Results 1 to 10 of about 5,101,806 (142)

Successful surgical removal of a pheochromocytoma in a mare via trans‐costal approach

open access: yesEquine Veterinary Journal, Volume 55, Issue 6, Page 1012-1020, November 2023., 2023
Abstract Background Pheochromocytomas have been previously reported in horses, but successful antemortem diagnosis and surgical removal without recurrence of clinical signs have not been described. Objective To report the clinical presentation, diagnostic evaluation, surgical technique, anaesthetic management and post‐operative care of a mare diagnosed
Thomas J. O'Brien   +6 more
wiley   +1 more source

COX-2和CEA在大肠癌中的表达及其与临床病理学特征的关联

open access: yesZhongguo shiyan zhenduanxue, 2022
目的 研究COX-2和CEA在大肠癌中的表达及其与临床病理特征之间的关联。方法 随机选取大连市中心医院病理科于2017年7月至2019年7月间经手术切除的大肠癌石蜡切块50例,选取经消化内镜活检的大肠腺瘤组织50例,选取大肠癌远端部位距肿瘤边缘15cm以外正常大肠黏膜组织50例,采用免疫组织化学检测上述组织中COX-2和CEA的表达。结果 (1)大肠癌和大肠腺瘤中COX2和CEA的表达均明显高于正常大肠黏膜组织,大肠腺瘤中COX2和CEA的表达均明显高于正常大肠黏膜组织,差异有统计学意义 ...
张辉, 王朝晖
doaj  

Dual Checkpoint Inhibition with Ipilimumab plus Nivolumab After Progression on Sequential PD‐1/PDL‐1 Inhibitors Pembrolizumab and Atezolizumab in a Patient with Lynch Syndrome, Metastatic Colon, and Localized Urothelial Cancer

open access: yesThe Oncologist, Volume 24, Issue 11, Page 1416-1419, November 2019., 2019
Abstract Immune checkpoint blockade (ICB) is an approved therapy for advanced metastatic mismatch repair (MMR)‐deficient cancer regardless of tissue of origin. Although therapy is effective initially, recurrence rates are significant, and long‐term outcomes remain poor for most patients.
Arthur Winer   +7 more
wiley   +1 more source

多梳基因家族成员的Bmi-1与Ki67蛋白表在大肠肿瘤组织的表达情况及预后相关性

open access: yesZhongguo shiyan zhenduanxue, 2021
目的探讨多梳基因家族成员的Bmi-1与Ki67蛋白表在大肠肿瘤组织的表达情况及预后相关性。方法选取天津市宁河区医院2017年2月到2019年2月共收治的100例大肠肿瘤患者作为研究对象,所有患者通过病理检查发现,100例大肠肿瘤患者中有60例为大肠癌,分,40例为大肠腺瘤患者,另取同期20例健康体检患者的正常大肠黏膜组织,分为对照组,分析大肠癌、大肠腺瘤和正常大肠黏膜组织Bmi-1和Ki67的表达与临床病理特征及患者生存的关系。结果Bmi-1和Ki67在大肠癌、腺瘤和正常大肠黏膜组织中的表达率分别为25.
郭俊龙, 梁滨, 田伟军
doaj  

Comparison of ultrasound with computed tomography and whole‐body diffusion‐weighted MRI in prediction of surgical outcome using ESMO‐ESGO criteria in patients with tubo‐ovarian carcinoma: prospective ISAAC study

open access: yesUltrasound in Obstetrics &Gynecology, Volume 67, Issue 2, Page 207-219, February 2026.
ABSTRACT Objective To test the non‐inferiority of extended abdominopelvic ultrasound examination compared with contrast‐enhanced computed tomography (CT) and whole‐body diffusion‐weighted magnetic resonance imaging (WB‐DWI/MRI) in discriminating preoperatively between resectable and non‐resectable disease based on the European Society for Medical ...
D. Fischerova   +26 more
wiley   +1 more source

胃肠间质瘤的彩色多普勒超声表现与病理对照分析

open access: yesZhongguo shiyan zhenduanxue, 2014
胃肠道间质瘤(GIST)是一种较为少见的来源于胃肠道间叶组织的肿瘤。虽然胃肠道间叶源性肿瘤在胃肠道肿瘤中所占比例不大,但是它的种类繁多,并且形态各异。这种肿瘤既不归属于神经源性肿瘤类型,也不归属于平滑肌瘤类型。目前,国内外大部分报道证实,来源于胃肠道的绝大多数梭形细胞性肿瘤是一种非定向分化的间质瘤,它不具有平滑肌或神经分化特征[1]。本文通过选取在我院经过手术并术后病理证实的21例胃肠间质瘤患者 ...
齐娜, 佟凌霞, 张箭
doaj  

大肠侧向发育型肿瘤Bcl-2和Caspase9蛋白的表达研究

open access: yesZhongguo shiyan zhenduanxue, 2010
目的探讨大肠侧向发育型肿瘤Bcl-2和Caspase9的基因表达改变,及其与大肠腺癌的关系。方法应用免疫组化SP法测定大肠腺癌、大肠腺瘤、大肠侧向发育型肿瘤的Bcl-2和Caspase9的表达。结果正常粘膜中Bcl-2表面上皮表达阴性,在腺癌组明显低于腺瘤组和LST良性组 ...
张斌   +7 more
doaj  

不同时期结直肠癌细胞中CD44v6表达变化的研究

open access: yesZhongguo shiyan zhenduanxue, 2009
目的在本研究中检测63例结直肠癌组织中CD44v6的表达情况,以评估CD44v6在结直肠肿瘤发生发展过程中的作用。方法采用HE染色,光镜,和免疫组化方法,观察不同病程阶段、不同病变范围的结直肠癌对细胞粘附分子CD44v6不同的表达情况。结果63例肿瘤组织标本中,对CD44v6表达有24例强阳性,13例阳性(中度染色),26例阴性。CD44v6的阴性或阳性表达(中度染色)与肿瘤大小 ...
李滨   +4 more
doaj  

胃间质瘤CT诊断探讨

open access: yesZhongguo shiyan zhenduanxue, 2013
胃肠道间质瘤是胃肠道肌壁间叶源性肿瘤,发病率较低,可发生于胃肠道及胃肠道外,如大网膜及肠系膜等,约60%-70%发生于胃,胃间质瘤占胃肿瘤的1%-3%。胃肠道间质瘤内含梭形细胞,过去多诊断为平滑肌类肿瘤,随着病理学不断发展,电镜和免疫组化发现,肿瘤是由梭形细胞和上皮样细胞组成,而不含平滑肌细胞 ...
尹继磊, 杨素君, 刘峥, 霍強
doaj  

Survivin和Caspas3在侧向发育型大肠肿瘤中的表达

open access: yesZhongguo shiyan zhenduanxue, 2011
目的研究凋亡相关基因Survivin和Caspase3蛋白在侧向发育型大肠肿瘤(LST)中的表达。方法应用免疫组织化学方法检测良性LST、大肠腺瘤、大肠腺癌及其正常黏膜组织中Survivin和Caspase3的蛋白表达。结果 Sur-vivin在大肠腺癌(61.9%)高表达,良性LST(21.7%)和大肠腺瘤(20.6%)表达降低,而在正常黏膜组织不表达。Cas-pase3在正常黏膜高表达(90.9%),在良性LST(60.9%)和大肠腺瘤(64.7%)表达降低,在大肠腺癌(42.9%)低表达 ...
吴晓冬   +5 more
doaj  

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