A new paradigm of genetic testing for hereditary breast/ovarian cancers [PDF]
, 2016 INTRODUCTION: Genetic risk factors and family history play an important role in breast cancer development. This review aimed to summarise the current genetic testing approach to hereditary breast/ovarian cancer.
Chen, J, Kwong, A, Shin, VY
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Research progress of the role of non-canonical Wnt signaling pathway in ovarian cancer and its potential therapeutic implications [PDF]
, 2023 Ovarian cancer is a malignant tumor of the female reproductive system with the highest mortality, and involves the aberrant regulation of multiple molecular signaling pathways.
TENG Yincheng, ZHOU Wanzhen
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Ovarian Cancer in China：Trends in Incidence and Mortality，2005—2016 [PDF]
, 2022 BackgroundThe health impairment caused by ovarian cancer in female population has become a global focus. However, there is a lack of research on ovarian cancer incidence and mortality trends in Chinese female population.ObjectiveTo describe the trends of
HUANG Haitao, CHEN Shuyu, GENG Xu, WAN Xiao, JIA Ruiying, LIANG Dandan, CHEN Chaoran
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Expression levels of TTF-1 and CyclinD1 and their relationship with lymphangiogenesis in ovarian cancer [PDF]
, 2023 Objective To investigate the expression levels of thyroid transcription factor-1 （TTF-1） and CyclinD1 in ovarian cancer and analyze their relationship with lymphangiogenesis.
Zhang Xin, Yan Qianwen, Wang Luyi
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Study on the diagnostic efficacy of ADNEX model in differentiating metastatic and primary ovarian cancer [PDF]
, 2023 Objective: To study the clinical value of the International Ovarian Tumor Analysis(IOTA) ADNEX(the Assessment of Differential NEopasia in the adneXa) model in differentiating metastatic ovarian cancer from primary ovarian cancer.
NI Zhongxin, CHEN Hui
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The latest progress and prospect of gynecological tumor treatment at 2023 ESMO [PDF]
, 2023 Many major research achievements have been made in the past year in the field of gynecologic oncology (cervical cancer, ovarian cancer and endometrial cancer), including surgical treatment, local advanced treatment mode and exploration of new treatments ...
XIA Lingfang, ZHU Jun, WU Xiaohua
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Review of role of fatty acid binding protein-4 in obesity-associated tumors [PDF]
, 2023 Obesity is one of the major factors threatening human health. Excessive fat accumulation not only has detrimental effects on human metabolism and cardiovascular system, but also is highly correlated to the incidence and mortality of various tumors. Fatty
FENG Ming, MENG Jian, WU Ruifang
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Expert consensus on genetic counseling in gynecological oncology (2023 edition) [PDF]
, 2023 With the increasing applications of high-throughput genome sequencing technology, there is a growing recognition of the important roles of genetic factors in the occurrence and development of gynecological tumors.
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Current status and influencing factors of gene screening in first-degree relatives of patients with hereditary breast-ovarian cancer syndrome [PDF]
, 2023 Background and purpose: Carriers of BRCA1/2 gene germline mutations have an increased lifetime risk of ovarian, breast and other cancers. Early identification of these high-risk groups and targeted risk management programs are important for reducing ...
WANG Hui, WANG Xia, GAO Yi, XU Jing, YU Xiaojuan, FAN Fangqin, DING Yan, KANG Yu
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ARHI interacts with TR3 and activates apoptosis and autophagy via mitochondrial signaling pathway in human gastric cancer cells [PDF]
, 2015 ARHI是一个母源性抑癌印记基因，属ras/rap超家族成员，在人类多种正常组织中高表达，而在人卵巢癌、乳腺癌、胰腺癌、肝癌等多种肿瘤中表达明显下调或缺失。ARHI可以调节细胞周期控制细胞增殖，并通过多种途径参与细胞的凋亡和自噬。核孤儿受体TR3属于类固醇/甲状腺受体超家族，几乎参与人体所有组织和器官的功能调节。TR3作为转录因子调控基因表达，参与细胞增殖和凋亡调控过程，还可以作为功能蛋白，通过蛋白亚细胞定位、蛋白相互作用和蛋白修饰等途径发挥作用。本课题研究两个蛋白是否结合及其结合模式 ...
徐伟
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