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Zhongshan Daxue xuebao. Yixue kexue ban, 1992 用抗补体免疫荧光法检测鼻咽癌患者和对照人群中EB病毒核抗原-1(EBNA-1)和EB病毒核抗原-2(EBNA-2)抗体的水平。鼻咽癌组中两种抗体滴度都升高,以EBNA-1抗体上升明显;且EBNA-1抗体与总EBNA抗体水平的变化趋势相一致。鼻咽增生性病变组中EBNA-2抗体略占优势,该组中EBNA-2抗体水平升高可能与潜伏状态的EB病毒激活或再感染的早期阶段有关。
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Rare Metals, Volume 45, Issue 7, July 2026.ABSTRACT Tumor metastasis and recurrence are major reasons for the difficulty in curing cancer. Although some immunotherapy methods have been developed, they are still limited by immunosuppression, resulting in limited therapeutic efficacy against tumors.
Chen Ye +4 more
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抗体のN末端特異的蛍光標識による新規抗原検出法の開発 [PDF]
, 2018 本研究では、既存のIgG抗体のN末端を特異的に蛍光標識することで、蛍光応答性抗体を作製する新規手法を開発した。弱酸性条件下で蛍光標識アルデヒドをIgG抗体と反応させることで、N末端特異的に蛍光基が付加され、得られたN末端蛍光標識抗体は、抗原の結合に伴って蛍光強度変化を示すことを明らかにした。また、FRETと蛍光消光解消を組み合わせることで、抗原を蛍光強度比の変化として検出可能な二重標識蛍光応答性抗体を合成すること、および、タグ化タンパク質の無細胞翻訳系での発現をリアルタイム検出することも可能であった ...
芳坂, 貴弘
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Rare Metals, Volume 45, Issue 7, July 2026.ABSTRACT Deep skin infections and dense biofilm barriers caused by Propionibacterium acnes (P. acnes) remain significant challenges in recurrent acne vulgaris, exacerbated by the poor stratum corneum penetration of conventional therapies and rising antibiotic resistance.
Bingran Qi +3 more
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Rare Metals, Volume 45, Issue 6, June 2026.ABSTRACT Directed energy deposition (DED) is an effective method to process complex components with high efficiency, owing to its significant advantage of material saving and features of microarea metallurgy and rapid solidification. This study presents a nano‐Ta‐optimized Ti‐45Al‐8Nb (at%)‐based alloy synthesized via DED. The prepared TiAl‐based alloy
Yi Song +8 more
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Rare Metals, Volume 45, Issue 6, June 2026.ABSTRACT VO2 is a promising thermochromic material, but it is still limited by low transparency, weak solar modulation, and poor stability. Here, we develop a coordination‐compound‐derived strategy to construct a hierarchical BiVO4/VO2@BiVO4 film with a core–shell@nanosheet structure.
Huiyan Xu +11 more
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Rare Metals, Volume 45, Issue 6, June 2026.ABSTRACT To address the demand for high‐temperature stability, broadband strong absorption, and multifunctional integration of electromagnetic wave absorbing materials in complex service environments, lightweight molybdenum disulfide (MoS2) decorated silicon carbide (SiC) nanofiber composite aerogels with a directional layered interconnected structure ...
Zhi Song +4 more
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Zhongguo shiyan zhenduanxue, 2007 目的探讨抗核小体抗体（AnuA）,抗C1q抗体和抗dsDNA抗体与系统性红斑狼疮（Systemic lupus erythemato-sus,SLE）活动性的关系。方法对33例狼疮肾炎（L nephritis,LN）患者血清进行检测抗核小体抗体,抗Clq抗体,抗ds-DNA抗体,以43例无肾炎临床表现的SLE患者做为对照组。同时将76例SLE患者按SLEDAI评分分为SLEDAI ...
金卫东 +3 more
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Rare Metals, Volume 45, Issue 6, June 2026.ABSTRACT Bone restoration is often hindered by the spatiotemporal dysregulation of immune and regenerative signals. Conventional bio‐inert implants, providing only passive support, fail to modulate this microenvironment, leading to infections and poor healing.
Zhizhong Sun +8 more
wiley +1 more source
一步免疫印迹法同时检测抗RA33抗体和抗ENA抗体及其对RA患人的诊断价值
Zhongguo shiyan zhenduanxue, 2005 目的提高抗RA33抗体诊断类风湿性关节炎（RA）的特异性。方法建立一步免疫印迹法,可同时检测抗RA33抗体和抗ENA抗体。并对266例不同风湿性疾病患者血清和24例正常人血清进行了检测。结果抗RA33抗体阳性率:RA 38%（38/100）,SLE 35.8%（24/67）,MCTD 36.4%（8/22）,SS 8.3%（3/36）。抗RA33抗体阳性血清中抗ENA抗体的检出率:95.8%（23/24）SLE有抗Sm/u1RNP抗体,100%（8/8）MCTD有抗u1RNP抗体,100%（3/3 ...
刘学明 +5 more
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