Results 11 to 20 of about 9,065 (123)
Zhongguo shiyan zhenduanxue, 2010 目的通过对电针治疗后大鼠局灶性脑缺血模型（MCAO）酪氨酸羟化酶（tyrosine hydroxylase,TH）表达改变的观察,探讨电针对脑可塑性的影响。方法将大鼠随机分为对照组（正常大鼠）、实验组（局灶性脑缺血的大鼠）、治疗组（局灶性脑缺血的大鼠+针刺）,采用荧光定量RT-PCR技术观察各组大鼠TH的动态变化。结果治疗组大鼠TH活性比实验组有显著提高呈阳性表达 ...
田明秀, 陈加俊, 赵静, 黄艳苹
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Rare Metals, Volume 45, Issue 5, May 2026.ABSTRACT The efficacy of immunotherapy in triple‐negative breast cancer (TNBC) is often limited, whereas the immunotherapeutic potential of pyroptosis is frequently undermined by a compensatory surge in mitophagy. To address this challenge, this study developed a reactive oxygen species (ROS)‐responsive and mitochondria‐targeted nanomicelle (POM@CTT ...
Qingqing Dou +6 more
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Zhongshan Daxue xuebao. Yixue kexue ban, 2006 【目的】探讨自发高血压大鼠心肌肥厚与心室颤动阈值的关系。【方法】20只雄性自发高血压大鼠，随机分成10周龄组（n=10）和18周龄组（n=10）；10只10周龄雄性Wistar大鼠为对照组。分别测定3组大鼠的动脉收缩压、心脏质量指数、心室有效不应期和心室颤动阈值。【结果】①自发高血压大鼠的动脉收缩压和心脏质量指数明显高于Wistar大鼠（P〈0．001），心室颤动阈值明显低于Wistar大鼠（P〈0．001）；②自发高血压大鼠中 ...
黄至斌 +4 more
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Studying the Zhuangzi: An Institutional Approach
Philosophy Compass, Volume 21, Issue 3, May/June 2026.ABSTRACT Comparative political philosophy has recently grown in prominence, but most attention focuses on Confucians such as Confucius, Mencius, and Xunzi. Daoists, particularly Zhuangzi, have long been neglected. This paper proposes an “institutional approach” to Zhuangzi's philosophy, examining what institutions can create a social environment that ...
Baldwin Wong
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2010 目的观察单宁酸（tannic acid,TA）对链脲佐菌素（STZ）诱发糖尿病（DM）大鼠血清及肾脏C反应蛋白（CRP）表达的影响。方法 70只雄性Wistar大鼠随机分为正常对照组、模型组、氨基胍（AG）组和TA低高剂量组,给药10周后处死大鼠。ELISA法检测各组大鼠血清CRP水平,免疫组织化学染色观察CRP在肾组织中的表达。结果 DM大鼠血清及肾组织CRP表达增加,单宁酸可降低DM大鼠血清CRP水平,下调肾组织CRP蛋白的表达。结论单宁酸可改善糖尿病大鼠微炎症状态 ...
王兴国 +3 more
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Rare Metals, Volume 45, Issue 4, April 2026.ABSTRACT Diabetic wound infections are a common complication of diabetes, which severely impact patients' quality of life. Effective treatment of diabetic wound infections remains one major challenge in the clinic, partially due to the formation of bacterial biofilm and antibiotic resistance.
Liang Zhou +8 more
wiley +1 more source
Tocilizumab对肺动脉高压大鼠IL-6及survivin的影响
Zhongguo shiyan zhenduanxue, 2013 目的观察tocilizumab对肺动脉高压大鼠白细胞介素-6（IL-6）和survivin的表达水平的影响。方法通过腹腔注射野百合碱诱导建立肺动脉高压大鼠模型,观察tocilizumab对肺动脉高压大鼠IL-6和survivin的表达水平的影响。结果 Tocilizumab干预组大鼠和空白对照组大鼠mPAP、IL-6和survivin含量明显低于实验对照组 ...
姚健 +4 more
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Rare Metals, Volume 45, Issue 4, April 2026.ABSTRACT Constructing a porous scaffold with the essential features of natural cancellous bone, including structural architecture and biochemical cues, is one of the pivotal factors for effective bone regeneration. In this study, a biomimetic composite porous Gelatin fibrous scaffold (SrHA/Gelatin) incorporating ultralong strontium‐doped hydroxyapatite
Yin‐Chuan Wang +8 more
wiley +1 more source
野生动物学报, 2015 对赤大袋鼠进行行为训练有利于建立赤大袋鼠与饲养员的互信关系,减少赤大袋鼠在饲养管理工作中的应激反应。选取4只成年雌性赤大袋鼠进行了为期1个月的行为训练工作。训练目标为:赤大袋鼠能够跟随目标棒移动,并主动上秤进行体重称量。在行为训练过程中经历了脱敏、建立响片条件反射、引入目标棒、跟随目标棒移动、奖励延迟、行为保持等几个阶段。克服了赤大袋鼠白天活跃度低,可视能力弱的训练难点,大大减少了健康体检时赤大袋鼠体重的称量时间。
赵玲玲 王国栋 梁作敏 付兆水 胡 俊 蒋 迟
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Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT Intervertebral disc degeneration (IDD) is a predominant cause of low back pain, significantly impacting quality of life. Mitochondrial fitness is essential in the progression of IDD, as it regulates cellular senescence and pyroptosis. This study investigates the role of mitochondrial caseinolytic protease P (ClpP) in alleviating senescence and
Kun Wang +7 more
wiley +1 more source