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18F-FDGPET/CT显像检测SD大鼠肝纤维化 [PDF]
【目的】探讨18F-FDGPET/CT显像评价SD大鼠肝纤维化疾病。【方法】12只(170±10)g雄性SD大鼠随机分为模型组(TAA组)和对照组,每组6只。模型组大鼠每周两次腹腔注射4%硫代乙酰胺,每次剂量200mg/kg;对照组腹腔注射等比例生理盐水。注射6周后对两组大鼠行18F-FDGPET/CT显像,检测肝组织摄取18F-FDG情况。显像后解剖两组大鼠观察肝脏解剖形态学变化并取其肝脏用于HE染色、Masson染色和羟脯氨酸含量测定。【结果】模型组解剖形态显示肝脏肿胀、表面欠光滑、边缘圆钝 ...
苏舒 +7 more
doaj +1 more source
对赤大袋鼠进行行为训练有利于建立赤大袋鼠与饲养员的互信关系,减少赤大袋鼠在饲养管理工作中的应激反应。选取4只成年雌性赤大袋鼠进行了为期1个月的行为训练工作。训练目标为:赤大袋鼠能够跟随目标棒移动,并主动上秤进行体重称量。在行为训练过程中经历了脱敏、建立响片条件反射、引入目标棒、跟随目标棒移动、奖励延迟、行为保持等几个阶段。克服了赤大袋鼠白天活跃度低,可视能力弱的训练难点,大大减少了健康体检时赤大袋鼠体重的称量时间。
赵玲玲 王国栋 梁作敏 付兆水 胡 俊 蒋 迟
doaj +1 more source
目的 探讨高原环境对移居大鼠子代体重及大脑的影响。方法 将16只(12只雌鼠,4只雄鼠)8周龄wistar大鼠按3∶1雌雄比随机分为高海拔组和低海拔组,待大鼠合笼受孕自然分娩后,比较两组子鼠出生后1周内体重、脑重及脑指数,并取子鼠大脑组织做病理切片染色观察。结果 高海拔组子鼠出生后1周内体重均低于低海拔组 ...
龚嘎蓝孜 +4 more
doaj
中小企业融资难这个问题,就比如像一只老鼠,怎么样把这只老鼠捉到?我们现在的政策是什么?是把大象赶出来去捉老鼠,捉得到吗?即使抓到了’这么点肉,够塞牙缝吗?为了捉老鼠 ...
Xu, Xiaonian
core +6 more sources
Tracing change in the public perception of plants: insights from archives and social media in China
As urbanization accelerates, historic gardens serve as vital cultural treasures that offer spiritual and cultural support to the public. This study proposes an innovative approach that merges historical records from the Qing Dynasty with contemporary social media data to explore changes in public perceptions of these gardens.
Dong Xu +4 more
wiley +1 more source
目的探讨抗糖药物卡格列净(CGLZ)对阿霉素所致肾病综合征(NS)模型大鼠的治疗作用,以及超声造影(CEUS)联合彩色多普勒血流显像(CDFI)在治疗过程中的评价作用。方法56 只SD 雄性大鼠随机分为正常组(NG)、模型组(MG)、泼尼松(PAT)组(PG)、小剂量CGLZ 组(LSCG)、大剂量CGLZ 组(HSCG)、小剂量CGLZ + PAT 组(LUCG)和大剂量CGLZ +PAT 组(HUCG),每组8 只。采用阿霉素2 次尾静脉注射法诱导制备NS 大鼠模型,以常规PAT ...
洪文娟 +6 more
doaj
ABSTRACT Cisplatin‐related acute kidney injury (CP‐AKI) is a serious complication of cisplatin (CP) treated patients with cancer with high morbidity and mortality rates. It is directly related to the abnormal accumulation of CP in renal tubular epithelial cells, causing metabolic toxicity, DNA damage, and oxidative stress.
Minghe Jiang +12 more
wiley +1 more source
ABSTRACT Ti‐15Mo‐2.5Ag alloy exhibited a low modulus and strong antibacterial ability but poor bioactivity. To resolve this problem, sandblasting and anodization were used to create a hydrophilic and nano‐Ag2O‐containing TiO2 coating. Subsequently, the microstructure and physicochemical properties were investigated by scanning electron microscopy, X ...
Yanchun Xie +11 more
wiley +1 more source
ABSTRACT The regeneration of osteoporotic bone defects is severely hampered by compromised endogenous healing capacity, demanding advanced strategies that actively orchestrate pro‐osteogenic microenvironments. Here, we report an integrated, self‐powered osteo‐regenerative system that uniquely leverages a dual ultrasound‐responsive piezoelectric ...
Bing Tan +6 more
wiley +1 more source
ABSTRACT Infected bone defects represent a dual therapeutic challenge demanding concurrent infection inhibition and osteogenesis promotion. Systemic antibiotic administration is taken as a classical treatment protocol but often yields inadequate local antibiotic concentrations and delayed bone repair.
Xucai Wang +8 more
wiley +1 more source

