Results 21 to 30 of about 710 (150)
Analysis of characteristics of infectious pathogens in malignant tumors combined with bloodstream infection and significance of serum glucose detection [PDF]
, 2023 Background and purpose: The incidence rate of bloodstream infection (BSI) in patients with malignant tumor increases gradually with the progress of anti-tumor treatment. The treatment outcome is closely related to the infection of pathogen.
CHEN Zhujun, DING Zhimin, MA Xiaolu, WANG Yanchun, HU Haoyun, LU Renquan, GUO Lin
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, 2019 活性氧簇(ROS)是生物在有氧环境中进行能量代谢时产生的一类分子的总称,ROS不仅在动物、植物以及细菌的生理过程中发挥着重要的作用,也在研究抗生素杀菌和细菌耐药性的产生上有着重要的功能,添加ROS清除剂有助于我们更好的研究ROS在细菌对抗菌剂耐受中的作用。本文主要通过对常见的ROS清除剂过氧化氢酶、硫脲、联吡啶、DMSO、褪黑素和其他较为常见的清除剂等化合物在抗生素杀菌过程中的作用机制、ROS清除剂添加对细菌耐受性的影响及其他生理作用进行综述 ...
刘小东 +4 more
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Non-clostridial Gas-forming Infection in Diabetes：Clinical Analysis of Two Cases [PDF]
, 2022 Non-clostridial organism can produce pneumoderma by breaking down sugar and other substrates in necrotic tissues, and non-clostridial gas-forming infection is usually seen in diabetic patients with poor glycemic control.
WU Yuan, LYU Hongjun, YAO Xiaoli, LIU Juan
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Advances in bacterial iron homeostasis and antibiotics killing mechanism [PDF]
, 2016 传统研究认为不同种类的抗生素有其各自不同的杀菌途径,然而近年人们发现了一条抗生素杀菌的共用通路,那就是当细菌细胞受到抗生素致死性刺激时,呼吸链代谢异常产生大量活性氧簇(ROS),而铁离子对ROS介导的杀菌至关重要。本文参阅近年来国内外研究结果,介绍了铁吸收、储存和利用有关的细菌铁代谢系统及其调控机制,重点讨论铁离子的调控及其与抗生素介导的ROS形成的相互作用关系。对于细菌耐药机制的研究与寻找新型药物作用靶点,探索有效控制手段和开发新药有重要意义。Previous research suggested ...
冯锦芝 +4 more
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Analysis of foodborne diseases pathogen infection characteristics in Haining City, Zhejiang Province from 2014 to 2023 [PDF]
ObjectiveTo analyze the epidemiological characteristics of pathogens in foodborne disease cases in Haining City, Zhejiang Province, and to provide a basis for the prevention and investigation of foodborne diseases and outbreak events.MethodsInformation ...
LI Minchao +4 more
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Analysis of monitoring results of food microbial pathogenic factors in Zhoushan City from 2017 to 2019 [PDF]
, 2020 Objective To understand the contamination status of microorganisms and pathogenic factors in 19 kinds of food in Zhoushan City, so as to provide basic data for food safety risk monitoring and early warning.
Fangyi ZHU +5 more
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Zhongguo shiyan zhenduanxue, 2009 目的了解本院2008年住院患者产超广谱β-内酰胺酶大肠埃希菌的感染情况为临床防控及治疗产超广谱β-内酰胺酶大肠埃希菌引起的感染提供科学依据。方法对2008年1-12月间本院感染大肠埃希菌的住院患者进行调查,并进行药敏检测,结果依据2009年CLSI标准,采用WHONET 5.4软件进行统计分析。结果本院在2008年1-12月间的住院患者中,检出大肠埃希菌306例,ESBLs阳性率41.6%;产ESBLs大肠埃希菌检出较多的科室为泌尿外科（24例,占17.0%）,检出标本最多的为尿标本（63例,占44.7%
褚云卓 +3 more
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Zhongguo shiyan zhenduanxue, 2023 目的 探讨新生儿早期肠道菌群的定植情况及影响因素。方法 选取2021年9月～2022年9月青海省妇女儿童医院新生儿298例作为研究对象，在所有新生儿出生后第5～7 d采集新鲜粪便样本，采取全自动微生物分析仪对可疑菌落实施菌种鉴定，分离菌株(肺炎克雷伯菌、肠球菌及大肠埃希菌),计算细菌定植率。统计分析粪便培养结果，并比较不同胎龄、不同分娩方式、不同抗生素应用情况的新生儿细菌定植情况。结果 (1)本组298例新生儿中，共检出肺炎克雷伯菌36株、肠球菌126株、大肠埃希菌171株；(2 ...
王正岭
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Analysis of Gut Flora in a Mouse Model of Esophageal Squamous Cell Carcinoma in Situ [PDF]
, 2022 BackgroundWith the application and development of high-throughput sequencing-based approaches for gut flora analysis, increasing studies have confirmed that gut flora is closely related to the development of various cancers.
ZHANG Yushuang, YU Fuyang, WU Zhongbing, WANG Yiran, LI Jing
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Association of TolC expression with resistance to tetracycline in Escherichia coli K-12 [PDF]
, 2007 随着抗生素的开发与使用,细菌在对多种抗生素的适应过程中逐渐发展出对抗生素耐药的反应机制。TolC是药物排出转运体系的外膜成分,与AcrAB一起形成主要的药物排出泵,有关其表达量与耐药间的关系目前尚不清楚。试验将tolC克隆到pET-32a载体上进行诱导表达,镍柱纯化,免疫新西兰大白兔,获得1:4000的抗血清。Western blotting分析表明,TolC的表达量在耐四环素的大肠埃希菌K-12中比对照组提高50%。细菌TolC高表达试验发现,其MIC从100μg/ml提高到200μg/ml ...
张丹凤, 王三英, 黄传钟
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