Results 21 to 30 of about 4,012 (161)

Impact of deep or ovarian endometriosis on pelvic pain and quality of life: prospective cross‐sectional ultrasound study

open access: yesUltrasound in Obstetrics &Gynecology, Volume 65, Issue 3, Page 372-383, March 2025.
ABSTRACT Objective To assess whether premenopausal women diagnosed with deep or ovarian endometriosis on transvaginal sonography (TVS) were more likely to suffer from dyspareunia and pelvic pain symptoms, and have a lower quality of life, compared to women without sonographically diagnosed deep or ovarian endometriosis.
P. Chaggar   +5 more
wiley   +1 more source

Application of artificial intelligence to ultrasound imaging for benign gynecological disorders: systematic review

open access: yesUltrasound in Obstetrics &Gynecology, Volume 65, Issue 3, Page 295-302, March 2025.
ABSTRACT Objective Although artificial intelligence (AI) is increasingly being applied to ultrasound imaging in gynecology, efforts to synthesize the available evidence have been inadequate. The aim of this systematic review was to summarize and evaluate the literature on the role of AI applied to ultrasound imaging in benign gynecological disorders ...
F. Moro   +8 more
wiley   +1 more source

组蛋白去乙酰化酶1在人上皮性卵巢癌组织中的表达

open access: yesZhongguo shiyan zhenduanxue, 2011
目的探讨上皮性卵巢癌组织中组蛋白去乙酰化酶1(HDAC1)的表达及临床意义。方法采用免疫组化SP法,测定40例上皮性卵巢癌组织2、0例交界性卵巢肿瘤,20例卵巢良性肿瘤以及10例正常卵巢组织中HDAC1的表达。结果 HDAC1在在卵巢组织中的阳性表达H-score评分均随组织异型程度的增加而逐渐增高,即正常卵巢组织(1.300±0.948 68)和卵巢良性肿瘤(1.750±0.786 40)
贾妍   +4 more
doaj  

ARHI interacts with TR3 and activates apoptosis and autophagy via mitochondrial signaling pathway in human gastric cancer cells [PDF]

open access: yes, 2015
ARHI是一个母源性抑癌印记基因,属ras/rap超家族成员,在人类多种正常组织中高表达,而在人卵巢癌、乳腺癌、胰腺癌、肝癌等多种肿瘤中表达明显下调或缺失。ARHI可以调节细胞周期控制细胞增殖,并通过多种途径参与细胞的凋亡和自噬。核孤儿受体TR3属于类固醇/甲状腺受体超家族,几乎参与人体所有组织和器官的功能调节。TR3作为转录因子调控基因表达,参与细胞增殖和凋亡调控过程,还可以作为功能蛋白,通过蛋白亚细胞定位、蛋白相互作用和蛋白修饰等途径发挥作用。本课题研究两个蛋白是否结合及其结合模式 ...
徐伟
core  

Clinical utility of ultrasonography in pediatric and adolescent gynecology: retrospective review of 1313 ultrasound examinations

open access: yesUltrasound in Obstetrics &Gynecology, Volume 65, Issue 2, Page 226-234, February 2025.
ABSTRACT Objectives Ultrasound is the first‐line imaging modality of the pelvis in the pediatric and adolescent gynecology (PAG) population. Ultrasound findings in pre‐ and postpubertal PAG patients differ from those in adults. Diagnostic models for adnexal pathology have not been validated in this cohort.
N. Cooper   +15 more
wiley   +1 more source

CA125与HE4联合检测及不同CA125阳性区间在卵巢肿瘤鉴别诊断中的意义

open access: yesZhongguo shiyan zhenduanxue, 2015
卵巢肿瘤是女性常见的妇科肿瘤,其中卵巢上皮性肿瘤最常见,占原发性卵巢肿瘤的50%-70%,包括卵巢良性、交界性及恶性肿瘤。卵巢深居盆腔内,且卵巢肿瘤临床症状多不典型,如何在术前较准确地判断其性质,确定治疗方案,仍是临床医生比较棘手的问题。卵巢交界性肿瘤是一种低度潜在恶性的卵巢肿瘤,占卵巢上皮性肿瘤的10%-15%[1]。卵巢恶性肿瘤的发病率占女性生殖道恶性肿瘤的第三位,且有逐年增高趋势 ...
王华杰   +4 more
doaj  

Hira基因产物在银鲫和彩鲫卵子发生过程中的动态变化 [PDF]

open access: yes, 2010
为进一步研究Hira基因在卵子发生和雌核发育过程中的作用,通过原位杂交和免疫荧光定位的方法检测了Hira mRNA和蛋白质在雌核发育银鲫和两性生殖彩鲫卵子发生过程中的动态变化。结果表明,银鲫和彩鲫卵子发生过程中Hira基因转录产物的变化基本一致,在Ⅰ期卵母细胞的细胞核中大量表达,至Ⅱ期卵母细胞时转至细胞质中均匀分布,在Ⅲ期卵母细胞中,杂交信号逐渐移向细胞的周边,到Ⅳ期时随着卵黄物质大量积累,杂交信号几乎不见。HIRA蛋白在银鲫和彩鲫卵子发生过程中的变化略有差别。HIRA蛋白在银鲫Ⅰ期卵母细胞中没有表达,
桂建芳   +3 more
core  

Evaluating use of two‐step International Ovarian Tumor Analysis strategy to classify adnexal masses identified in pregnancy: pilot study

open access: yesUltrasound in Obstetrics &Gynecology, Volume 64, Issue 6, Page 808-817, December 2024.
ABSTRACT Objectives The primary aim was to validate the International Ovarian Tumor Analysis (IOTA) benign simple descriptors (BDs) followed by the Assessment of Different NEoplasias in the adneXa (ADNEX) model, if BDs cannot be applied, in a two‐step strategy to classify adnexal masses identified during pregnancy. The secondary aim was to describe the
J. Barcroft   +8 more
wiley   +1 more source

人类激肽释放酶基因6在卵巢恶性肿瘤中的表达及其机制研究

open access: yesZhongguo shiyan zhenduanxue, 2014
目的研究人组织激肽释放酶基因6(KLK6)mRNA和蛋白在卵巢肿瘤组织中的表达水平,探讨其在卵巢恶性肿瘤中的作用机制。方法应用RT-PCR和免疫组化SP法分别检测在正常的卵巢组织、卵巢的良性肿瘤、卵巢的交界性肿瘤及卵巢的恶性肿瘤组织中KLK6的mRNA表达及蛋白的表达,探讨该基因的表达与卵巢恶性肿瘤患者的临床病理特征关系。结果本研究显示,在卵巢癌组织中,KLK6mRNA的表达水平与正常卵巢组织相比,显著增高;卵巢癌组织中KLK6蛋白的阳性表达率为69.4%,与正常卵巢组织(13.3%)、良性卵巢肿瘤 ...
成志强   +6 more
doaj  

Ovarian ectopic pregnancy: clinical characteristics, ultrasound diagnosis and management

open access: yesUltrasound in Obstetrics &Gynecology, Volume 63, Issue 6, Page 815-823, June 2024.
ABSTRACT Objective To compare the clinical, ultrasound and biochemical characteristics of ovarian ectopic pregnancy (OEP) with those of tubal ectopic pregnancy (TEP). Methods This was a retrospective case–control study of women with OEP and those with TEP seen at a single center between December 2010 and February 2021.
S. A. Solangon, J. Naftalin, D. Jurkovic
wiley   +1 more source

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