卵巢癌患者血清ROMA、CA125、HE4联合检测的临床意义
卵巢癌是女性生殖系统恶性肿瘤,晚期患者5年生存率较低,预后较差[1]。目前卵巢癌的辅助诊断血清学指标常用糖类抗原125(CA125)[2],附睾蛋白4(HE4)是临床常用的另一种辅助的诊断肿瘤标记物,具有较高的特异性和敏感性[3]。卵巢恶性肿瘤风险预测值(ROMA)是近年来临床提出的一种新的预测卵巢癌的指标 ...
孔琪
doaj
卵巢肿瘤组织类型复杂,卵巢癌肉瘤极为罕见。根据WHO制定的女性生殖系统肿瘤组织学分类(2014版),上皮性肿瘤占卵巢恶性肿瘤的85%~90%,高级别浆液性癌作为Ⅱ型卵巢上皮性癌,肿瘤生长迅速,预后不良。卵巢癌肉瘤为恶性混合性中胚层肿瘤中的一种,组织中含有恶性上皮成分及肉瘤成分。本文结合吉林大学中日联谊医院妇科收治1名卵巢高级别浆液性癌局部肉瘤样癌分化患者,提高对该疾病的认识及探索治疗上的新方法。1 临床资料患者女性 ...
王皓莹, 王雪, 冷维春
doaj
目的研究β2-微球蛋白在卵巢癌患者血液、尿液中的变化。方法选择在我院住院的卵巢癌组患者68例,卵巢良性肿瘤组患者65例,正常卵巢患者组60例。分别在手术前或者检查身体时抽取静脉血和留取尿液。采用免疫透射比浊法检测三组患者血液和尿液中β2-微球蛋白(β2-MG)的水平。比较卵巢癌不同分期、分级患者血/尿β2-MG的变化。结果卵巢癌患者血液中β2-MG(4.87±0.64)和尿液中β2-MG(4.86±0.72)明显高于卵巢良性肿瘤组血液中β2-MG(2.69±0.36)和尿液中β2-MG(2.73±0 ...
徐晓宏, 张伟, 王立新
doaj
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