Results 41 to 50 of about 8,352 (164)
Engineering of mesenchymal stem cell-derived exosomes and their application progress in the field of oral medicine [PDF]
In recent years, mesenchymal stem cell-derived exosomes (MSC-EXO) have garnered increasing attention in the field of stomatology and have become an established research area in biomedical research. This article reviews the engineering of exosomes derived
ZHAO Yunfeng, LIU Qian, LI Meng, LI Luying, ZHANG Wei, HU Xiantong, MA Chufan
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Research Advances in the Nutrient Composition and Functional Characteristics of Bovine Colostrum [PDF]
Bovine colostrum is the milk secreted by cows in the first few days after natural birth. It is rich in lactoferrin, immunoglobulin, antimicrobial peptides, growth factors and other active ingredients.
HAN Lihua, ZHU Shichen, Mike WEISER, MAO Xueying
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Summary Here, we investigated the molecular genetic basis of mite domatia, structures on the underside of leaves that house mutualistic mites, and intraspecific variation in domatia size in Vitis riparia (riverbank grape). Domatia and leaf traits were measured, and the transcriptomes of mite domatia from two genotypes of V.
Eleanore Jeanne Ritter +3 more
wiley +1 more source
环状RNA(circular RNA,circ RNA),作为非编码RNA(non-coding RNA)的重要成员,广泛存在于包括人类在内的多种原核及真核生物体内,对生命活动具有重要的调控作用,已成为非编码RNA研究领域的热点。与线性RNA相比,circ RNA呈共价闭合环状结构,具有结构稳定、序列保守、组织特异性、时空特异性等特点,在包括消化道肿瘤在内的多种疾病中发挥重要作用。circ RNA可通过竞争性吸附mi RNA、调控基因表达、参与蛋白质翻译等多种途径,参与肿瘤的发生发展,在肿瘤早期诊断 ...
施颖, 李金莹, 黄卫
core
Role of exosome-derived miRNA-21-5p/Smad7 in quartz dust-induced pulmonary fibrosis in rats [PDF]
BackgroundQuartz dust cannot be degraded in the lungs, and inhalation of a large amount of quartz dust in the occupational production process will lead to the occurrence of pulmonary fibrosis, and then develop into silicosis.
Jiarui HAO +6 more
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Developmental constraint underlies the replicated evolution of grass awns
Summary Replicated trait evolution can provide insights into the mechanisms underlying the evolution of biodiversity. One example of replicated evolution is the awn, an organ elaboration in grass inflorescences. Awns are likely homologous to leaf blades.
Erin Patterson +6 more
wiley +1 more source
目的本研究旨在比较成纤维细胞来源外泌体与间充质干细胞来源外泌体对小鼠急性皮肤创面的修复作用。方法体外分离培养原代人真皮成纤维细胞(hDF)并鉴定。用超速离心法提取人真皮成纤维细胞来源外泌体(hDF-EXO)、人骨髓间充质干细胞来源外泌体(hMSC-EXO)并鉴定;两种外泌体与hDF共培养24 h后,CCK8细胞增殖实验和划痕实验检测细胞增殖和迁移活性;采用8周龄雌性C57BL/6小鼠构建急性全层皮肤切除模型,在伤口上分别局部涂敷PBS(对照组)、hDF-EXO、hMSC-EXO进行治疗。术后第0、2、4、
李锐阳 +3 more
doaj
Preliminary study on the role and mechanism of ISG15 in exosomes in platinum resistance in ovarian cancer [PDF]
Background and purpose: Epithelial ovarian cancer (EOC) has a poor prognosis and is prone to developing resistance to platinum-based chemotherapy. Exosomes are currently believed to be involved in platinum resistance in ovarian cancer.
TIAN Yanan, ZHENG Hui, YAN Tianqing, ZHANG Heng, LU Renquan, GUO Lin
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Abstract Premise There are advantages to flowering early in the spring, including greater pollinator fidelity and longer fruit maturation time. But plant phenology has advanced in recent years, making many plants vulnerable to freezing damage from late frosts.
Danielle A. Lake Diver +1 more
wiley +1 more source
外泌体环状RNA诱导HK-2细胞凋亡在感染性休克AKI中的研究
目的 探究外泌体环状RNA诱导HK-2细胞凋亡在感染性休克相关性急性肾损伤的作用机制。方法 分为感染性休克相关性急性肾损伤患者组和健康人对照组,采集血标本。检测外泌体标记蛋白,鉴定出两组外泌体,对外泌体环状RNA进行实时PCR分析。对两组的HK-2细胞进行凋亡检测。结果 10例感染性休克AKI入院患者,10例健康人对照。鉴定表面外泌体标记蛋白包括HSP70和TSG101。两组均鉴定出外泌体。与对照组相比,感染性休克AKI组circ-Ttc3 ...
李秀君, 李岩, 张春媚, 杨海玲
doaj +2 more sources

