Results 1 to 10 of about 10,277 (165)
Clinical research on progress of antinuclear antibody in rheumatoid arthritis [PDF]
, 2023 Rheumatoid arthritis (RA) is a common chronic, systemic autoimmune disease characterized by erosive arthritis, with a global prevalence of 0.25% to 1.00%, which may ultimately lead to joint deformity and loss of function.
LI Yuan, ZHANG Le, YIN Hanlin, ZHENG Bing, LÜ Liangjing
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Expression and clinical significance of serum complement and IL-25 in systemic lupus erythematosus [PDF]
, 2022 Objective To determine the differences in the expression of serum complement （C） and IL-25 in systemic lupus erythematosus （SLE） involved with single or multi-organ systems， and analyze the correlation between serum C3， C4， CH50， IL-25， C-reactive ...
Wang Yang, Luo Yuhong, Liao Yuan
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Beyond conventional care : developing novel therapeutic approaches to combat arthritis [PDF]
, 2023 Rheumatoid arthritis (RA) is an autoimmune disorder without a definitive cure. Although RA is driven by systemic autoimmunity, its most pronounced manifestation is organspecific inflammation, particularly synovitis in joints.
Xu, Zhongwei
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Zhongguo shiyan zhenduanxue, 2021 目的筛查与肝癌(HCC)相关的自身抗体并对其诊断肝癌的临床价值进行初步评估。方法制备用于自身抗体多重检测的液相芯片,对40例肝炎、32例肝硬化、48例肝癌及30例健康对照组血清进行检测,比较自身抗体IgG水平,筛选与肝癌相关的自身抗体,绘制ROC曲线评估其肝癌的诊断价值,并分析肝癌相关自身抗体与常见生化指标的相关性。结果肝炎、肝硬化、肝癌组的SSA/Ro、tTG、LC1、PR3、Scl-70、Mi-2、MPO和TIF1-γ自身抗体水平均显著高于正常对照组 ...
肖静 +8 more
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Evaluation of medication treatment for Alzheimer's disease on clinical evidence [PDF]
, 2014 Objective To formulate the best treatment plan for Alzheimer's disease patients by evaluating the therapeutic efficacy and side effect of various evidence-based programs.
Ling LIU +3 more
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Zhongguo shiyan zhenduanxue, 2023 目的 探究肿瘤相关抗原(TAAs)LAMR1、ENO1自身抗体在非小细胞肺癌(NSCLC)早期诊断中的价值。方法 收集220例NSCLC患者和220例健康对照者血清，用ELISA方法检测血清中LAMR1、ENO1自身抗体，分析TAAs自身抗体及联合检测的诊断价值。结果 NSCLC患者血清中LAMR1、ENO1自身抗体水平上调 ...
刘欣桐 +5 more
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Clinical analysis of rituximab for adult refractory primary membranous nephropathy [PDF]
, 2023 Objective·To evaluate clinical efficacy and safety of rituximab (RTX) in the patients with refractory primary membranous nephropathy (PMN).Methods·A retrospective analysis was carried out on the patients with refractory PMN, who had recurred or had not ...
BAI Shoujun +4 more
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A Novel Method for Detecting p53 Autoantibodies in Sera of Patients with NSCLC [PDF]
, 2009 Background and objective Serum autoantibody detection is useful means for the early diagnosis and prognosis of cancer. So our objective was to synthesize peptide array to analyse p53 autoantibodies in the sera of patients with non small cell lung cancer (
Kai TANG +4 more
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, 2000 研究背景许多肿瘤患者体内存在自身抗体但其意义尚不清楚自身抗体自身免疫 疾病肿瘤的相互关系值得深入研究 研究目的实验试图通过研究肿瘤患者体内自身抗体的反应模式与肿瘤抗原相关的自 身抗体以及经典自身免疫疾病抗原相关的自身抗体间的相互关系探讨自身抗体在肿瘤中的 意义 材料方法以未伴有自身免疫疾病的食道癌胃癌直肠癌肝癌和肺癌患者血清为研 究对象以人肝癌SMMC-7721细胞蛋白为抗原通过Westernblot技术研究血清中与肿瘤 抗原相关的自身抗体的反应模式采用间接免疫荧光法分析血清中与肿瘤抗原相关的自身 ...
柳珑
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Research of diagnostic biomarkers in Breast cancer and Gastric cancer [PDF]
, 2013 自生物标志物（biomarker）这一概念提出以来，肿瘤生物标志物（tumorbiomarker，TBM）在基础医学领域的研究已成为热点。本文基于大量的临床病理样本，利用免疫组织化学、甲基化芯片分析、实时荧光定量PCR等技术，研究乳腺癌、胃癌预后诊断的生物标志物，为疾病的治疗提供新的思路和靶点。 我们利用免疫组织化学，调查了酪氨酸磷酸酶Shp2和它的伴侣蛋白Gab2在141例乳腺浸润性导管癌中的表达，并分析了他们与临床病理学特征的相关性，发现Gab2蛋白表达与病人的年龄存在显著相关性 ...
陈宝珍
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