Results 1 to 10 of about 5,025,780 (160)
Uncovering correlates of decline and critical refuges for a threatened terrestrial mammal
Conservation Biology, Volume 40, Issue 4, August 2026.Abstract Globally, the geographic ranges of numerous species are contracting. Identifying spatiotemporal patterns of threat impact can illuminate why species decline in some parts of their range but persist in others. We developed a correlative approach to identify species’ response thresholds and locate ecological refuge areas associated with ...
Natalya M. Maitz +5 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2010 目的通过对电针治疗后大鼠局灶性脑缺血模型（MCAO）酪氨酸羟化酶（tyrosine hydroxylase,TH）表达改变的观察,探讨电针对脑可塑性的影响。方法将大鼠随机分为对照组（正常大鼠）、实验组（局灶性脑缺血的大鼠）、治疗组（局灶性脑缺血的大鼠+针刺）,采用荧光定量RT-PCR技术观察各组大鼠TH的动态变化。结果治疗组大鼠TH活性比实验组有显著提高呈阳性表达 ...
田明秀, 陈加俊, 赵静, 黄艳苹
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Rare Metals, Volume 45, Issue 7, July 2026.ABSTRACT The pathogenesis of diabetic foot ulcers is complex, often involving polymicrobial infection and persistent inflammatory responses, which lead to delayed or nonhealing wounds, posing a formidable clinical challenge. Existing photodynamic therapy reagents and traditional treatments generally address only a single pathological aspect, and the ...
Yu Zhang +16 more
wiley +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2006 【目的】探讨自发高血压大鼠心肌肥厚与心室颤动阈值的关系。【方法】20只雄性自发高血压大鼠，随机分成10周龄组（n=10）和18周龄组（n=10）；10只10周龄雄性Wistar大鼠为对照组。分别测定3组大鼠的动脉收缩压、心脏质量指数、心室有效不应期和心室颤动阈值。【结果】①自发高血压大鼠的动脉收缩压和心脏质量指数明显高于Wistar大鼠（P〈0．001），心室颤动阈值明显低于Wistar大鼠（P〈0．001）；②自发高血压大鼠中 ...
黄至斌 +4 more
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Rare Metals, Volume 45, Issue 5, May 2026.ABSTRACT Managing diabetic wounds requires simultaneously addressing their infectious, oxidative, and regenerative impairments. To address this, this study integrates a piezoelectric BiOCl@CuSe heterojunction (PFM‐verified) into an injectable F127/HA hydrogel, creating an ultrasound‐responsive smart dressing.
Jiayan Guo +5 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2010 目的观察单宁酸（tannic acid,TA）对链脲佐菌素（STZ）诱发糖尿病（DM）大鼠血清及肾脏C反应蛋白（CRP）表达的影响。方法 70只雄性Wistar大鼠随机分为正常对照组、模型组、氨基胍（AG）组和TA低高剂量组,给药10周后处死大鼠。ELISA法检测各组大鼠血清CRP水平,免疫组织化学染色观察CRP在肾组织中的表达。结果 DM大鼠血清及肾组织CRP表达增加,单宁酸可降低DM大鼠血清CRP水平,下调肾组织CRP蛋白的表达。结论单宁酸可改善糖尿病大鼠微炎症状态 ...
王兴国 +3 more
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Rare Metals, Volume 45, Issue 5, May 2026.ABSTRACT The efficacy of immunotherapy in triple‐negative breast cancer (TNBC) is often limited, whereas the immunotherapeutic potential of pyroptosis is frequently undermined by a compensatory surge in mitophagy. To address this challenge, this study developed a reactive oxygen species (ROS)‐responsive and mitochondria‐targeted nanomicelle (POM@CTT ...
Qingqing Dou +6 more
wiley +1 more source
Tocilizumab对肺动脉高压大鼠IL-6及survivin的影响
Zhongguo shiyan zhenduanxue, 2013 目的观察tocilizumab对肺动脉高压大鼠白细胞介素-6（IL-6）和survivin的表达水平的影响。方法通过腹腔注射野百合碱诱导建立肺动脉高压大鼠模型,观察tocilizumab对肺动脉高压大鼠IL-6和survivin的表达水平的影响。结果 Tocilizumab干预组大鼠和空白对照组大鼠mPAP、IL-6和survivin含量明显低于实验对照组 ...
姚健 +4 more
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Studying the Zhuangzi: An Institutional Approach
Philosophy Compass, Volume 21, Issue 3, May/June 2026.ABSTRACT Comparative political philosophy has recently grown in prominence, but most attention focuses on Confucians such as Confucius, Mencius, and Xunzi. Daoists, particularly Zhuangzi, have long been neglected. This paper proposes an “institutional approach” to Zhuangzi's philosophy, examining what institutions can create a social environment that ...
Baldwin Wong
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2013 目的肝纤维化动物模型大鼠应用雷帕霉素后,检测大鼠肝组织切片中转移生长因子（TGF-β1）表达,探讨雷帕霉素与肝纤维化病理演变的相关性。方法作者将实验大鼠随机分为3组:①正常对照组大鼠（A组）;②肝纤维模型组大鼠（B组）;③肝纤维模型灌注雷帕霉素组（C组）。C组大鼠按2mg/kg体重胃内灌注雷帕霉素,每天1次,持续2周。3组大鼠同期处死,取肝组织进行形态学及组织学研究分析。结果 3组大鼠肝组织切片经HE及免疫组织化等染色后,图片经Image-pro plus 6.0图像分析软件整理。A、B、C ...
钟志宏, 戴东, 陈土明, 吴祖超
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