Results 31 to 40 of about 548,061 (167)

间接免疫荧光法检测AchR抗体、MuSK抗体和LRP4抗体在重症肌无力诊断中的价值

open access: yesZhongguo shiyan zhenduanxue, 2021
目的探究与酶联免疫吸附法相比,间接免疫荧光法检测血清AchR抗体、MuSK抗体和LRP4抗体在重症肌无力诊断中的价值。方法本研究招募104例重症肌无力(MG)患者,随机分为两组,分别使用ELISA和间接免疫荧光法检测受试者的血清AchR抗体、MuSK抗体和LRP4抗体水平,分析两种检测方法的阳性检出率、特异性和敏感性,并使用ROC曲线分析间接免疫荧光法用于检测MG的诊断价值。结果ROC分析结果显示IIF法优于ELISA法,IIF法抗体联合诊断MG的曲线下面积为0.938,95%可信区间为0.899-0 ...
邹玲莉, 蔡定军, 陈学波
doaj  

An Ultrasound‐Triggered Antibacterial Hydrogel With Integrated Antioxidant and Angiogenic Functions for Infected Wound Care

open access: yesRare Metals, Volume 45, Issue 5, May 2026.
ABSTRACT Managing diabetic wounds requires simultaneously addressing their infectious, oxidative, and regenerative impairments. To address this, this study integrates a piezoelectric BiOCl@CuSe heterojunction (PFM‐verified) into an injectable F127/HA hydrogel, creating an ultrasound‐responsive smart dressing.
Jiayan Guo   +5 more
wiley   +1 more source

结核病感染状况与抗体特征研究

open access: yesZhongguo shiyan zhenduanxue, 2007
目的调查活动性结核病和稳定期结核病抗体特征。方法采用ELISA或免疫层析技术,检测活动性肺结核、稳定期肺结核和健康人组血清中抗BCG-PPD、抗结核菌胞内蛋白(IP)、胞壁蛋白(CWP)、分泌蛋白(SP)3、8 kD蛋白和LAM抗原的抗体。结果抗38 kD蛋白抗体、抗LAM抗体与结核活动性密切相关。抗CWP抗体阳性患者化疗效果好。结论抗LAM和抗38 kD蛋白抗体为活动性结核病特征性抗体,CWP组分中含有保护性抗原。
董梅   +5 more
doaj  

Metal‐Doped Carbon‐Based Nanomaterials: Photothermal Mechanism Innovation and Precision Therapy Advancement in Antibacterial and Antitumor Applications

open access: yesRare Metals, Volume 45, Issue 5, May 2026.
ABSTRACT Metal‐doped carbon‐based nanomaterials (M‐CNM) play a strategically significant role in next‐generation precision antibacterial and antitumor therapies, as they integrate synergistic photothermal ablation, catalytic reactive oxygen species (ROS) generation, and multimodal imaging capabilities. However, their clinical translation is hindered by
Pengxiang Liu   +5 more
wiley   +1 more source

正常O型人血清ABO血型抗体主要类别的分析

open access: yesZhongguo shiyan zhenduanxue, 2013
目的通过检测O型及A/B型人血清中IgM类及IgG类抗体的效价,分析正常O型人血清中ABO血型抗体的主要类别。方法分别以盐水介质法和间接抗人球蛋白法检测O型及A/B型人血清中IgM类和IgG类抗A或抗B抗体的效价。结果 O型人血清中IgM类抗A/抗B抗体效价均显著高于IgG类抗A/抗B抗体(均P0.05),而IgG类抗A/抗B抗体效价显著高于B/A型人 ...
杨梦娇   +7 more
doaj  

A Dual Co‐Reactant Accelerator Based On Nanoreactor‐Encapsulated CeO2 Nanozymes to Drive Potentiated Luminol Cathodic Electrochemiluminescence for Ultrasensitive Immunoassay

open access: yesRare Metals, Volume 45, Issue 5, May 2026.
ABSTRACT The precise quantification of cytokines is crucial for monitoring disease onset and progression. Herein, we developed a synergistic signal amplification approach by utilizing nanoreactor‐encapsulated CeO2 nanozymes, which were in situ electrodeposited within the mesoporous silica nanochannel film (SNF) grown on indium tin oxide (ITO ...
Yu Cui   +4 more
wiley   +1 more source

一种抗对虾白斑综合症病毒(WSSV)线性抗原表位单链抗体的筛选

open access: yes, 2008
对虾白斑综合症病毒(WSSV)是全世界对虾养殖业最主要的病原体之一,虽然对该病毒的研究已较为深入,但目前仍无有效的防治方法。本研究应用噬菌体展示技术,构建了抗变性WSSV的单链抗体噬菌体展示文库,分别以WSSV病毒粒子和原核表达的囊膜蛋白VP28为靶分子对该文库进行淘选。经过数轮淘选后,得到5个能特异识别WSSV的单链抗体,且首次获得了能特异识别WSSV线性抗原表位的单链抗体P75E8。并通过免疫胶体金电镜分析,对5种单链抗体对应在病毒粒子上的表位进行了定位 ...
戴和平   +4 more
core  

抗Sm抗体对狼疮性肾炎的临床意义 附视频

open access: yesZhongguo shiyan zhenduanxue, 1997
将130例狼疮性肾炎(LN)分为两组,组A抗Sm及抗ds-DNA抗体均阳性,组B仅抗ds-DNA抗体阳性。通过对两组年龄、性别、病程、临床症状、血液学及免疫学预后的比较,分析抗Sm抗体在LN的临床意义,结果发现:①抗Sm抗体与疾病活跃程度相关,可作为判断病情、监测治疗的血清学指标;②抗Sm抗体阳性常伴内脏病变发生率高以及皮肤损害严重,易脱发;③抗Sm抗体为标记性抗体 ...
朱仕荣, 孙林, 叶任高
doaj  

Temperature‐Induced Transformation of Oxidation Mechanism in HfZrTiTa0.5Al0.5 Refractory High‐Entropy Alloy: The Role of Elemental Segregation and Lattice Defects

open access: yesRare Metals, Volume 45, Issue 5, May 2026.
ABSTRACT Refractory high‐entropy alloys (RHEAs) face severe oxidation challenges at elevated temperatures, despite their outstanding mechanical properties. Consequently, understanding the oxidation mechanisms of RHEAs is crucial for their high‐temperature applications.
Zheng Tian   +7 more
wiley   +1 more source

作用力对TNF-α抗原/抗体二维反应的影响

open access: yes, 2003
本文研究了作用力对TNF-α抗原/抗体二维反应的影响,结果表明,TNF-α抗原/抗体间的解离力满足正态分布,而非定值,且不同的作用力,回拉速率和接触时间影响抗原 ...
李宝霞, 龙勉, 叶志义
core  

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