西藏西北地区藏族人群高同型半胱氨酸血症的患病现状与血尿酸血脂的关联性分析 [PDF]
目的为了了解西藏西北地区藏族人群高同型半胱氨酸血症(HHcy)患病现状及其与血脂、血尿酸等的关联,探讨西藏西北地区高同型半胱氨酸血症等慢性病的防治策略。方法本次调查采用多阶段分层整群随机抽样的方法,对西藏西北地区(阿里地区、那曲市)居住6个月以上、18岁及以上的3 432名藏族居民进行了问卷调查、体格检查以及生化检测等。结果西藏西北地区藏族居民HHcy患病率为75.7%,远高于我国平均人群的患病率(37.2%)。血尿酸、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇是HHcy的危险因素 ...
肖若愚, 张玉飞, 熊海
doaj +3 more sources
Correlation between the Polymorphism of Coagulation-Related Genes and Lower Extremity Deep Venous Thrombosis [PDF]
Objective To investigate the correlation between the polymorphism of 4 coagulation-related genes, rs1799963 (coagulation factor V gene Leiden), rs6025 (prothrombin gene G20210A), rs1042579 (thrombomodulin protein gene c.1418C>T) and rs1801131 ...
JIANG Yao-ru, NIU Lei-lei, FENG Na, et al.
core +1 more source
Comparison of Three Risk Prediction Models for Carotid Atherosclerosis in Steelworkers [PDF]
BackgroundAs a leading cause of ischemic cerebrovascular disease, carotid atherosclerosis (CAS) lowers the productivity of steelworkers. An increasing number of scholars have used machine learning to identify readily available factors to predict the risk
WANG Jiaojiao, CHEN Yuanyu, ZHENG Ziwei, YANG Yongzhong, CHEN Zhe, LI Chao, WANG Haidong, WU Jianhui, WANG Guoli
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DNA甲基化与高同型半胱氨酸血症 DNA Methylation and Hyperhomocysteinemia
DNA甲基化是一种调控基因表达的表观遗传机制,由Hcy代谢相关底物S-腺苷同型半胱氨酸(S-adenosyl-L-homocysteine,SAH)依赖性的DNA甲基转移酶(DNA methyltransferases,DNMTs)催化,对维持细胞稳态至关重要。多项研究表明,高同型半胱氨酸血症(hyperhomocysteinemia,HHcy)可能通过调节甲硫氨酸-同型半胱氨酸循环(methionine-homocysteine cycle,M-H cycle)调控DNA甲基化状态 ...
瓮佳旭, 周宏宇, 李子孝
doaj +1 more source
Analysis of Characteristics and Influencing Factors of Hearing Impairment in Patients with Polycystic Ovary Syndrome [PDF]
BackgroundHearing impairment in patients with polycystic ovary syndrome (PCOS) has been confirmed, However, the influencing factors of hearing impairment in PCOS patients have not been fully explained.ObjectiveTo explore the characteristics of hearing ...
XIE Zhijia, ZHANG Lei, CHEN Xin, CHANG Tao
core +1 more source
Investigation and identification of the first mushroom poisoning case caused by Amanita sychnopyramis f. subannulata in Jiangxi [PDF]
Objective To investigate and identify a case caused by mushroom poisoning in May 2019 in Jiangxi Province. Methods The case was studied with the epidemiological information, clinical data, and suspicious mushroom samples were identified by morphological ...
Chengwei LIU +6 more
core +1 more source
Evaluation of Cardiac Structure and Function in Patients with Wilson Disease Based on RT-3DE: a Clinical Study [PDF]
Background Wilson disease (WD) is a rare autosomal recessive disease that causes impaired copper excretion, mainly manifestedashepatic and/or neuropsychiatric symptoms, but diversifies with the varying affected organs and severity of the disease.
ZHANG Yu, WANG Meixia, ZHANG Jing, WANG Fei, LI Zhonglei, ZHANG Yanyun, JIANG Zhenzhen
core +1 more source
亚甲基四氢叶酸还原酶基因多态性及甲状腺功能与妊娠期糖尿病的相关性
目的 探讨亚甲基四氢叶酸还原酶(MTHFR)基因C677T位点多态性及甲状腺功能与妊娠期糖尿病的相关性。方法 选取承德医学院附属医院51名患有妊娠期糖尿病的孕妇作为病例组,同期60名正常妊娠孕妇作为对照组。运用PCR-荧光探针法检测两组的MTHFR C677T基因多态性。采用全自动免疫分析仪进行甲状腺功能指标的测定。应用全自动生化分析仪检测两组研究对象的血浆同型半胱氨酸水平。对比两组孕妇甲状腺功能、同型半胱氨酸和MTHFR基因型分布情况,探讨MTHFR基因多态性及甲状腺功能与妊娠期糖尿病的关系。结果 ...
王玲玲 +4 more
doaj
A Real-world Research of Huoxue Sanfeng Acupuncture Intervention on Blood Pressure in Patients with Cerebral Infarction and Hypertension [PDF]
BackgroundAs the most common chronic disease, hypertension is an important high-risk factor for cardiovascular and cerebrovascular diseases and vascular events.
HE Qiuxia, DU Yuzheng, MENG Xianggang, SHI Xuemin
core +1 more source
血浆同型半胱胺酸和D-二聚体水平与急性期脑梗死各亚型的关系 [PDF]
目的:探讨血浆同型半胱胺酸和D-二聚体在急性期各亚型脑梗死之间的差异,为临床脑梗死亚型的病因学诊断提供理论依据。方法:收集我院246例24 h内发病的脑梗死患者,根据TOAST分型方法进行病因学分型:大动脉粥样硬化性脑卒中(1arge—artery atherosclerosis,LAA;n=66)、小动脉闭塞性脑卒中(small-artery occlusion ,SAO;n=76)、心源性脑栓塞(cardio embolism,CE;n=40)、其他确定原因引发的缺血性脑卒中(stroke of ...
Da-lin YU +6 more
core +3 more sources

