【目的】 研究妊娠期高血压疾病患者在孕16~20周外周血白细胞的基因表达谱,寻找妊娠期高血压疾病患者中孕早期外周血白细胞的差异表达基因,并选取异常脂代谢基因进行认证 【方法】 我院2008年8月至2008年12月间在我院产检且经B超确定孕期为16 ~ 20周的初产妇共800例,随访至妊娠结束,将最终发展为子痫前期的6例患者为研究组,40例正常妊娠妇女为对照组,应用人类全基因组cDNA单荧光芯片检测两组孕妇在妊娠16 ~ 20周时外周血白细胞差异基因表达谱;在差异表达基因中选取氧化修饰低密度脂蛋白 ...
doaj
患者,女,16岁,因"蛋白尿2年,血压升高半年"入院。既往患者2年前无诱因尿中泡沫增多,尿常规可见蛋白尿和血尿,考虑为"慢性肾炎",予中药治疗;半年前出现头晕,测血压220/110 nn Hg,予降压治疗,血压波动于140~220/80~100 nm Hg;2周前因头晕测血压220/140 mrn Hg;母亲妊娠时患妊高症,患者为34周早产儿,出生体质量2.0kg;无过敏史。入院查体身高145 cn,体质量36 kg,血压140/80 mmHg;甲状腺未及肿大,心肺查体未见异常 ...
李许民, 李月红, 杨冰, 左力
doaj
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