MMP-9、TIMP-1及VEGF在大肠癌中的表达与临床病理和预后的相关性研究
目的研究MMP-9、TIMP-1及VEGF在大肠癌组织中的表达与临床病理和预后关系。方法对62例大肠癌患者的手术切除之癌组织和癌周正常组织,应用免疫组织化学方法检测其VEGF、基质金属蛋白酶(MMP-9)和组织金属蛋白酶抑制剂(TIMP-1)的表达情况,探讨这些因子表达与临床病理和预后关系。结果在62例大肠癌肿瘤组织:有29例VEGF表达阳性,阳性率46.8%;41例MMP-9表达阳性,阳性率为66.1%;39例TIMP-1表达阳性,阳性率为62.9%。这三种蛋白的表达水平与组织类型、组织分化程度 ...
康旭, 王芳, 曹军, 冼沛中
doaj
[Whole genome sequencing and analysis of familial nonsyndromic congenital tooth agenesis]. [PDF]
Zheng Y, Wang D, Jiang T, Yang D, Lu H.
europepmc +1 more source
[Preparation of magnetic bifunctional materials for exosome capture from serum and phosphopeptide enrichment]. [PDF]
Wang ZR, Zheng HJ, Jia Q.
europepmc +1 more source
【目的】 对亚洲牛带绦虫钙调神经磷酸酶B基因(CaN)进行克隆65380;表达和免疫学初步研究65377;【方法】 将亚洲牛带绦虫成虫钙调神经磷酸酶B基因克隆到原核表达质粒pET*9鄄30a(+)中,在大肠杆菌BL*9鄄21/DE3中用诱导表达,表达产物通过十二烷基磺酸钠*9鄄聚丙烯酰胺凝胶电泳(SDS*9鄄PAGE)进行鉴定,用镍离子金属螯合剂亲和层析柱进行纯化,纯化的重组蛋白用蛋白印迹进行免疫学分析65377;【结果】 PCR65380;双酶切及DNA测序结果均表明重组质粒pET*9鄄30a ...
doaj
[Clinical and genetic analysis of two families with combined defect in antithrombin and protein C genes]. [PDF]
Guo YL +6 more
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[Tibetan Medicine Classic Formula Srolo Bzhtang Granules Ameliorates Pulmonary Fibrosis via Dual Pathways of Nrf2/HO-1 and PI3K/AKT/mTOR Regulating Oxidative Stress]. [PDF]
DU J +5 more
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[Advances in oral and craniofacial bone regeneration modulated by stem cells and biomaterials]. [PDF]
Li Z +6 more
europepmc +1 more source
[Research progress on the quercetin target role and signaling pathway in anti-liver fibrosis]. [PDF]
Zhao RQ +9 more
europepmc +1 more source
[Application of Kartogenin in cartilage tissue engineering]. [PDF]
Jiang J, Zhang S, Lu W.
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[Research progress on protein lactylation modification in malignant tumors]. [PDF]
Dong H, Chen H, Zhang C.
europepmc +1 more source

