieve improved regeneration in a cuprizone-induced demyelination mouse model. [PDF]

J Zhejiang Univ Sci B
Peng D, Lu R, Lü L, Yao Q, Yang K, Xu Y, Feng X, Pan R, Ma Y.   +8 more
europepmc   +1 more source

131I-Anti-c-erb2 免疫导向治疗卵巢癌的实验研究

Zhongshan Daxue xuebao. Yixue kexue ban, 2004
【目的】观察放射性核素标记针对癌蛋白为靶点的单克隆抗体载体外对卵巢癌细胞的抑制作用。【方法】应用氯胺T法将131I和抗c-erb2单克隆抗体标记,取不同浓度的131I-Anti-c-erb2与SKOV3细胞共同培养,MTT法检测其对SKOV3细胞生长的抑制作用。【结果】体外单抗浓度为22.20mg/L时,131I-Anti-c-erb2的相对抑制率为64.85%,可以明显抑制SKOV3细胞,未标记的抗c-erb2单抗的相对抑制率为3.40%,对SKOV3细胞的生长几乎没有抑制作用。【结论】131I ...
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3A1-柔红霉素对急性T细胞白血病的效果与安全性初探

Zhongshan Daxue xuebao. Yixue kexue ban, 1996
应用单克隆抗体３Ａ１－柔红霉素结合物（３Ａ１－ＤＭ）临床治疗８例急性Ｔ淋巴细胞白血病患者。经初步验证，鼠源性单克隆抗体制备的导向药物输入人体内未发生严重过敏反应与毒副作用。疗程完毕后，以骨髓象为标准评价临床治疗效果，获完全缓解者３／８例（３７．５％），部分缓解４／８例（５０％），无效１／８例（１２．５％）例，总有效率达８７．５％。初步验证了微量导向药物在临床治疗中的效果。
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[High-throughput sequencing in identifying somatic hypermutation in immunoglobulin heavy chain variable regions with complex clonal backgrounds]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Gao MG, Wei R, Liu Y, Huang XJ, Yang SM, Zhao XS.   +5 more
europepmc   +1 more source

[Chronic myelomonocytic leukemia complicated with T-lymphoblastic lymphoma: a case report and literature review]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Yang YZ, Xu WY, Jiao YJ, Guo ZX.
europepmc   +1 more source

[Rapid screening of single guide RNA targeting pig genome and the harvesting of monoclonal cells by microarray seal]. [PDF]

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi, 2021
Gao M, Zhu X, Wang S, Zhang B, Zhang Y, He Y, Zhou Y, Li S, Yang G, Liao G, Bao J, Bu H.   +11 more
europepmc   +1 more source

[PINK1 suppresses colorectal cancer cell growth through epigenetic regulation of histone modifications]. [PDF]

Zhejiang Da Xue Xue Bao Yi Xue Ban
Wang M, Luan S, Fan X, Han D, Zhu Y.
europepmc   +1 more source