Results 31 to 40 of about 13,210 (203)
Abstract The European Union was hit by the financial crisis of 2008. The impact of this crisis, however, and the extent to which this has led to strengthening environmental, health and safety risk regulation in the EU remain open to debate. This article advances the discussion of the “ratcheting‐up” hypothesis by adding a new explanatory factor, namely
Ronit Justo‐Hanani
wiley +1 more source
A Prospective Randomized Study of the Radiotherapy Volume for Limited-stage Small Cell Lung Cancer: A Preliminary Report [PDF]
Background and objective Controversies exists with regard to target volumes as far as thoracic radiotherapy (TRT) is concerned in the multimodality treatment for limited-stage small cell lung cancer (LSCLC).
Fenghua WANG +16 more
core
Prediction of pre‐eclampsia using maternal hemodynamic parameters at 12 + 0 to 15 + 6 weeks
ABSTRACT Objectives To compare the maternal hemodynamic profile at 12 + 0 to 15 + 6 weeks' gestation in women who subsequently developed pre‐eclampsia (PE) and those who did not, and to assess the screening performance of maternal hemodynamic parameters for PE in combination with the Fetal Medicine Foundation (FMF) triple test, including maternal ...
X. Wang +9 more
wiley +1 more source
目的探讨影响非产后出血孕妇分娩后出血量的危险因素。方法随机抽取389例正常分娩的产妇,按新生儿出生体重、妊娠胎数、分娩方式、第三产程时间、人工流产病史等因素分组,进行秩和检验比较产后24小时出血量;并对具有不同个数以上危险因素的产妇组进行秩和检验比较,分析其对产后出血量的影响。结果(1)巨大儿组较非巨大儿组、双胎组较单胎组、手术助产组较自然产组产后24小时出血量多 ...
李囡, 王宏, 王淼
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Linking extinction risk to the economic and nutritional value of sharks in small‐scale fisheries
Abstract To achieve sustainable shark fisheries, it is key to understand not only the biological drivers and environmental consequences of overfishing, but also the social and economic drivers of fisher behavior. The extinction risk of sharks is highest in coastal tropical waters, where small‐scale fisheries are most prevalent.
Andrew J. Temple +7 more
wiley +1 more source
IVF/ICSI-ET妊娠周期中迟发性中重度OHSS的危险因素
目的在接受体外受精/胞浆内单精子注射-胚胎移植(IVF/ICSI-ET)治疗并取得妊娠的周期中,特别是在10~20个获卵数的“magic”范围内,确定迟发性中重度卵巢过度刺激综合征(OHSS)的危险因素。方法采用回顾性队列研究方法,对2017年12月至2018年12月在广州医科大学附属第三医院接受IVF或ICSI-ET的1 386例妊娠周期资料进行分析。对发生迟发性中重度OHSS的患者数据与其他妊娠周期数据进行对比,采用单因素方差分析和卡方检验计算两组的差异 ...
王慧慧, 邓颖, 马倩莹
doaj
FBW7α inhibits the proliferation of CCA cells by decreasing the protein expression of c-myc and cyclinE [PDF]
胆管癌(Cholangiocarcinoma,CCA)是仅次于肝细胞癌的第二大肝脏常见恶性肿瘤,预后差,胆管癌患者的五年生存率仅为5%,而且,近年来其发病率和死亡率呈逐年上升趋势,但是目前对胆管癌发生发展机制的研究还不够深入。 FBW7α(F-boxandWDrepeatdomain-containing7)是一种E3泛素连接酶,可以通过介导底物蛋白的泛素化降解而调控细胞增殖、分化、凋亡、基因组稳定性等细胞进程。FBW7α是一种肿瘤抑制蛋白,在很多肿瘤中发现FBW7的表达减少或者功能缺失,其中 ...
向丹
core
ABSTRACT Objectives Our aim was to examine the prenatal profiles of pregnancies affected by an atypical chromosomal aberration, focusing on pathogenic copy‐number variants (pCNVs). We also wanted to quantify the performance of combined first‐trimester screening (cFTS) and a second‐trimester anomaly scan in detecting these aberrations. Finally, we aimed
K. Gadsbøll +6 more
wiley +1 more source
目的了解侵袭性肺炎链球菌(Streptococcus pneumonia,Spn)感染现状及其危险因素,为有效预防和控制侵袭性Spn感染提供参考资料。方法回顾性调查我院侵袭性Spn感染病例资料,采用病例对照研究方法,对侵袭性Spn感染的相关因素进行单因素分析和多因素非条件logistic回归分析,确定危险因素。结果 43例侵袭性Spn感染患者,血液感染占86.0%,中枢神经系统及胸、腹腔感染占14.0 ...
王倩, 曹玙, 吴桐
doaj
Protein phosphatase 2A-B55δ enhances chemotherapy sensitivity of human hepatocellular carcinoma under the regulation of microRNA-133b [PDF]
目的:原发性肝细胞癌(hepatocellularcarcinoma,HCC)是我国公共卫生关注的热点问题之一,寻找增强HCC化疗敏感性的有效干预靶点具有重要意义。蛋白磷酸酶2A(proteinphosphatase2A,PP2A)是重要的肿瘤抑制因子;PPP2R2D基因编码的PP2A-B55δ亚基参与细胞周期有丝分裂调控。我们前期研究验证了PPP2R2D基因3’-非翻译区(3’-untranslatedregion,3’UTR)的+15G>C多态性位点受微小RNA-133b(microRNA-133b,
庄群瑛
core

