Results 21 to 30 of about 8,610 (146)
Journal of Diabetes, Volume 15, Issue 10, Page 817-837, October 2023., 2023 Highlights Type 2 diabetes mellitus (T2DM) is characterized by progressive loss of beta‐cell function and mass. Numerous mechanisms of beta‐cell failure are involved. Preservation and/or enhancement of beta‐cell function is of great importance in delaying the progression of T2DM and the burden of its complications. Accurate evaluation of the effects of
Laure Sayyed Kassem +3 more
wiley +1 more source
Journal of Diabetes, Volume 15, Issue 10, Page 838-852, October 2023., 2023 Highlights This review outlines the history of miRNA discovery and its major advances in the field of metabolism. We explore the roles of miRNAs in diabetes‐related cognitive impairment. We innovatively propose that miRNAs also act with a certain organ‐targeting specificity due to the organ‐targeting nature of extracellular vesicles, which may aid ...
Yining Chao +5 more
wiley +1 more source
The shape of aroma: Measuring and modeling citrus oil gland distribution
PLANTS, PEOPLE, PLANET, Volume 5, Issue 5, Page 698-711, September 2023., 2023 Citrus are intrinsically connected to human health and culture, preventing human diseases like scurvy and inspiring sacred rituals. Citrus fruits come in a stunning number of different sizes and shapes, ranging from small clementines to oversized pummelos, and fruits display a vast diversity of flavors and aromas.
Erik J. Amézquita +5 more
wiley +1 more source
Journal of Diabetes, Volume 15, Issue 9, Page 777-786, September 2023., 2023 Highlights Increased glutamate is associated with the development of diabetes. Glutamate increases plasminogen (PLG) levels through glutamate metabotropic receptor 5 activation with various insulin resistance‐related stresses. Glutamate inhibits the conversion of PLG to plasmin by increasing plasminogen activator inhibitor‐1.
Hyo Jung Lee +7 more
wiley +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2020 目的本研究旨在研究骨肉瘤细胞来源外泌体对靶器官微环境的调控作用及其分子机制。方法提取骨肉瘤细胞143B外泌体并鉴定，通过PKH26荧光染色后经尾静脉注入裸鼠体内，24 h后提取肝、脾、肺、肾及脑组织，荧光显微镜下计数不同视野红色荧光数量；通过免疫荧光检测不同类型细胞中外泌体摄取情况；143B外泌体与人肺成纤维细胞共培养，荧光显微镜检测摄取情况，进一步利用qPCR检测炎性因子IL-1β、IL-6及TNF-α表达水平，通过蛋白印迹法检测炎性信号通路NF-κB通路p-p65和MAPK通路p-ERK及p ...
谢显彪 +7 more
doaj
Rare Metals, Volume 45, Issue 3, March 2026.ABSTRACT Skin wound injuries are often accompanied by bacterial infections and severe inflammation. Especially, M1‐type macrophages at the wound site can trigger a cascade of inflammatory responses, mediating a vicious cycle of inflammation. Meanwhile, hypoxia further exacerbates vascular damage and constriction in the wound microenvironment, thereby ...
Xianfeng Wang +6 more
wiley +1 more source
Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT The limited osteogenic capacity of magnesium phosphate cement (MPC) has constrained its biomedical applications, underscoring the necessity to develop MPC with enhanced physical properties and bone‐forming capabilities. In this study, a multifunctional MPC system was developed by incorporating zoledronic acid‐loaded near‐infrared (NIR ...
Bin Wang +8 more
wiley +1 more source
American Journal of Botany, Volume 112, Issue 11, November 2025.Abstract Premise The proper classification of taxa is often debated, particularly when organisms lack qualitative diagnostic traits. Highbush cranberry taxa (Viburnum spp.) have been the subject of such disputes since their characterization by 18th‐ and 19th‐century botanists. Despite their allopatric distributions—V.
David G. Tork +3 more
wiley +1 more source
Evolution of petal patterning: blooming floral diversity at the microscale
New Phytologist, Volume 247, Issue 6, Page 2538-2556, September 2025.Summary The flowers of angiosperms are extraordinarily diverse. While most floral variation is visible to the naked eye, this diversity goes beyond the macroscale: Floral organs comprise an underappreciated range of cell types that generate a multitude of patterns across their surfaces and give rise to novel structures.
Erin Doody, Edwige Moyroud
wiley +1 more source
New Phytologist, Volume 247, Issue 1, Page 369-387, July 2025.Summary The butterfly‐shaped keel flower is a highly successful floral form in angiosperms. These flowers steer the mechanical interaction with bees and thus are hypothesized to accelerate pollinator‐driven diversification. The exceptionally labile evolution of keel flowers in Papilionoideae (Fabaceae) provides a suitable system to test this hypothesis.
Liming Cai +10 more
wiley +1 more source