Results 11 to 20 of about 3,887 (154)
Synthetic microbial consortia with programmable ecological interactions
Abstract Central to the composition, structure and function of any microbial community is the complex species interaction web. But understanding the overwhelming complexity of ecological interaction webs has been challenging, owing at least partly to the lack of efficient tools for disentangling species interactions in natural or artificial microbial ...
Shuyao Li +8 more
wiley +1 more source
Background Bacterial densities likely fluctuate during infection and may exceed the bacterial density used in susceptibility testing. As such, investigation of bacterial killing by antibiotics over a range of varying bacterial densities may provide important differences between compounds and could impact drug selection for therapy.
Joseph M. Blondeau, Shantelle D. Fitch
wiley +1 more source
ABSTRACT This study introduces novel nonequiatomic TiZrCoCrMoCux (x = 0, 5, 10; at%) medium‐entropy alloys (MEAx) tailored for orthopedic implants, synergistically combining the biocompatibility of Ti‐based alloys, the wear resistance of CoCrMo alloys, and the antibacterial/osteogenic attributes of Cu. The alloy's microstructure, mechanical properties,
Hang Yu +9 more
wiley +1 more source
Background – Biofilm production by canine otitis externa (COE) pathogens and resistance development to multiple antimicrobials are commonly reported problems in veterinary practice. The use of adjuvants to disrupt biofilms may be a viable adjunctive therapy.
Bhumika F. Savaliya +3 more
wiley +1 more source
S221T/D225Y mutations of Escherichia coli RecA can transfer RecA from cytoplasm to nucleus in HeLa cells [PDF]
RecA/Rad51家族蛋白在进化上是非常古老而又保守的蛋白家族。大肠杆菌RecA基因在同源重组、DNA修复、SOS途径、突变和细胞分裂中起重要作用。人Rad51基因是大肠杆菌RecA基因的直向同源基因,两者起源于同一个祖先基因。人Rad51基因主要参与DNA的修复和重组,并且与肿瘤发生关系密切。原核细胞与真核细胞最大的区别在于原核细胞没有以核模为界限的细胞核,而蛋白质的入核转运机制是一个十分复杂的生物学过程,需要核孔复合体(NPC)、核定位信号(NLS)、核转运受体、RanGTP蛋白等共同参与 ...
孙旭利
core
Clone、construction and expression of Synechocystis sp.PCC 6803 Acetyl- CoA carboxylase gene for fat production [PDF]
在化石燃料日益枯竭、环境污染逐渐威胁人类生存的今天,生物柴油在提供可再生能源的同时还可以减少温室气体,从而受到世界各国的广泛重视。蓝藻为光合自养微生物,是大气碳循环主要贡献者,其生物柴油产量是油料作物的8~24倍。乙酰辅酶A羧化酶(acetyl-coenzymeAcarboxylase,ACCase)是生物体内脂肪生物合成的关键酶,研究发现,过量表达ACCase能够促进生物体脂肪的合成。相对于蓝藻,大肠杆菌具有遗传背景清楚、生长速度快等特点 ...
周赞虎
core
Background – Norway spruce (Picea abies) resin‐based products are used in human medicine. A resin‐based otic rinse also could be useful in supportive care of canine otitis externa (COE), yet information on its antimicrobial effect against canine pathogens or ototoxicity is lacking.
Elina Aimo‐Koivisto +5 more
wiley +1 more source
Study on disinfection and sterilization of high algae-laden water with Hydroxyl radicals [PDF]
消毒灭菌是饮用水处理工艺中的重要组成部分。而地表水富营养化现象日益加剧,导致水源地高藻频发,增加了饮用水常规氯消毒处理工艺的负担,严重威胁城市供水卫生安全。如何平衡饮用水微生物安全性与化学安全性,成为当前高藻饮用水消毒技术研究的重要内容。本文依托国家科技支撑计划项目“高藻水源地供水卫生保障羟基自由基氧化技术研发与示范”(NO.2013BAC06B00),针对厦门市重要水源地九龙江北溪流域水体,通过大气压强电离放电规模制备羟基自由基(•OH),建立了高藻饮用水•OH消毒灭菌处理工艺,
黄孟斌
core
Fabrication and bacterial adhesion of metal dry electrode with surface microstructure arrays [PDF]
为开发出高性能生物医用干式电极,提出了利用激光微铣-重铸加工方法,实现了表面具有微结构阵列特征的新型金属干式电极的制造成形。在分析电极表面微观形; 貌的基础上,研究了电极表面的润湿性能,并重点研究了扫描间距、扫描速度和扫描次数等加工参数对大肠杆菌粘附性能的影响规律。研究结果表明:在一定工艺参; 数条件下所加工出具有微结构阵列特征的电极的接触角可达150°以上,表现出超疏水的特性。在不同扫描间隙和扫描次数条件下加工出的电极对大肠杆菌的粘附; 性能具有较大影响,在选择0.1; mm扫描间隙时 ...
刘韶宇 +6 more
core +1 more source
The optimized expression technology of marine animal-sourced antimicrobial peptides in Pichia pastoris and the development of antimicrobial peptide as feedstuff additive [PDF]
抗生素污染问题是目前影响我国水产养殖业可持续健康发展的重大科技问题,抗生素(antibiotics)作为常用抗菌药物,被广泛应用于水产养殖业,但是抗生素超标所引起的细菌耐药性问题已成为全球公共健康问题,因此寻找抗生素的有效替代品是目前国内外本领域的研究热点之一。抗菌肽(antimicrobialpeptide)是先天性免疫的重要组分,广泛存在于生物界的各个门类,进化上相对保守,具有广谱抗菌活性、且不会产生细菌耐药性,被预言为最有希望替代抗生素的天然药物,具有广阔的应用前景 ...
彭会
core

