Results 11 to 20 of about 6,209 (198)

Effect of Qufeng Xuanbi Formula on experimental asthma guinea pigs' airway inflammation and Th1/Th2 cytokines [PDF]

open access: diamond, 2014
目的  观察祛风宣痹方对哮喘豚鼠气道炎症和Th1/Th2细胞因子的影响,探讨其作用机制。方法  用卵蛋白和雾化吸入致敏法,复制豚鼠哮喘模型;取肺泡灌洗液进行嗜酸性粒细胞(Eos)计数;肺组织切片HE染色形态学观察;ELASA方法检测BALF中IFN-γ和IL-4的含量。结果  模型组较正常组肺泡灌洗液(BALF)中气道Eos炎症细胞表达异常,组织形态学病变明显,IFN-γ含量显著下降,IL-4的含量明显升高;地塞迷松米组、中药高剂量组、中药低剂量组较模型组均有显著性差异,BALF中Eos的数量明显降低 ...
Shi, Suo-fang, Zhou, Kui-long
core   +3 more sources

呼出气一氧化氮测定与肺功能检测在哮喘病人诊断中的临床应用比较 [PDF]

open access: diamond, 2014
Objective:  Comparison the test result of exhaled nitric oxide (FeNO) level and pulmonary function for the patients with bronchial asthma. We will find the fast、efficient method for early diagnosis of bronchial asthma.
Wu, Xu-wei, Zhang, Yu-feng
core   +3 more sources

广州、湛江、茂名、江门四市部份十七万人口中支气管哮喘流行病学情况的初步调查 [PDF]

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 1987
目前,支气管哮喘(以下简称哮喘)在广东地区的流行病学情况尚无完整的数据。哮喘的患病率可因调查地区,人数,对象,方法和环境因素等不同而相差悬殊。我们于一九八三年四月至一九八四年七月对广州、湛江、茂名、江门四市的部份工厂,学校,街道居民点共172,162人进行了哮喘患病情况的初步调查。
张森泉
doaj   +2 more sources

哮喘合并慢性阻塞性肺疾病患者急性加重期血清CTGF、HIF-1α水平变化及临床意义

open access: greenZhongguo shiyan zhenduanxue
目的分析哮喘合并慢性阻塞性肺疾病(COPD)患者急性加重期血清结缔组织生长因子(CTGF)、缺氧诱导因子(HIF)-1α水平变化,并探究其对患者急性加重期的诊断价值。方法前瞻性选择COPD急性加重期患者(COPD急性组)、哮喘急性发作期患者(哮喘急性组)、哮喘合并COPD急性加重期患者(并发组)、健康体检者(健康组)各86例。检测受检者血清CTGF、HIF-1α水平及肺功能指标,采用Pearson相关性分析CTGF、HIF-1α水平之间及与肺功能指标关系,分析血清CTGF、HIF ...
杨君莉   +4 more
doaj   +1 more source

An application of the Biobehavioral Family Model: Examining the impact of maternal depression on child asthma mediated by insecure attachment and child depression

open access: yesFamily Process, Volume 61, Issue 4, Page 1610-1628, December 2022., 2022
Abstract Objective Child asthma disparities are prevalent in socio‐economically stressed single‐parent families. Stress impacts childhood asthma mediated by immune and autonomic pathways, but specific family stress pathways are not well established. This study tests the hypothesis, derived from a version of the Biobehavioral Family Model, that single ...
JungHa Lim   +2 more
wiley   +1 more source

The value of small airway function parameters and fractional exhaled nitric oxide for predicting positive methacholine challenge test in asthmatics of different ages with FEV1 ≥ 80% predicted

open access: yesClinical and Translational Allergy, Volume 11, Issue 1, March 2021., 2021
Abstract Background Small airway function parameters (SAFPs) combined with fractional exhaled nitric oxide (FeNO) can predict a positive methacholine challenge test (MCT) for asthma diagnosis. However, their predictive utility in patients with forced expiratory volume in one second (FEV1) ≥80% predicted within different age ranges remains unclear. This
Lili Hou   +7 more
wiley   +1 more source

Immunopathogenesis of the feline atopic syndrome

open access: yesVeterinary Dermatology, Volume 32, Issue 1, Page 13-e4, February 2021., 2021
Résumé Contexte Les maladies félines supposées d’origine allergique avec des phénotypes cliniques semblables, peuvent avoir de nombreuses pathogénies différentes sous jacentes. Le phénotype clinque, l’étiologie précise et l’immunopathogénie sous jacente doivent tous être considérés si des avancées veulent être faites dans ces domaines négligés de la ...
Richard Halliwell   +3 more
wiley   +1 more source

Clinical signs and diagnosis of feline atopic syndrome: detailed guidelines for a correct diagnosis

open access: yesVeterinary Dermatology, Volume 32, Issue 1, Page 26-e6, February 2021., 2021
摘要 背景 猫特应性综合征(FAS)涵盖了一系列超敏反应疾病, 以高度多样化的临床表现为特征, 包括皮肤、胃肠道和呼吸系统。这些疾病包括猫特应性皮肤综合征(FASS), 其中超敏反应通常与环境过敏原相关, 尽管食物过敏可能同时存在。也可能累及其他器官系统 (如哮喘)。由于其高度异质性的临床表现, FASS的诊断可能具有挑战性。 目的 国际动物过敏性疾病委员会(ICADA)的一个亚组的任务是总结FASS临床表现的最新信息, 并制定诊断指南。 方法 检索在线引文数据库和国际会议摘要中与猫过敏相关的出版物。必要时结合专家意见。 结果 共找出107篇与本综述相关的出版物。汇编这些资料能够制定FASS临床特征的详细描述和制定指南, 重点是系统性消除具有相似临床特征的其他皮肤疾病 ...
Domenico Santoro   +4 more
wiley   +1 more source

Acupuncture Treatment for Cough‐Variant Asthma: A Meta‐Analysis

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2021, Issue 1, 2021., 2021
Background. In recent years, there have been many clinical reports on acupuncture treatment of cough‐variant asthma, but no researcher has objectively analysed and evaluated the efficacy and safety of acupuncture treatment of cough‐variant asthma from the perspective of evidence‐based medicine. Objective.
Jian Xiong   +8 more
wiley   +1 more source

儿童下气道菌群多样性及其对支气管哮喘辅助性T细胞分化机制影响研究进展 [PDF]

open access: yes, 2018
哮喘是由多种细胞(如嗜酸性粒细胞、肥大细胞、T淋巴细胞、中性粒细胞、气道上皮细胞等)和细胞组分参与的以慢性气道炎症和气道高反应性为特征的一种异质性疾病[1]。近年来哮喘发病率逐年攀升,据全球哮喘防治创议(GINA)委员会调查显示,全球约有3亿人受到哮喘困扰[2],世界卫生组织(WHO)预计至2025年全世界哮喘患者将会增至4亿人。研究发现,哮喘患者气道菌群在丰度及多样性等方面与正常人存在显著差异[3 ...
侯凌云, 吴谨准, 葛丹丹
core   +1 more source

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