2 型固有免疫细胞在过敏性及非过敏性哮喘中的临床意义 2型固有免疫细胞在过敏性及非过敏性哮喘中的临床意义
【目的】观察过敏性及非过敏性哮喘发病过程中2型固有免疫细胞(ILC2)的差异,探讨ILC2与哮喘临 床评价指标的相关性。【方法】研究对象来自我院2017年6月至2018年1月的过敏性和非过敏性哮喘患者,收集相 应临床基线资料并评估病情、进行血常规、肺功能等检查;应用流式细胞术检测外周血ILC2;通过ELISA和多因子检 测分别测定总IgE及sIgE和Th2型细胞因子。【结果】哮喘(Asthma)组的ILC2比例和计数与嗜酸性粒细胞(EOS)计 数及sIgE 正相关(r=0.37,0.32,0 ...
曾智敏 +6 more
doaj
Efficacy of Huaiqihuang granules as adjuvant therapy for bronchial asthma in children: a real-world study. [PDF]
Wang HM +25 more
europepmc +1 more source
目的测定血清ECP并探讨其在哮喘患者中的临床应用价值。方法使用UniCAP100型自动酶免疫荧光分析系 统测定。结果测定50例正常人,47例缓解期哮喘患者和42例发作期哮喘患者血清ECP平均水平分别为7.42±3.56,14.75± 4.82和35.80±4.55μg/L(x±s),各组间均有明显差异,以发作期患者组ECP升高最为显著(p<0.01)。上述42例发作期哮喘 患者经抗炎治疗后,ECP平均水平为24.66±5.12μg/L,较治疗前明显下降(P<0.01)。结论血清ECP水平反映气道的炎症 ...
陈瑜 +5 more
doaj
[Profiles of IgE sensitization to dust mite allergen components in patients with allergic rhinitis and asthma]. [PDF]
Wang X +6 more
europepmc +1 more source
[Short-term effects and seasonal variation of ozone on daily hospital outpatient visits for childhood asthma in Lanzhou]. [PDF]
Zhang H +5 more
europepmc +1 more source
【目的】 观察气道内T-bet基因转染对哮喘小鼠脾脏淋巴细胞Th1/Th2平衡65380;T-bet及GATA-3 mRNA表达的影响65377; 【方法】 将C57BL/6小鼠32只随机分为4组,每组8只,分别为正常对照组(A组)65380;哮喘模型组(B组)65380;空质粒干预组(C组) 和T-bet质粒干预组(D组)65377;卵白蛋白(OVA) 抗原溶液腹腔注射致敏,滴鼻造模65377;空质粒组和T-bet质粒干预组OVA激发24 h前,分别经鼻滴入50 μg空质粒65380;重组T ...
doaj
[Acupuncture alleviates chronic airway inflammation in obese asthmatic mice by downregulating Vnn1 and FAM126B]. [PDF]
Li X, Ye T, Xi L, Li C, Liu H.
europepmc +1 more source
Application of fractional exhaled nitric oxide and nasal nitric oxide in control evaluation of bronchial asthma and diagnosis of allergic rhinitis in children. [PDF]
Li R +6 more
europepmc +1 more source
[Current status and influencing factors of sleep disorders in school-age children with asthma]. [PDF]
Wei JH, Ju YB.
europepmc +1 more source
Effect of exercise rehabilitation on exercise capacity and quality of life in children with bronchial asthma: a systematic review. [PDF]
Liu F, Liu YR, Liu L.
europepmc +1 more source

