Results 1 to 10 of about 9,065 (123)

高原环境对移居大鼠子代体重及大脑的影响

open access: yesZhongguo shiyan zhenduanxue, 2021
目的 探讨高原环境对移居大鼠子代体重及大脑的影响。方法 将16只(12只雌鼠,4只雄鼠)8周龄wistar大鼠按3∶1雌雄比随机分为高海拔组和低海拔组,待大鼠合笼受孕自然分娩后,比较两组子鼠出生后1周内体重、脑重及脑指数,并取子鼠大脑组织做病理切片染色观察。结果 高海拔组子鼠出生后1周内体重均低于低海拔组 ...
龚嘎蓝孜   +4 more
doaj  

Ultrasound‐Driven Dual Piezocatalytic–Electrical Scaffold Synergistically Promotes Osteoporotic Bone Healing

open access: yesRare Metals, Volume 45, Issue 8, August 2026.
ABSTRACT The regeneration of osteoporotic bone defects is severely hampered by compromised endogenous healing capacity, demanding advanced strategies that actively orchestrate pro‐osteogenic microenvironments. Here, we report an integrated, self‐powered osteo‐regenerative system that uniquely leverages a dual ultrasound‐responsive piezoelectric ...
Bing Tan   +6 more
wiley   +1 more source

Dual‐Bioactive Lignin‐Based Microcarrier Hydrogel Platform via Metal Salt Crosslinking for Synchronized Infection Eradication and Bone Regeneration

open access: yesRare Metals, Volume 45, Issue 8, August 2026.
ABSTRACT Infected bone defects represent a dual therapeutic challenge demanding concurrent infection inhibition and osteogenesis promotion. Systemic antibiotic administration is taken as a classical treatment protocol but often yields inadequate local antibiotic concentrations and delayed bone repair.
Xucai Wang   +8 more
wiley   +1 more source

Informal supply chains of wild meat from rural Amazonia and food security in an urban center

open access: yesConservation Biology, Volume 40, Issue 4, August 2026.
Abstract Iquitos, the most populated city in the Peruvian Amazon, is a hub in the regional supply chain of wild meat and supplies urban consumers. Studies on wild meat consumption have focused primarily on markets, limiting the scope of species considered to those that are economically valuable and potential inferences from those data.
Fiorella Briceño Huerta   +3 more
wiley   +1 more source

Uncovering correlates of decline and critical refuges for a threatened terrestrial mammal

open access: yesConservation Biology, Volume 40, Issue 4, August 2026.
Abstract Globally, the geographic ranges of numerous species are contracting. Identifying spatiotemporal patterns of threat impact can illuminate why species decline in some parts of their range but persist in others. We developed a correlative approach to identify species’ response thresholds and locate ecological refuge areas associated with ...
Natalya M. Maitz   +5 more
wiley   +1 more source

高原环境对移居大鼠子代主要脏器指数及心脏形态学的影响

open access: yesZhongguo shiyan zhenduanxue, 2020
目的探讨移居高原大鼠子代在高原环境中主要脏器发育状况,观察移居高原大鼠子代心脏组织形态学改变。方法将24只(18只雌鼠,6只雄鼠)8周龄wistar大鼠平均分为高原组和平原组,每组12只(9只雌鼠,3只雄鼠)按3:1雌雄比例合笼受孕,所有孕鼠均自然分娩。比较高原组和平原组子代大鼠出生后的第1天、第30天、第60天心、肝、脾、肺、肾、脑的脏器指数,取心脏组织做HE染色检测病理学变化。结果高原组子代大鼠出生第1天体重低于平原组,分别为6.20±0.77g,6.60±0.90g ...
孙薇   +6 more
doaj  

胰岛素对缺氧大鼠认知损伤的保护作用研究

open access: yesZhongguo shiyan zhenduanxue, 2023
目的 探讨胰岛素对高原缺氧所致认知功能损伤的保护作用。方法 从低海拔空运20只大鼠至高原,随机分为4组,高原缺氧组(5只)、吸氧组(5只)、生理盐水组(5只)和胰岛素组(5只)。高原缺氧组大鼠在高原环境中正常饲养,吸氧组大鼠在到达高原后按2 L/h持续给氧3日,生理盐水组大鼠在达到高原后注射生理盐水3次/日,持续3日,胰岛素组大鼠在到达高原后给与胰岛素1.2 U/日,3次/日,持续给药3日。到达高原第4日,对4组大鼠进行Morris水迷宫测试,并观察大鼠大脑HE染色结果。结果 与吸氧组相比,高原缺氧组 ...
王飞   +5 more
doaj  

An Organo‐Pt(II) Photosensitizer With Robust Photo‐Assisted Antibacterial and Wound Recovery Performances in Diabetic Mice Wound Model

open access: yesRare Metals, Volume 45, Issue 7, July 2026.
ABSTRACT The pathogenesis of diabetic foot ulcers is complex, often involving polymicrobial infection and persistent inflammatory responses, which lead to delayed or nonhealing wounds, posing a formidable clinical challenge. Existing photodynamic therapy reagents and traditional treatments generally address only a single pathological aspect, and the ...
Yu Zhang   +16 more
wiley   +1 more source

卡格列净对肾病综合征的治疗作用及超声评价

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2023
目的探讨抗糖药物卡格列净(CGLZ)对阿霉素所致肾病综合征(NS)模型大鼠的治疗作用,以及超声造影(CEUS)联合彩色多普勒血流显像(CDFI)在治疗过程中的评价作用。方法56 只SD 雄性大鼠随机分为正常组(NG)、模型组(MG)、泼尼松(PAT)组(PG)、小剂量CGLZ 组(LSCG)、大剂量CGLZ 组(HSCG)、小剂量CGLZ + PAT 组(LUCG)和大剂量CGLZ +PAT 组(HUCG),每组8 只。采用阿霉素2 次尾静脉注射法诱导制备NS 大鼠模型,以常规PAT ...
洪文娟   +6 more
doaj  

An Ultrasound‐Triggered Antibacterial Hydrogel With Integrated Antioxidant and Angiogenic Functions for Infected Wound Care

open access: yesRare Metals, Volume 45, Issue 5, May 2026.
ABSTRACT Managing diabetic wounds requires simultaneously addressing their infectious, oxidative, and regenerative impairments. To address this, this study integrates a piezoelectric BiOCl@CuSe heterojunction (PFM‐verified) into an injectable F127/HA hydrogel, creating an ultrasound‐responsive smart dressing.
Jiayan Guo   +5 more
wiley   +1 more source

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